Christopher Doughty

ORCID: 0009-0002-0882-8366
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About
Contact & Profiles
Research Areas
  • Innovations in Medical Education
  • Peripheral Neuropathies and Disorders
  • Clinical Reasoning and Diagnostic Skills
  • Chronic Lymphocytic Leukemia Research
  • Botulinum Toxin and Related Neurological Disorders
  • Inflammatory Myopathies and Dermatomyositis
  • Peripheral Nerve Disorders
  • Pain Mechanisms and Treatments
  • Stroke Rehabilitation and Recovery
  • Acute Ischemic Stroke Management
  • Advanced Neuroimaging Techniques and Applications
  • Myasthenia Gravis and Thymoma
  • Healthcare Systems and Technology
  • Immunodeficiency and Autoimmune Disorders
  • Myofascial pain diagnosis and treatment
  • Dysphagia Assessment and Management
  • Monoclonal and Polyclonal Antibodies Research
  • Nursing Roles and Practices
  • Nerve Injury and Rehabilitation
  • Empathy and Medical Education
  • Clinical practice guidelines implementation
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Multiple Myeloma Research and Treatments
  • Orthopedic Surgery and Rehabilitation
  • Biomedical and Engineering Education

Brigham and Women's Hospital
2016-2025

Harvard University
2015-2025

Massachusetts General Hospital
2017-2024

University of Iowa
2023

Westchester Medical Center
2023

New York Medical College
2023

University of California San Francisco Medical Center
2022

Dominican University of California
2022

Brigham and Women's Faulkner Hospital
2021

Fenway Health
2020

Objective The aim of this work was to investigate whether an imaging measure corticospinal tract (CST) injury in the acute phase can predict motor outcome at 3 months comparison clinical assessment initial impairment. Methods A two‐site prospective cohort study followed up a group first‐ever ischemic stroke patients using Upper‐Extremity Fugl‐Meyer (UE‐FM) Scale impairment and months. weighted CST lesion load (wCST‐LL) calculated by overlaying patient's map on magnetic resonance with...

10.1002/ana.24510 article EN Annals of Neurology 2015-08-20

Expanding the US Food and Drug Administration-approved indications for immune checkpoint inhibitors in patients with cancer has resulted therapeutic success immune-related adverse events (irAEs). Neurologic irAEs (irAE-Ns) have an incidence of 1%-12% a high fatality rate relative to other irAEs. Lack standardized disease definitions accurate phenotyping leads syndrome misclassification impedes development evidence-based treatments translational research. The objective this study was develop...

10.1136/jitc-2021-002890 article EN cc-by-nc Journal for ImmunoTherapy of Cancer 2021-07-01

Background and Purpose— A decrease in fractional anisotropy (FA) of the ipsilesional corticospinal tract (CST) distal to stroke lesions subacute (eg, 30 days) chronic phase has been correlated with poor motor outcomes, but it is unclear whether FA values obtained within acute (here defined as 80 hours after onset) can predict later outcome. Methods— Fifty-eight patients underwent an assessment impairment at 3 months using upper extremity Fugl-Meyer assessment. values, onset, were determined...

10.1161/strokeaha.115.012088 article EN Stroke 2016-05-06

Inclusion body myositis is the most common progressive muscle wasting disease in people older than 50 years, with no effective drug treatment. Arimoclomol an oral co-inducer of cellular heat shock response that was safe and well-tolerated a pilot study inclusion myositis, reduced key pathological markers two in-vitro models representing degenerative inflammatory components this disease, improved pathology function mutant valosin-containing protein mice. In current study, we aimed to assess...

10.1016/s1474-4422(23)00275-2 article EN cc-by The Lancet Neurology 2023-09-20

A growing number of nurse practitioners (NPs) are entering neurologic practice. Postgraduate educational needs NPs partly dictated by previous experience, which is not well defined. We aim to describe education in NP programs better inform efforts develop tailored initiatives. website review was performed identify accredited and program leaders. previously developed survey designed facilitate a description physician assistant (PA) adapted for leaders an iterative approach. The distributed...

10.1212/ne9.0000000000200190 article EN Neurology Education 2025-02-05

Objective Pneumonia is a morbid complication of stroke, but evidence‐based strategies for its prevention are lacking. Acid‐suppressive medications have been associated with increased risk nosocomial pneumonia in hospitalized patients. It unclear whether these results can be extrapolated to stroke patients, where other factors strongly modulate risk. We investigated the association between acid‐suppressive medication and hospital‐acquired patients acute stroke. Methods All ischemic or...

10.1002/ana.24262 article EN Annals of Neurology 2014-08-28

To assess the operating characteristics of Beck-Depression Inventory-II (BDI-II) and BDI-II cognitive subscale (BDI-II-cog) in screening for major depression (MDD) post-myocardial infarction (MI) patients.Between October 2003 July 2005, 131 post-MI patients admitted to an urban academic medical center completed a semi-structured interview within 72 hours symptom onset. Sensitivity, specificity, positive negative predictive values, overall correct classification, likelihood ratios various...

10.2190/pm.40.2.e article EN The International Journal of Psychiatry in Medicine 2010-06-01

Neurology residency training is inpatient focused, underemphasizing outpatient disorders. We implemented a novel didactic series of facilitated discussions between patient and their neurologist to expose residents topics management skills.

10.1212/ne9.0000000000200043 article EN cc-by Neurology Education 2023-02-01

Optimal management of myasthenia gravis (MG) in individuals ≥65 y old is unknown and patient factors may limit therapeutic choices. Safety efficacy rituximab older patients with MG has not been well-studied.This retrospective study examined 40 (14 old) treated for MG. The primary outcome was the proportion reaching "Improved" or better on Myasthenia Gravis Foundation America (MGFA) Post-Intervention Status (PIS) at 12 mo, compared between younger patients.Ninety-two percent achieved MGFA PIS...

10.1002/mus.27393 article EN Muscle & Nerve 2021-08-11

Abstract: The COVID-19 pandemic has led to a sudden shift toward virtual learning in neurology education, which presents challenges for educators. However, is here stay three key reasons: demand among students, ease of dissemination, and potential improve educational quality. Despite challenges, educators can teach effectively using appropriate tools methods, with innovative approaches that will ultimately lead sustained improvements education. Here, we aim help incorporate instruction into...

10.2147/amep.s413816 article EN cc-by-nc Advances in Medical Education and Practice 2023-10-01

A growing number of advanced practice providers (APPs) are entering neurologic practice, and educational initiatives focused on postgraduate training in neurology for these turn. Neurologic education APP degree programs is not well defined, which limits the ability to tailor specific needs APPs. We aim describe physician assistant (PA) better inform efforts.

10.1212/ne9.0000000000200029 article EN cc-by Neurology Education 2022-12-02
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