- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Diabetes Management and Research
- Diabetes Treatment and Management
- Hydrogels: synthesis, properties, applications
- Sexual function and dysfunction studies
- Health Systems, Economic Evaluations, Quality of Life
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Cardiovascular Syncope and Autonomic Disorders
- Coronary Interventions and Diagnostics
- Obstructive Sleep Apnea Research
- Occupational Health and Safety Research
- Reproductive Health and Contraception
- Bladder and Urothelial Cancer Treatments
- Cell Adhesion Molecules Research
- Pancreatic function and diabetes
- Metal complexes synthesis and properties
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Osteoarthritis Treatment and Mechanisms
- Adolescent Sexual and Reproductive Health
- Pharmacology and Obesity Treatment
- Occupational exposure and asthma
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Vanderbilt University
2024-2025
University of Hertfordshire
2011
GlaxoSmithKline (India)
2003
Health Outcomes Solutions (United States)
2003
Wellcome Library
1998
Four hundred and eleven subjects who either reported to Occupational Health at onset of influenza or influenza-like illness (I/ILI) symptoms on return work completed questionnaires entry the study after 28 days. On average they were incapacitated confined bed for 2.4 days, missing 2.8 days from per episode illness. work, reduced effectiveness inability resume normal activity until a mean 3.5 symptoms. Each participant 6.5 I/ILI There was positive correlation between number (r = 0.24) missed...
The topics covered in this section relate to areas of considerable interest for urologists everywhere. UrEpik study is introduced the ‘Comments’ and results will appear a series papers published over next few months. They give new insight into many aspects LUTS. Authors from London investigate place urodynamics evaluation patients with symptoms overactive bladder. found that such apparently normal urodynamic findings often respond equally well antimuscarinic therapy as do those positive...
OBJECTIVE To report a large‐scale multinational investigation of lower urinary tract symptoms (LUTS) and sexual function, designed to investigate the independent association between them, as recent small‐scale epidemiological studies suggest an benign prostatic hyperplasia dysfunction; both conditions are strongly associated with age no study has been able exclude confounding factor in this relationship. SUBJECTS AND METHODS Culturally linguistically validated versions standard...
OBJECTIVES To report the results of prevalence and health status associated with male urinary incontinence (UI) in a population‐based, multicentre study four countries, to assess epidemiology this condition. SUBJECTS AND METHODS A standard questionnaire asking about frequency amount urine loss, use pads stress incontinence, was used measure UI among men countries (Boxmeer, The Netherlands; Auxerre, France; Birmingham, UK; Seoul, Korea). Self‐reported leakage also recorded, details visits...
To assess the hypothesis that as lower urinary tract symptoms (LUTS) increase in severity, impact measured by BPH index (BII) would also increase.The UREPIK survey collected information on this relationship from men and their partners Netherlands, Korea, France UK. Culturally linguistically validated versions of three standard questionnaires, SF-12, BII International Prostate Symptom Score (IPSS) were used to distribution health status. Stratified random samples aged 40-79 years each...
Abstract Osteoarthritis (OA) and rheumatoid arthritis (RA) are joint diseases that associated with pain lost quality of life. No disease modifying OA drugs currently available. RA treatments better established but not always effective can cause immune suppression. Here, an MMP13-selective siRNA conjugate was developed that, when delivered intravenously, docks onto endogenous albumin promotes preferential accumulation in articular cartilage synovia joints. MMP13 expression diminished upon...
Osteoarthritis and rheumatoid arthritis are debilitating joint diseases marked by pain, inflammation cartilage destruction. Current osteoarthritis treatments only relieve symptoms, while therapies can cause immune suppression provide variable efficacy. Here we developed an optimized small interfering RNA targeting matrix metalloproteinase 13 for preferential delivery to arthritic joints. Chemical modifications in a stabilizing 'zipper' pattern improved resistance degradation, two independent...
Peripheral artery disease is commonly treated with balloon angioplasty, a procedure involving minimally invasive, transluminal insertion of catheter to the site stenosis, where inflated open blockage, restoring blood flow. However, peripheral angioplasty has high rate restenosis, limiting long-term patency. Therefore, sometimes paired delivery cytotoxic drugs like paclitaxel reduce neointimal tissue formation. We pursue intravascular drug strategies that target underlying cause restenosis -...
This cost analysis, based on the results of GINGER study, aimed to investigate whether an intensified insulin regimen is better value than a 2 injection per day conventional regimen. was 52 week multi-national study in 310 T2D patients for average 5 years with poor glycaemic control. It compared mealtime rapid-acting glulisine (IGL) and glargine (IG) once daily injections pre-mixed insulin. Use IGL/IG resulted change HbA1C from baseline endpoint −1.31% −0.80% Costs were calculated UK NHS...