Kaiyu Sun

ORCID: 0009-0002-3214-0131
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Immune cells in cancer
  • Ferroptosis and cancer prognosis
  • Cancer Immunotherapy and Biomarkers
  • Diabetes and associated disorders
  • Cytokine Signaling Pathways and Interactions
  • Gastric Cancer Management and Outcomes
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Radiomics and Machine Learning in Medical Imaging
  • interferon and immune responses
  • Phagocytosis and Immune Regulation
  • Immune Cell Function and Interaction
  • Esophageal and GI Pathology
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Intestinal Malrotation and Obstruction Disorders
  • RNA Research and Splicing
  • Chemokine receptors and signaling
  • Cancer, Lipids, and Metabolism

The First Affiliated Hospital, Sun Yat-sen University
2020-2023

Sun Yat-sen University
2020-2023

Air Force Medical University
2020

The tumor microenvironment is distinctive in primary and secondary liver cancer. B cells represent an important component of immune infiltrates. Here, we demonstrated that are regulator hepatocellular carcinoma (HCC) colorectal cancer metastasis (CRLM) microenvironments. displayed distinct developmental trajectories HCC CRLM. Single-cell analysis revealed IgG+ plasma preferentially accumulated HCC, whereas IgA+ were enriched Mechanistically, recruited by tumor-associated macrophages via the...

10.1158/0008-5472.can-23-0193 article EN Cancer Research 2023-06-23

Abstract Background: Neoadjuvant chemotherapy is a promising treatment option for potential resectable gastric cancer, but patients’ responses vary. We aimed to develop and validate radiomics score (rad_score) predict response neoadjuvant investigate its efficacy in survival stratification. Methods: A total of 106 patients with before gastrectomy were included (training cohort: n =74; validation =32). Radiomics features extracted from the pre-treatment portal venous-phase CT. After feature...

10.21203/rs.2.17517/v2 preprint EN cc-by Research Square (Research Square) 2020-05-01

<div>Abstract<p>The tumor microenvironment is distinctive in primary and secondary liver cancer. B cells represent an important component of immune infiltrates. Here, we demonstrated that are regulator hepatocellular carcinoma (HCC) colorectal cancer metastasis (CRLM) microenvironments. displayed distinct developmental trajectories HCC CRLM. Single-cell analysis revealed IgG<sup>+</sup> plasma preferentially accumulated HCC, whereas IgA<sup>+</sup> were...

10.1158/0008-5472.c.6908384.v1 preprint EN 2023-11-01

<div>Abstract<p>The tumor microenvironment is distinctive in primary and secondary liver cancer. B cells represent an important component of immune infiltrates. Here, we demonstrated that are regulator hepatocellular carcinoma (HCC) colorectal cancer metastasis (CRLM) microenvironments. displayed distinct developmental trajectories HCC CRLM. Single-cell analysis revealed IgG+ plasma preferentially accumulated while IgA+ were enriched Mechanistically, recruited by tumor-associated...

10.1158/0008-5472.c.6908384.v2 preprint EN 2024-09-16
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