A5102387913- Immune cells in cancer
- Glycosylation and Glycoproteins Research
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
- Adenosine and Purinergic Signaling
- Histone Deacetylase Inhibitors Research
- Diabetes and associated disorders
- Cytokine Signaling Pathways and Interactions
- Inflammatory mediators and NSAID effects
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Peptidase Inhibition and Analysis
- Protein Tyrosine Phosphatases
- Galectins and Cancer Biology
- Rheumatoid Arthritis Research and Therapies
- Ocular Diseases and Behçet’s Syndrome
West China Hospital of Sichuan University
2024-2025
Sichuan University
2024-2025
Changzhou No.2 People's Hospital
2012-2021
Nanjing Medical University
2012-2021
ABSTRACT Aging is an inevitable biological process, driven in part by increased oxidative stress, which accelerates cellular damage and contributes to immune system dysfunction. Therefore, targeting stress has emerged as a potential strategy. Pyrroloquinoline quinone (PQQ), potent antioxidant, demonstrated significant efficacy reducing modulating responses, making it promising therapeutic candidate. In this study, we investigated the effects of aging on hematopoietic (HIS) through...
Autoimmune uveitis (AU) is a prevalent ocular autoimmune disease leading to significant visual impairment. However, underlying pathogenesis of AU required develop more efficient therapy remain unclear.
T-cell immunoglobulin and mucin domain-4 (TIMD-4) are likely to impact autoimmune diseases (e.g., rheumatoid arthritis (RA)). It is hypothesized here that TIMD-4 gene polymorphism display a correlation with the RA risk.For examining effect exerted by genetic variant in risk, case-control study containing 379 cases 432 healthy control groups Chinese population was performed. This conducted genotyping use of custom-by-design 48-Plex single nucleotide (SNP) Scan™ Kit. Blood serum conditions...