A5044401066- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Treatments and Mutations
- Cancer Treatment and Pharmacology
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Liver Disease and Transplantation
- Lung Cancer Research Studies
- Renal cell carcinoma treatment
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Sarcoma Diagnosis and Treatment
- Esophageal and GI Pathology
- Urological Disorders and Treatments
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- COVID-19 and healthcare impacts
- Dysphagia Assessment and Management
- Colorectal and Anal Carcinomas
- Oral and Maxillofacial Pathology
- Chemotherapy-induced cardiotoxicity and mitigation
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2015-2025
Ospedale Generale Regionale Francesco Miulli
2025
Polytechnic University of Turin
2023-2024
Federico II University Hospital
2021-2024
Ospedale Monaldi
2001-2022
Université de Rouen Normandie
2003-2019
Centre Hospitalier Universitaire de Rouen
2014
Laboratoire National Henri Becquerel
2014
Churchill Hospital
2008-2009
Istituti di Ricovero e Cura a Carattere Scientifico
2008-2009
Objective To describe the safety and efficacy of radiofrequency ablation (RFA) to treat unresectable malignant hepatic tumors in 123 patients. Background The majority patients with primary or metastatic malignancies confined liver are not candidates for resection because tumor size, location, multifocality inadequate functional reserve. Local application heat is tumoricidal; therefore, authors investigated a novel RFA system cancer. Patients Methods were entered into prospective,...
A multicenter analysis was conducted to evaluate the main prognostic factors driving survival after radioembolization using yttrium-90-labeled resin microspheres in patients with hepatocellular carcinoma at eight European centers. In total, 325 received a median activity of 1.6 GBq between September 2003 and December 2009, predominantly as whole-liver (45.2%) or right-lobe (38.5%) infusions. Typically, were Child-Pugh class (82.5%), had underlying cirrhosis (78.5%), good Eastern Cooperative...
In Brief Background: Radiofrequency ablation (RFA) has become a common treatment of patients with unresectable primary and secondary hepatic malignancies. We performed this prospective analysis to determine early (within 30 days) late (more than days after) complication rates associated tumor RFA. Methods: All treated between January 1, 1996 June 30, 2002 RFA for malignancies were entered into database. Patients evaluated during treatment, throughout the immediate post course, then every 3...
This multi-centre phase II clinical trial is the first prospective evaluation of radioembolisation patients with colorectal liver metastases (mCRC) who failed previous oxaliplatin- and irinotecan-based systemic chemotherapy regimens. Eligible had adequate hepatic, haemopoietic renal function, an absence major hepatic vascular anomalies hepato-pulmonary shunting. Gastroduodenal right gastric arteries were embolised before arterial administration yttrium-90 resin microspheres (median activity,...
Abstract Purpose The aim of the present study was to compare clinical and radiological outcomes between all‐inside single bundle (SB) a modified double‐bundle (DB) anterior cruciate ligament reconstructions (ACLR) at over 5‐year follow‐up. Methods This is an observational, retrospective comparative, two‐centre study. Clinical were evaluated using Lysholm International Knee Documentation Committee (IKDC) scores, tibial translation (ATT) assessed KT‐1000 arthrometer. x‐ray images recorded,...
Abstract Background and Aims Cholangiocarcinoma (CCA), a rare aggressive hepatobiliary malignancy, presents significant clinical management challenges. Despite rising incidence evolving treatment options, prognosis remains poor, motivating the exploration of real‐world data for enhanced understanding patient care. Methods This multicenter study analyzed from 120 metastatic CCA patients at three institutions 2016 to 2023. Kaplan–Meier curves assessed overall survival (OS), while univariate...
Portal vein thrombosis (PVT) is generally recognized as a prognostic factor in HCC. Our purpose to assess and compare the survival of patients with PVT without PVT, after Y-90 Trans-Arterial Radio-Embolization (TARE) unresectable HCC, unresponsive other loco-regional treatments.Between November 2005 2012, resin-based TARE was performed an IRB-approved prospective protocol, on 89 33/89 had remaining 56 were resistant-to-cTACE or underwent downstaging therapy. All studied Multi-Detector...
Abstract Background The clinical observation showed a potential additive effect of anti-PD-1 agents and cetirizine in patients with advanced melanoma. Methods Clinical outcomes concomitant cetirizine/anti-PD-1 treatment stage IIIb–IV melanoma were retrospectively collected, transcriptomic analysis was performed on blood samples obtained at baseline after 3 months treatment. Results Patients treated concomitantly an agent had significantly longer progression-free survival (PFS; mean PFS: 28...
Background Patients with small hepatocellular carcinoma (HCC) are usually treated hepatic resection or percutaneous ethanol injection (PEI). Goals To compare the effects of versus PEI on survival in a matched case–control study. Study single-nodule HCC (≤5 cm) who were (cases) (controls) eligible. Matching criteria date diagnosis, Child–Pugh stage, and age at diagnosis. Kaplan–Meier curve control group was drawn weighing each stratum by inverse its size. Treatments compared stratified Cox's...
Radioembolisation is part of the multimodal treatment hepatocellular carcinoma (HCC) at specialist liver centres. This study analysed impact prior on tolerability and survival following radioembolisation. was a retrospective analysis 325 consecutive patients with confirmed diagnosis HCC, who received radioembolisation yttrium-90 resin microspheres eight European centres between September 2003 December 2009. The decision to treat based clinical judgement multidisciplinary teams. Patients were...
Purpose To assess efficacy and safety of imaging-guided radiofrequency ablation (RFA) Osteoid Osteoma (OO) in both typical atypical sites. Methods materials Between January 2014 March 2019, 102 consecutive percutaneous RFA were performed retrospectively reviewed. The procedures using a bipolar system (Covidien, exposed tip 0.7-1cm), under Computed Tomography (CT) guidance or navigation (Masmec) CT Cone Beam (CBCT) guidance. Patients followed up over 24 months. Clinical success recurrences...
Sodium-Glucose Cotransporter-2 inhibitors (SGLT2i) represent a deep revolution of the therapeutic approach to heart failure (HF), preventing its insurgence but also improving management disease and slowing natural progression. To date, few studies have explored effectiveness SGLT2i and, in particular, Dapagliflozin real-world population. Therefore, this observational prospective study, we evaluated Dapagliflozin's HF population categorized different hemodynamic profiles. From January 2022...