A5101632616- Tuberculosis Research and Epidemiology
- Vaccine Coverage and Hesitancy
- Hearing, Cochlea, Tinnitus, Genetics
- Influenza Virus Research Studies
- HIV/AIDS Impact and Responses
- Pneumonia and Respiratory Infections
- Air Quality and Health Impacts
- Hearing Loss and Rehabilitation
- Occupational exposure and asthma
- Occupational and environmental lung diseases
- Hepatitis C virus research
- Ear Surgery and Otitis Media
Nantong University
2023-2024
Affiliated Hospital of Nantong University
2023-2024
Nantong Science and Technology Bureau
2024
Abstract Background Pneumoconiosis, a chronic disease stemming from prolonged inhalation of dust particles, stands as significant global burden occupational diseases. This study aims to investigate the survival outcomes pneumoconiosis patients in Huangshi city, China, while also evaluating on afflicted patients. Methods Data for this were sourced Center Disease Control and Prevention. Survival analyses conducted employing life tables Kaplan-Meier method. The Cox proportional hazards models...
Introduction Given the ageing epidemic of tuberculosis (TB), China is facing an unprecedented opportunity provided by first clinically approved next-generation TB vaccine Vaccae, which demonstrated 54.7% efficacy for preventing reactivation from latent infection in a phase III trial. We aim to assess population-level health and economic impacts introducing Vaccae vaccination inform policy-makers. Methods evaluated potential national programme initiated 2024, assuming 20 years protection, 90%...
Background While global newborn hearing screening programmes (NHSP) are far from the optimal level, combined and genetic has emerged as an innovative approach of early healthcare interventions. There is a clear need for economic evaluation to establish whether deafness gene (NDGS), currently mandated by many cities in China, good investment. Methods A decision-tree model was constructed simulate hypothetical 10-million Chinese cohort over lifetime with three strategies: (1) no screening, (2)...
Introduction Tuberculosis (TB) is a major global health issue, particularly, in India and South Africa. We aim to evaluate the potential of new TB vaccine, Vaccae, enhance control by integrating with active case finding (ACF) strategies these regions. Methods Using age-structured dynamic models, we projected epidemiological economic outcomes combining Vaccae vaccination ACF over 27 years. In India, four age-targeted were analysed: (1) adolescent (15 years), (2) young adult (AYA, 15–34 (3)...
Abstract Background China faces high burden of multidrug-resistant or rifampicin-resistant tuberculosis (MDR/RR-TB). We aimed to evaluate the impacts Vaccae vaccination and enhanced drug-resistant TB (DR-TB) management strategies. Methods Using a compartmental model calibrated with national data, we evaluated 9 interventions: DR-TB (S1); for those latent infection, targeting specific age groups (S2: adolescents, S3: adolescents young adults, S4: working-age S5: elderly); combined strategies...
This study used a calibrated mathematical model to evaluate age-specific tuberculosis (TB) vaccination strategies, for drug-resistant (DR)-TB management in China. Prioritizing elderly significantly reduced multidrug-resistant or rifampicin-resistant TB incidence and mortality, while avoiding the need second-line treatment, offering promising approach mitigate DR-TB burden by 2050.