- Pituitary Gland Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Diabetes Management and Education
- Pharmacological Effects and Toxicity Studies
- Meningioma and schwannoma management
- Diabetes Treatment and Management
- Adrenal Hormones and Disorders
- Metabolism, Diabetes, and Cancer
- Breast Lesions and Carcinomas
- Mitochondrial Function and Pathology
- Genetic Syndromes and Imprinting
- Intestinal Malrotation and Obstruction Disorders
- Electrolyte and hormonal disorders
- Cancer, Hypoxia, and Metabolism
- Head and Neck Surgical Oncology
- Cytokine Signaling Pathways and Interactions
- HIV/AIDS drug development and treatment
- Chronic Disease Management Strategies
- Thyroid Disorders and Treatments
- Magnesium in Health and Disease
- Parathyroid Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Patient Safety and Medication Errors
Tan Tock Seng Hospital
2014-2024
Nanyang Technological University
2021-2024
Abstract Background Interleukin 4 (IL-4), increased in tuberculosis infection, may impair bacterial killing. Blocking IL-4 confers benefit animal models. We evaluated safety and efficacy of pascolizumab (humanized anti–IL-4 monoclonal antibody) as adjunctive treatment. Methods Participants with rifampicin-susceptible pulmonary received a single intravenous infusion or placebo, standard 6-month Pascolizumab dose successive cohorts: (1) nonrandomized 0.05 mg/kg (n = 4); (2) 0.5 (3) randomized...
Abstract Aims This study aims to investigate the relationship between long‐term visit‐to‐visit within‐person HbA1c variability and hospitalisation outcomes in adults with type 2 diabetes (T2D). Methods We conducted a cohort at tertiary hospital Singapore involving people aged 21 101 years T2D who had ≥3 tests over years. was assessed using coefficient of variation (CV), independent mean (VIM) score (HVS). A 1‐year follow‐up performed after last measurement identify all‐cause potentially...
Brown adipose tissue (BAT) controls metabolic rate through thermogenesis. As its regulatory factors during the transition from hyperthyroidism to euthyroidism are not well established, our study investigated relationships between supraclavicular brown (sBAT) activity and physiological/metabolic changes with in thyroid status.Participants newly diagnosed Graves' disease were recruited. A thionamide antithyroid drug (ATD) such as carbimazole (CMZ) or thiamazole (TMZ) was prescribed every case....
In recent decades, the prevalence of diabetes has been increasing in many countries, including Singapore.1–3 Consequently, a large number hospital admissions are related either directly or indirectly to one its complications. Approximately 30% our tertiary (based on internal audit data). Insulin therapy is required for management hyperglycemia patients with without diabetes. The main danger insulin use life-threatening hypoglycemia. Insulin five “high-alert” medications identified by Joint...
Non-islet cell tumor hypoglycemia (NICTH) is an uncommon condition, of which only a few cases caused by malignant phyllodes the breast have been reported. We describe case NICTH secondary to with good response glucocorticoid therapy.
One of the laboratory tests recommended by American Diabetes Association (ADA) to screen for diabetes mellitus (DM) is HbA1c, and it particularly suitable segments population that cannot or are unwilling fast a screening test. The aim this study was determine whether HbA1c would be useful tool DM in real-world setting if ADA guidelines repeat testing confirm diagnosis strictly adhered to.A retrospective database performed extracting demographic data from chronic disease registry collects on...
Abstract Disclosure: Y. Koh: None. D.E. Chew: T.P. Quek: Introduction: Parathyroid carcinoma is a rare form of malignancy. An intrathyroidal location parathyroid further complicates the diagnosis as it may be mistakenly presumed to thyroid origin instead. We present case report an which was diagnosed post-total thyroidectomy. Clinical case: A 72-year-old lady found have mass after presenting with unintentional weight loss and chronic constipation. Ultrasound neck showed 4.0 x 2.9cm markedly...
Background In the evaluation of Cushing’s syndrome (CS), oral contraceptives may lead to false-positive results by raising serum levels cortisol-binding globulin (CBG). Clinical Case An 18-year old Chinese lady presented with weight gain, irregular menses and hirsutism. History was unremarkable for hypothyroidism, hyperprolactinemia, eating disorders, exogenous steroid use. On examination, she overweight (body mass index (BMI) 26.9 kg/m2) rounded facies, hirsutism dorsal cervical fat pad....
Abstract Introduction: Trimethoprim-sulfamethoxazole (TMP-SMX) is a commonly used antibiotic. We present case of severe hyponatremia and Type 4 renal tubular acidosis (functional hypoaldosteronism) in patient treated with TMP-SMX. Clinical Case: A 62 year old gentleman hypertension, dyslipidemia surgically repaired abdominal aortic aneurysm developed an graft infection. He was admitted to hospital for acute right lower limb ischemia embolic phenomena, underwent surgical explantation....
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)