- Marine Ecology and Invasive Species
- Plant and Biological Electrophysiology Studies
- Planarian Biology and Electrostimulation
- Photoreceptor and optogenetics research
- Advanced Fluorescence Microscopy Techniques
- Nanoplatforms for cancer theranostics
Westlake University
2020-2024
Hangzhou Academy of Agricultural Sciences
2020
Cyclooctatetraene-conjugated cyanine dyes represent an effective strategy to improve biocompatibility under light in live-cell fluorescence imaging and analysis of mitochondria.
Tissue regeneration is a complex process involving large changes in cell proliferation, fate determination, and differentiation. Mitochondrial dynamics metabolism play crucial role development wound repair, but their function large-scale remains poorly understood. Planarians offer an excellent model to investigate this due remarkable regenerative abilities. In study, we examine mitochondrial during planarian regeneration. We find that knockdown of the fusion gene, opa1, impairs both tissue...
Abstract Background The pluripotent stem cells in planarians, a model for tissue and cellular regeneration, remain further identification. We recently developed method to enrich piwi-1 + Schmidtea mediterranea , by staining with SiR-DNA Cell Tracker Green, named SirNeoblasts that permits their propagation subsequent functional study vivo. Since traditional enrichment planarian neoblasts Hoechst 33342 generates X1 cells, blocking the cell cycle inducing cytotoxicity, this Green represents...