- Pregnancy and preeclampsia studies
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Prenatal Screening and Diagnostics
- Congenital Heart Disease Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Gestational Trophoblastic Disease Studies
- Barrier Structure and Function Studies
- Urological Disorders and Treatments
- Ectopic Pregnancy Diagnosis and Management
- Innovative Teaching and Learning Methods
- Maternal and fetal healthcare
- Pediatric Urology and Nephrology Studies
- Cervical Cancer and HPV Research
- Pregnancy and Medication Impact
- Systemic Lupus Erythematosus Research
- Birth, Development, and Health
- Alzheimer's disease research and treatments
- Cardiovascular Issues in Pregnancy
- Cleft Lip and Palate Research
- Congenital heart defects research
Kagawa University
2016-2025
Kagawa University Hospital
2023
Institute Of Perinatology Obstetrics And Gynaecology
2008-2022
Tokushima University
2002-2006
Shikoku University
1995-2002
Recent advances in three-/four-dimensional (3D/4D) ultrasound, such as HDlive Flow, provide the potential to evaluate more precisely fetal and placental circulations1-5 gynecological disorders6-10. Flow silhouette mode is latest technology demonstrate blood flow with vitreous-like clarity. This technique has ability delineate vessel walls, while presenting lumen semitransparent. We present our experience of imaging normal abnormal cardiac structures, reconstructed using spatiotemporal image...
Abstract Background This study aimed to investigate the effect of glucocorticoid doses on adverse pregnancy outcomes (APOs) in women complicated by systemic lupus erythematosus (SLE). Methods We investigated 74 pregnancies SLE or SLE-dominant mixed connective tissue disease. The were managed from conception delivery our institution. retrospectively evaluated whether mean dose during is associated with APOs, including preterm birth (PB), low weight (LBW), and light-for-date (LFD). also...
There have been a few reports about 3-D sonographic observation of fetal movements using dynamic sonography. However, sonography is not real-time, the frame rate being in region 4-6 frames per second depending on size interest and number lines employed. Recently, new faster sonography, which acquires up to 28 second, has become available. Using this system, we studied full range facial expressions during pregnancy.A total 17 normal fetuses 16 pregnancies (15 singletons one twin) at 20-38...
Circumvallate placenta is a morphological placental abnormality in which the chorionic plate smaller than basal plate, resulting folding back of and fetal membranes towards surface. There have been numerous reports on antenatal diagnosis circumvallate using two-dimensional (2D) three-dimensional ultrasound1-4, however, to best our knowledge, this first present HDlive silhouette mode imaging for prenatal placenta. A 26-year-old pregnant Japanese primigravida was referred hospital at 14 + 5...
Abstract This study aimed to evaluate the ethnic difference in fetal behavior between Asian and Caucasian populations. Fetal was assesed by Kurjak’s antenatal neurodevelopmental test (KANET) using four-dimensional (4D) ultrasound 28 38 weeks of gestation. Eighty-nine Japanese (representative Asians) seventy-eight Croatian Caucasians) pregnant women were studied. The total value KANET score values each parameter (eight parameters) compared. normal both populations, but there a significant...
Abstract Background The early identification of developmental concerns requires understanding individual differences that may represent signs neurodevelopmental conditions. However, few studies have longitudinally examined how child and maternal factors interact to shape these characteristics. Objective We aim identify from the perinatal infant periods associated with characteristics precede formal diagnoses propose a method for evaluating in trajectories. Methods A prospective longitudinal...
Abstract Aim: The purpose of this study was to present our first experience normal embryonic brain vesicle shapes in the early trimester pregnancy, reconstructed by three‐dimensional (3D) volume‐rendered imaging using inversion mode. Methods: Twenty‐three women who were between 7.4 and 9.7 weeks gestation studied 3D ultrasound with a mechanical 3.7–9.3 or 4.5–11.9 MHz transvaginal probe. In order clarify anatomical correlation fetal vesicles, mode used. Results: One patient at excluded from...
We present our experience of using transvaginal three/four-dimensional (3D/4D) color Doppler with glass-body rendering mode and spatiotemporal image correlation (STIC) software to construct an persistent truncus arteriosus in the first trimester pregnancy. There have been numerous reports on antenatal diagnosis two-dimensional (2D) grayscale echocardiography, multiplanar display 3D/4D ultrasound1-3; however, best knowledge, this is report STIC. A 37-year-old pregnant Japanese woman, gravida...
Oxidative stress in diabetes mellitus has recently received increasing attention as it been proven to be associated with the development of diabetic vascular complications. Our aim was examine whether microvascular changes, including oxidative damage, were induced brains animals.The expression 8-hydroxy-2'-deoxyguanosine (8-OHdG), a marker DNA binding cationized ferritin, for evaluating endothelial glycocalyx, cells capillaries and permeability intravenously injected horseradish peroxidase...
We previously reported that the blood-brain barrier (BBB) function was impaired in vessels hippocampus 3-month-old stroke-prone spontaneously hypertensive rats (SHRSP). In this study, we examined gene and protein expressions of P-glycoprotein, a representative efflux transporter cerebral vessels, BBB-damaged hippocampal SHRSP Wistar Kyoto (WKY) as controls, to clarify roles vessels.The expression P-glycoprotein cortical samples by real-time quantitative reverse transcriptase-polymerase chain...
Abstract Objective To evaluate fetal behavioral differences between singleton and twin fetuses before 20 weeks of gestation using four-dimensional (4D) ultrasound. Methods 4D ultrasound was used to examine movements in 58 48 normal at 12–19 weeks. The frequencies eight were assessed through 15-min recordings. divided into two gestational age groups (12–13 14–19 weeks) the changes with advancing versus fetuses. Results Arm general most frequent fetuses, whereas only movement significantly...