Angiogenesis is one of the important factors related to tumorigenesis, invasion, and metastasis. Cancer-secreted exosomes are essential mediators intercellular cross-talk participate in angiogenesis Unveiling mechanism an way develop anti-angiogenesis therapeutic strategies against cancer progression. miR-1825 expression relationship with microvascular density were validated colorectal (CRC) by situ hybridization (ISH) staining immunohistochemistry (IHC). Sequential differential...

Improving the quality of built environment to enhance people’s mental health is gaining traction across various fields, precipitating valuable actions on wave “Healthy China 2030” initiative. While ample studies have confirmed benefits interaction with natural or green spaces, investigation into restorative potential in urban settings remains notably underexplored. In this study, we focused historical districts, conducting a questionnaire survey evaluate experiences individuals visiting...

As quantum programming evolves, more and languages are being developed. a result, debugging testing programs have become increasingly important. While bug fixing in classical has come long way, there is lack of research programs. To this end, paper presents comprehensive study on We collect investigate 96 real-world bugs their fixes from four popular (Qiskit, Cirq, Q#, ProjectQ). Our shows that high proportion quantum-specific (over 80%), which requires further the domain. also summarize...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with a poor prognosis. Type X collagen α 1 chain (COL10A1), member family, gene associated progression variety human tumors, but specific function and molecular mechanism COL10A1 in pancreatic cancer remain unclear. Our study found that highly expressed cells tissues, its high expression related to prognosis some clinicopathological features, such as tumor size differentiation. Biological functional...

Highlights•miR-1825 is upregulated in CRC and associated with progression•circTBC1D22A functions as an efficient miR-1825 sponge cells•ATG14 functional target of cells•circTBC1D22A regulates autophagy via miR-1825/ATG14 axisSummaryDistant metastasis the main cause death patients colorectal cancer (CRC). A better understanding mechanisms can greatly improve outcome CRC. Accumulating evidence suggests that circRNA plays pivotal roles progression metastasis, especially acting a miRNA to...

Purpose This paper aims to study the influence of microparticles on surface cavitation behavior 2Cr3WMoV steel; microparticle suspensions different concentration, particle size, material and shape were prepared based ultrasonic vibration experimental device. Design/methodology/approach steel was taken as research object for experiment. The morphology, quantity distribution pits observed analyzed by metallographic microscope scanning electron microscope. Findings findings showed that process...

Summary Rice glutelin is poorly soluble which restricts its potential food application. Succinylation a chemical modification that improves the solubility of proteins by derivatising ɛ‐amino group lysine residues. In this study, rice was modified succinic anhydride at different concentrations (10%, 20%, 30%, 40%, and 50%). The succinylated samples showed enhanced solubility, reduced particle size, increased absolute zeta values. emulsifying foaming properties were also significantly...

Envy-freeness is one of the most prominent fairness concepts in allocation indivisible goods. Even though trivial envy-free allocations always exist, rich literature shows this not true when additionally requires some efficiency concept (e.g., completeness, Pareto-efficiency, or social welfare maximization). In fact, such case even deciding existence an efficient notoriously computationally hard. paper, we explore limits computability by relaxing standard and analyzing how impacts...

Quantum computing has emerged as a promising domain for the machine learning (ML) area, offering significant computational advantages over classical counterparts. With growing interest in quantum (QML), ensuring correctness and robustness of software platforms to develop such QML programs is critical. A necessary step reliability understand bugs they typically suffer from. To address this need, paper presents first comprehensive study frameworks. We inspect 391 real-world collected from 22...

The pigmentation of various components leads to different colors roses. However, the intricate molecular machinery and metabolic pathways underlying rose remain largely unexplored. In this study, we determined that pink black-red petals contain abundant anthocyanins, reaching concentrations 800 μg/g 1400 μg/g, respectively, significantly surpassing those in white yellow petals. We identified 22 key anthocyanin components, predominantly cyanidin, pelargonidin, delphinidin, peonidin,...

Crop classification using polarimetric SAR data is one of the most important applications in Polarimetric Synthetic Aperture Radar (PolSAR) imagery. Obviously, for crop classification, multi-temporal PolSAR can provide more information than single-temporal data, but processing method matching image relatively backward. Aiming at high-dimensional composed PolSAR, this paper proposes a to integrate stacked auto-encoder network and convolutional neural network, making full use dimension...

Liquid-liquid phase separation (LLPS) impact immune signaling in cancer and related genes have shown prognostic value breast (BRCA). However, the crosstalk between LLPS infiltration BRCA remain unclear. Therefore, we aimed to develop a novel model of infiltration. BRCA-related, liquid-liquid (LLPS)-related genes, differentially expressed (DEGs) were identified using public databases. Mutation drug sensitivity analyses performed Gene Set Cancer Analysis database. Univariate cox regression...

Based on field observations and examinations of herbarium specimens (including type material), consulting the original literature molecular phylogenetic analysis rbcL trnL-F sequences, it is concluded that Hypolepis robusta conspecific with alpina here formally treated as a synonym it. Additionally H. reported new distribution records in Guangdong, Guangxi Hainan Island China, respectively.

With the development of open science and technological innovation, using sharing data molecular biology techniques in study taxonomy systematics have become a crucial component plants, which undoubtedly helps us discover more hidden outliers or deal with difficult taxa. In this paper, we take Dennstaedtia smithii as an example, based on database, virtual herbarium plant photo bank, to clarify that been find key morphological traits consistent systematics. phylogenetic analyses, used rbcL,...

Smart home provides people with a more convenient and intelligent way of living it is one the most widely used application Internet Things (IoT). However, building smart laboratory for students to visit learn labor intensive time consuming. In order meet demand experimental teaching in higher education, this paper designed developed Virtual Simulation Experimental Platform (VSEP) home. Firstly, we introduced goals, platform architecture functional modules system. Then, development process...