A5113966860- Gestational Trophoblastic Disease Studies
- Prenatal Screening and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Maternal and fetal healthcare
- Antenna Design and Analysis
The Netherlands Cancer Institute
2021-2025
To provide evidence for a reduced surveillance protocol to detect gestational trophoblastic neoplasia after normalisation of human chorionic gonadotrophin (hCG) levels following uterine evacuation complete hydatidiform mole. National retrospective population study. Two UK Trophoblastic Disease Treatment Centres (Sheffield and London), 1 January 1980 30 November 2020. 17 424 patients with hCG their mole were included. Complete moles verified by centralised pathological review. Patients...
<h3>Introduction/Background</h3> Low-risk gestational trophoblastic neoplasia (GTN) is treated with single-agent chemotherapy. In Europe, methotrexate folinic acid rescue (MTX/FA) the usual first-line therapy, and in event of resistance, a switch made to dactinomycin (ACT-D). There are two regimens ACT-D, 5-day regimen biweekly pulsed regimen. no large cohort studies investigate differences efficacy or chemotoxicity between support choice treatment. The aim this study was assess primary...
<h3>Introduction/Background*</h3> Partial molar pregnancy with a coexisting fetus (PHMCF) is very rare entity leading to limited understanding of its natural course and optimal diagnostics treatment. The aim this study was describe case series patients PHMCF review the current available literature. <h3>Methodology</h3> We searched databases Charing Cross Trophoblastic Disease Center Dutch Working Party on Tumors. Secondly, we performed systematic literature evaluate incidence PHMCF, clinical...
<h3>Introduction/Background</h3> In every woman with a hydatidiform mole pregnancy hCG-levels will be monitored after evacuation. If persist or relapse normalization gestational trophoblastic neoplasia (GTN) is diagnosed and chemotherapeutic treatment required. <h3>Purpose</h3> Following evacuation of complete (CHM), the relative risk malignant change hCG uncertain. Here we examine this question in large national data-set. <h3>Methodology</h3> All registered cases CHM Charing Cross Hospital...