A5009335706- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Body Contouring and Surgery
- Minimally Invasive Surgical Techniques
- Obesity and Health Practices
- Diabetes Treatment and Management
- Abdominal Surgery and Complications
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Hernia repair and management
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Intestinal and Peritoneal Adhesions
- Regulation of Appetite and Obesity
- Esophageal Cancer Research and Treatment
- Cardiovascular Disease and Adiposity
- Intraperitoneal and Appendiceal Malignancies
- Cardiac Valve Diseases and Treatments
- Nutrition and Health in Aging
- Enhanced Recovery After Surgery
- Obesity, Physical Activity, Diet
- Aortic Disease and Treatment Approaches
- Eating Disorders and Behaviors
Columbia University
2010-2024
NewYork–Presbyterian Hospital
2003-2024
Columbia University Irving Medical Center
2009-2024
New York Proton Center
2009-2018
Presbyterian Hospital
1995-2011
New York Hospital Queens
2006-2011
Fox Chase Cancer Center
2010
City University of Seattle
2010
Columbia College
1997-2009
Royal College of Physicians
1997-2009
<h3>Importance</h3>Controlling glycemia, blood pressure, and cholesterol is important for patients with diabetes. How best to achieve this goal unknown.<h3>Objective</h3>To compare Roux-en-Y gastric bypass lifestyle intensive medical management control of comorbid risk factors.<h3>Design, Setting, Participants</h3>A 12-month, 2-group unblinded randomized trial at 4 teaching hospitals in the United States Taiwan involving 120 participants who had a hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>)...
To help understand the mechanisms by which weight loss is maintained after Roux-en-Y gastric bypass (RYGBP), we measured circulating concentrations of total and bioactive octanoylated ghrelin, peptide YY (PYY), glucose, insulin in fasted state response to a liquid test meal three groups adult women: lean (n = 8); weight-stable 35 ± 5 months RYGBP 12; mean body mass index, 33 kg/m2); matched surgical group for index age 12). Fasting plasma ghrelin levels were nearly identical between (425 54...
Context: Bariatric surgery is common and may be associated with deleterious effects on the skeleton. Objective: Our objective was to assess bone metabolism mineral density (BMD) after Roux-en-Y gastric bypass. Design Setting: We conducted a 1-yr prospective longitudinal study at university hospital bariatric practice metabolic disease unit. Participants: Participants included 23 obese (mean body mass index 47 kg/m2) men women, aged 20–64 yr. Main Outcome Measures: Serum PTH,...
Marked improvement in glycemic control occurs patients with type 2 diabetes mellitus shortly after Roux-en-Y gastric bypass surgery (RYGB) and before there is major weight loss. The objective of this study was to determine whether the magnitude change primarily due caloric restriction or unique surgical procedure. We studied eleven subjects who underwent RYGB fourteen mean-matched for BMI, HbA1c, duration were admitted our inpatient research unit given a very low–calorie diet (VLCD) 500...
Abstract Objective: To quantify plasma concentrations of hormones that regulate energy homeostasis in order to establish possible mechanisms for greater weight loss after Roux‐en‐Y gastric bypass (RYGBP) compared with banding (BND). Research Methods and Procedures: Four groups women were studied: lean ( n = 8; mean BMI, 21.6 kg/m 2 ); BND 9; 35.8; 25% loss), RYGBP 34.2; 36% controls matched BMI the surgical 11; 34.4). Results: Fasting total peptide YY (PYY) PYY (3–36) immunoreactivity...
ABSTRACT Although vitamin D deficiency is prevalent among obese individuals, its cause poorly understood. Few studies have measured concentrations in adipose of (OB) subjects, and none included normal weight controls (C). The goal this study was to investigate whether the relationship between body composition, serum 25-hydroxyvitamin (25OHD), subcutaneous (SQ) omental (OM) adipose, total stores differ OB C. Obese women undergoing bariatric surgery normal-weight abdominal for benign...
Bariatric surgery results in bone loss at weight-bearing sites, the mechanism of which is unknown.Twenty-two women (mean body mass index 44 kg/m(2); aged 45 years) who underwent Roux-en-Y gastric bypass (n = 14) and restrictive procedures 8) had measurements areal mineral density by dual-energy x-ray absorptiometry lumbar spine, total hip (TH), femoral neck (FN), one third radius trabecular cortical volumetric microstructure distal tibia high-resolution peripheral quantitative computed...
This study was undertaken to investigate the ability of a high-pressure CO2 environment aerosolize tumor cells in both vitro and vivo models. (An aerosol is defined as stable gaseous suspension insoluble particles). Also, this designed determine if rapid desufflation capable transporting fluid laden with cells.The four experiments were performed an 18.9-1 plastic vessel fitted two 7-mm ports compliant latex balloon affixed top. After insufflation, desufflated through sterile soluset...
PURPOSE: We evaluated cell-mediated immune function after laparoscopic-assisted and open bowel resection in rats by measuring delayed-type hypersensitivity responses to keyhole limpet hemocyanin (KLH) phytohemagglutinin (PHA). METHODS: Male Sprague-Dawley (n=120) were sensitized 1 mg of KLH ten days before investigations. Rats challenged preoperatively, immediately postoperatively, on postoperative day (POD) 2 with an intradermal injection 0.3 0.2 PHA (at different sites). Averages two...
In Brief Introduction: Initial excitement for Natural Orifice Transluminal Endoscopic Surgery (NOTES) has been partly tempered by the reality that a NOTES procedure without laparoscopic or needleoscopic-assistance not performed most groups. After safely performing laparoscopically-assisted transvaginal cholecystectomy in an IACUC-approved porcine model, we embarked on IRB-approved protocol to ultimately perform pure cholecystectomy. Materials and Methods: We describe our experience with true...
Vascular endothelial growth factor (VEGF) is a potent inducer of angiogenesis that necessary for wound healing and also promotes tumor growth. It anticipated plasma levels would increase after major surgery such elevations may facilitate This study's purpose was to determine VEGF before early open minimally invasive abdominal surgery.Colorectal resection cancer (n = 139) or benign pathology 48) gastric bypass morbid obesity 40) were assessed. Similar numbers laparoscopic patients studied...
<b>Background and study aims</b> Staple-line leaks occur in 1 % – 7 of patients who undergo sleeve gastrectomy, can be challenging to treat. The success endoscopic approaches decreases as develop into chronic sinus tracts. Endoscopic septotomy has been used facilitate healing refractory by incision enlargement the tract allow direct communication with gastric lumen internal drainage. <b>Patients methods</b> We reviewed technique outcomes among underwent at two centers for management...
Background Laparoscopic sleeve gastrectomy (SG) has surpassed Roux-en-Y gastric bypass (RYGB) as the most prevalent bariatric procedure worldwide. While RYGB and SG demonstrate equivalent short-term weight loss, long-term loss tends to be greater after RYGB. Differences in effect of these procedures on gastrointestinal hormones that regulate energy homeostasis are felt partially underlie differences outcomes. The objective this study was prospectively quantify blood levels gut glucose at one...