Umberto Attanasio

ORCID: 0009-0002-3438-1537
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About
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Research Areas
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Pulmonary Hypertension Research and Treatments
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Chemotherapy-induced organ toxicity mitigation
  • Cancer Treatment and Pharmacology
  • Cardiac Arrhythmias and Treatments
  • Vascular Anomalies and Treatments
  • Hemoglobin structure and function
  • Lung Cancer Research Studies
  • Congenital Heart Disease Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiovascular Issues in Pregnancy
  • Systemic Sclerosis and Related Diseases
  • Coronary Artery Anomalies
  • Health Systems, Economic Evaluations, Quality of Life
  • Mitochondrial Function and Pathology
  • Cardiac tumors and thrombi
  • Heme Oxygenase-1 and Carbon Monoxide
  • Bioinformatics and Genomic Networks
  • Diabetes Treatment and Management
  • Rheumatoid Arthritis Research and Therapies
  • Electron Spin Resonance Studies
  • Cardiovascular and exercise physiology
  • Cardiac Imaging and Diagnostics

Federico II University Hospital
2019-2025

Serum biomarkers represent a reproducible, sensitive, minimally invasive and inexpensive method to explore possible adverse cardiovascular effects of antineoplastic treatments. They are useful tools in risk stratification, the early detection cardiotoxicity follow-up prognostic assessment cancer patients. In this literature review, we aim at describing current state knowledge on meaning usefulness patients with cancer; analyzing intricate relationship between disease (especially HF) how...

10.3390/biom14020199 article EN cc-by Biomolecules 2024-02-07

Background and Objectives: Along with the ageing of population, cancer cardiovascular (CV) diseases more frequently coexist, complicating patients’ management. Here, we focus on elderly oncologic patients, describing clinical features comorbidities, discussing therapeutic management CV risk factors complications risen during our follow-up, exploring different items comprehensive geriatric assessment (CGA) correlation between cardiac function by means standard 2D echocardiography each CGA...

10.3390/jcm14093257 article EN Journal of Clinical Medicine 2025-05-07

Rationale Pulmonary arterial hypertension (PAH) is a rare disease characterised by limited survival despite remarkable improvements in therapy. The causes, clinical burden and outcomes of patients admitted to the intensive care unit (ICU) remain poorly characterised. aim this study was describe patient characteristics, causes ICU hospitalisation, risk factors for 1-year mortality. Methods Data from enrolled Johns Hopkins Hypertension Registry were analysed period between January 2010...

10.1183/23120541.00002-2022 article EN cc-by-nc ERJ Open Research 2022-04-01

Abstract Aims Individual prognostic assessment and disease evolution pathways are undefined in chronic heart failure (HF). The application of unsupervised learning methodologies could help to identify patient phenotypes the progression each phenotype as well assess adverse event risk. Methods results From a bulk 7948 HF patients included MECKI registry, we selected with minimum 2‐year follow‐up. We implemented topological data analysis (TDA), based on 43 variables derived from clinical,...

10.1002/ehf2.14966 article EN cc-by-nc ESC Heart Failure 2024-09-24

Many variables obtained during cardiopulmonary exercise test (CPET), including O2 uptake (VO2) versus heart rate (HR, O2-pulse) and work (VO2/Watt), provide quantitative patterns of responses to when left ventricular dysfunction is an effect myocardial ischemia (MI). Therefore, CPET offers a unique approach evaluate exercise-induced MI in the presence fixed or dynamic coronary arteries stenosis. In this paper, we examined case 74-year-old patient presenting with ischemic normal stress...

10.3390/jcm12175764 article EN Journal of Clinical Medicine 2023-09-04

Background and aims. Functional capacity measured with cardiopulmonary exercise testing (CPET) is extensively studied in patients cardiovascular diseases. In the current prospective study, we aim at exploring role of CPET oncologic evaluating its variation administration treatments. Material methods. We analyzed 77 maximal CPETs from older adult cancer assessed capacity. were performed before starting (t0), during (t1) end (t2) The main outcome was death for all causes. Results. t0 t1 showed...

10.36150/2499-6564-n638 article EN cc-by-nc-nd Journal of Gerontology and Geriatrics 2023-09-01
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