A5037945794- Childhood Cancer Survivors' Quality of Life
- Clinical Nutrition and Gastroenterology
- Acute Lymphoblastic Leukemia research
- Child Nutrition and Water Access
- Nutrition and Health in Aging
- Child Nutrition and Feeding Issues
- Diet and metabolism studies
- Lipoproteins and Cardiovascular Health
- CAR-T cell therapy research
- Regulation of Appetite and Obesity
- Immune Cell Function and Interaction
- Complementary and Alternative Medicine Studies
- Health Promotion and Cardiovascular Prevention
- Neonatal Health and Biochemistry
- Phytochemistry Medicinal Plant Applications
- Obesity, Physical Activity, Diet
- Biochemical Analysis and Sensing Techniques
- Clinical practice guidelines implementation
- Vitamin C and Antioxidants Research
- Global Cancer Incidence and Screening
- Sports Performance and Training
- Muscle metabolism and nutrition
- Colorectal Cancer Screening and Detection
- Pharmaceutical Economics and Policy
- Head and Neck Cancer Studies
Universidad de Guadalajara
2006-2025
MaineHealth
2025
Hospital Civil de Guadalajara
2006-2024
Goethe University Frankfurt
2018-2022
Frankfurt Cancer Institute
2022
Novartis (Germany)
2021
Centro de Epilepsia y Neurocirugía Funcional
2007-2008
Friedrich Schiller University Jena
2006
Abstract Acute myeloid leukemia (AML) is a malignant disorder derived from neoplastic progenitor cells characterized by abnormal proliferation and differentiation. Although novel therapeutics have recently been introduced, AML remains therapeutic challenge with insufficient cure rates. In the last years, immune-directed therapies such as chimeric antigen receptor (CAR)-T were which showed outstanding clinical activity against B-cell malignancies including acute lymphoblastic (ALL). However,...
Childhood acute lymphoblastic leukemia (ALL) is a malignancy with varying survival rates across countries low, middle, and high income. The assessment of nutritional status (NS) using anthropometric indicators has been explored for its potential relationship on treatment outcomes. This study analyzed 3-year retrospective cohort Mexican pediatric patients ALL, exploring the association between NS at diagnosis relapse/mortality. Retrospective observational study. Medical records from 252 ALL...
Abstract Poor access to care among rural and vulnerable populations may result in later stage cancer diagnoses. Using Maine Cancer Registry data (2017-2021) we examined relationships between rurality, insurance, area deprivation index (ADI), for breast, colorectal, lung/bronchus, prostate cancers. Among 21,208 cancers, regional/distant spread at diagnosis was present 24% of 60% 69% 25% prostate. In multivariable model modeled odds being diagnosed with (vs situ/local spread) according ADI....
Context: Leptin might be more important as a starvation hormone than satiety signal. The role of the soluble leptin receptor (sOB-R) and its regulation in children with protein energy malnutrition (PEM) is poorly understood. Design: We elucidated effect intensive nutritional support on axis 26 severely malnourished toddlers who received infant milk-based formula for 2 wk via continuous enteral tube feeding followed by ad libitum feeding. Serum levels leptin, sOB-R, IGF-I, IGF-binding...
BACKGROUND Children with cancer in high‐income and low‐income countries often use traditional complementary/alternative medicine (TCAM). With efforts by the World Health Organization international twinning programs improving access to conventional care for patients childhood cancer, understanding global of TCAM is important because reliance on may affect time presentation, adherence, abandonment care. In current study, authors describe process validation an survey documenting among children...
The subjective global assessment (SGA) is a simple, sensitive tool used to identify nutritional risk. It widely in the adult population, but there little evidence on its effectiveness children with cancer.This cross-sectional study was undertaken demonstrate significant correlation between simplified version of Patient-Generated SGA (PG-SGA) and anthropometric status recently diagnosed cancer.The 70 pediatric cancer patients assessed PG-SGA measurements. relation assessments tested ANOVA,...
Objective. To evaluate the association of waist‐height index (WHI) and body adiposity (BAI) with cardiovascular risk factors (CVRF) in children adolescents obesity. Methods. Cross‐sectional study 40 subjects obesity (BMI 蠅 2.0 SD). Body weight, height, waist (WC) hip circumference (HC), blood pressure, serum glucose insulin (HOMA), total cholesterol, LDL, HDL triglycerideswere measured. WHI (WC/ height) BAI (HC/height 1.5 ‐18) were calculated. composition was assessed by DEXA. Simple...
Abstract Background Lowering low-density lipoprotein cholesterol (LDL-C) in hypercholesterolemia patients at very high cardiovascular (CV) risk is essential preventing future CV events. However, LDL-C targets often remain unattained. Purpose The purpose of the present survey was to identify possible reasons for insufficient target achievement despite availability efficacious lipid lowering drugs clinical setting management secondary prevention Germany. Methods PROCYON an online with over...
Objective. The purpose is to show lipid peroxide’s serum concentration trend during a four-week nutritional recovery period in children with primary and severe protein energy malnutrition (PEM). Methods. In clinical intervention 12 primarily severely malnourished children (three 48 months of age) were included. Dependent variable: Serum peroxide (LPO) (nmol/mL). Independent variables: non lactose starting infant formula (200 kcal/kg/d proteins 4 g/kg/d). Age, sex, recovery, weight/age,...
Background: Oral mucositis (OM) is a common side effect of antineoplastic-drug administration. It frequently related to risk infection and poor intake foods fluids. This might adversely affect the patients’ nutritional status, cause dose reductions, prolong treatment time length hospital stay, increases costs treatment. Aim: To investigate if use glutamine (Gln) administered by mouthwash during methotrexate(MTX)-chemotherapy in consolidation-phase reduces oral children with acute...
Little is known how hormones and immune response indicators correlate in malnourished children during nutritional recovery. We undertook a clinical assay on 22 severely < 48 months of age who received formula without lactose via enteral feeding for two weeks ad libitum more. Concentration IGF-I, IGFBP-3, leptin, sOB-R; and, cellular serum concentration IL-2 CD4+and CD8+T cells were obtained. A multiple Spearman correlation among variables was used. At start positive correlations between...
With the purpose to demonstrate effect of intensive nutritional support on cellular and serum concentration IL‐2 in children with severe protein energy malnutrition a clinical assay was carried out tertiary care hospital 10 severely malnourished < 48 months age who received formula without lactose via enteral feeding for two weeks ad libitum an additional were included. Cellular concentrations subpopulation CD4+ CD8+ obtained. A control group (n = 13) paired student t test initial‐final...
Abstract Background In Germany, cardiovascular (CV) disease was the leading cause of mortality (39% all deaths), responsible for 340,000 deaths in 2014 (1). Considering its role as a major risk factor CV disease, awareness hypercholesterolemia clinical practice seems insufficient. Purpose The purpose present survey to identify patients' journey differences between primary and secondary prevention patients with hypercholesterolemia. Methods PROCYON two-part online on perception, awareness,...