Carmine Izzo

ORCID: 0000-0001-8499-5428
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • COVID-19 Clinical Research Studies
  • Sirtuins and Resveratrol in Medicine
  • Mitochondrial Function and Pathology
  • Cardiovascular Disease and Adiposity
  • Cardiovascular and exercise physiology
  • Heart Rate Variability and Autonomic Control
  • Long-Term Effects of COVID-19
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Health and Disease Prevention
  • Vitamin C and Antioxidants Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Pharmacology and Obesity Treatment
  • Hepatitis B Virus Studies
  • Cardiac Health and Mental Health
  • Hepatitis C virus research
  • Heart Failure Treatment and Management
  • MicroRNA in disease regulation
  • Diabetes Treatment and Management
  • Sphingolipid Metabolism and Signaling
  • Calpain Protease Function and Regulation
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Magnesium in Health and Disease
  • Viral Infections and Outbreaks Research
  • Pancreatic function and diabetes

University of Salerno
2018-2025

Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2024

Chronic kidney disease (CKD) is a global health issue with rising prevalence, affecting 697.5 million people worldwide. It imposes substantial burden, contributing to 35.8 disability-adjusted life years (DALYs) and 1.2 deaths in 2017. The mortality rate for CKD has increased by 41.5% between 1990 2017, positioning it as significant cause of mortality. associated diverse complications, impacting cardiovascular, neurological, nutritional, endocrine aspects. One prominent complication...

10.3390/life14030418 article EN cc-by Life 2024-03-21

Abstract Aims We report the results of a real‐world study based on heart failure (HF) patients' continuous remote monitoring strategy using CardioMEMS system to assess impact this device healthcare outcomes, costs, and management quality life. Methods enrolled seven patients (69.00 ± 4.88 years; 71.43% men) with HF, implanted CardioMEMS, daily monitored optimize both tailored adjustments home therapy and/or hospital infusions levosimendan. recorded clinical, pharmacological, biochemical,...

10.1002/ehf2.14838 article EN cc-by-nc ESC Heart Failure 2024-05-18

Omega-3 fatty acids have been shown to exert several beneficial effects in the prevention of cardiovascular and cerebrovascular diseases. The objective present study was analyze a novel high-load omega-3 lysine complex, AvailOm®, its related constituents mixture AvailOm® with specific vasoactive anthocyanins on vascular function mice resistance artery. Pressure myograph used perform reactivity studies. Nitric oxide oxidative stress were assessed by difluorofluorescein diacetate...

10.3390/antiox11050896 article EN cc-by Antioxidants 2022-04-30

Background High blood pressure (BP) has long been recognized as a major health threat and, particularly, risk factor for stroke, cardiovascular disease, and end-organ damage. However, the identification of novel, alternative, integrative approach control BP protection is still needed. Methods Results Sixty-nine uncontrolled hypertension patients, aged 40 to 68 years, on antihypertensive medication were enrolled in 2 double-blind studies. Forty-five randomized placebo or new nutraceutical...

10.1161/jaha.119.014923 article EN cc-by-nc-nd Journal of the American Heart Association 2020-02-21

High glucose–induced endothelial dysfunction is an important pathological feature of diabetic vasculopathy. While genome-wide studies have identified association between type 2 diabetes mellitus (T2DM) and increased expression a C2 calcium-dependent domain containing 4B (C2CD4B), no study has yet explored the possible direct effect C2CD4B on vascular function. Vascular reactivity were conducted using pressure myograph, nitric oxide oxidative stress assessed through difluorofluorescein...

10.3390/antiox13010101 article EN cc-by Antioxidants 2024-01-14

(1) Background: The emergency linked to the spread of COVID-19 in Italy has led inevitable consequences on penitentiary system. risks this prisons is mainly related problem persistent overcrowding that makes social distancing difficult and isolation any contagion hard arrange. Department Protection for Adults Minors ASL Salerno Criminal Area taken steps order perform screening operations minimize prisoners operators. (2) Methods: We conducted a two-phase observational study. In first phase,...

10.3390/ijerph17218033 article EN International Journal of Environmental Research and Public Health 2020-10-31

Sacubitril/valsartan (Sac/Val) reduces mortality in patients with heart failure reduced ejection fraction (HFrEF) compared to enalapril. However, its effects on functional capacity remain uncertain; consequently, we sought compare Sac/Val vs. standard medical therapy, terms of prognostically significant CPET parameters, HFrEF during a long follow-up period. We conducted single-center, observational study an HF clinic; specifically, retrospectively identified that 12 switched and 13 managed...

10.3390/life13051174 article EN cc-by Life 2023-05-12

Sodium-Glucose Cotransporter-2 inhibitors (SGLT2i) represent a deep revolution of the therapeutic approach to heart failure (HF), preventing its insurgence but also improving management disease and slowing natural progression. To date, few studies have explored effectiveness SGLT2i and, in particular, Dapagliflozin real-world population. Therefore, this observational prospective study, we evaluated Dapagliflozin's HF population categorized different hemodynamic profiles. From January 2022...

10.1186/s12933-024-02515-5 article EN cc-by-nc-nd Cardiovascular Diabetology 2024-11-22

Latent Mycobacterium tuberculosis infection (LTBI) and active in prisoners are higher than the general population two public health concerns, especially low- middle-income countries. We conducted a cross-sectional study to determine prevalence factors associated with LTBI among inmate detained three Southern Italian penitentiaries. Tuberculin intradermal reaction skin test was performed on inmates who agreed participate study. In case of positivity, QuantiFERON-TB performed. those positive...

10.3390/healthcare10020386 article EN Healthcare 2022-02-18
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