A5073406992- Endoplasmic Reticulum Stress and Disease
- Antioxidant Activity and Oxidative Stress
- Lipid Membrane Structure and Behavior
- Circular RNAs in diseases
- Cardiovascular Function and Risk Factors
- Hops Chemistry and Applications
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Pharmacology and Obesity Treatment
- MicroRNA in disease regulation
- Phytochemicals and Antioxidant Activities
- Nitric Oxide and Endothelin Effects
- Sphingolipid Metabolism and Signaling
- Extracellular vesicles in disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- RNA regulation and disease
- Ginseng Biological Effects and Applications
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
University of Salerno
2022-2025
In recent decades, as a result of rising mortality rates due to cardiovascular diseases (CVDs), there has been growing urgency find alternative approaches conventional pharmaceutical treatment prevent the onset chronic diseases.
High glucose–induced endothelial dysfunction is an important pathological feature of diabetic vasculopathy. While genome-wide studies have identified association between type 2 diabetes mellitus (T2DM) and increased expression a C2 calcium-dependent domain containing 4B (C2CD4B), no study has yet explored the possible direct effect C2CD4B on vascular function. Vascular reactivity were conducted using pressure myograph, nitric oxide oxidative stress assessed through difluorofluorescein...
A representative mechanism evoked by the B1 subfraction at vascular levels in resistance arteries. ECs: endothelial cells; SMCs: smooth muscle cells.
Background and Purpose Accumulating evidence suggests circulating microRNAs (miRNAs) are important regulators of biological processes involved in COVID‐19 complications. We sought to assess whether miRNAs associated with clinical phenotype outcome. Experimental Approach To discover signatures disease severity mortality, miRNA quantification was performed on plasma samples collected at hospital admission from a cohort 106 patients mild or severe COVID‐19. Variable importance projection...
Abstract Long-term use of the vitamin K antagonist (VKA) warfarin, has been shown to accelerate vascular and valvular calcification both in rodents humans. Increasing evidence suggests that endothelium contributes via endothelial-mesenchymal transition (EndMT). However, additional research is warranted elucidate signaling mechanisms involved. In last decade, a prominent role for sortilin demonstrated cardiovascular calcification. Moreover, we recently increase promotes endothelial...