Siqin Li

ORCID: 0009-0003-0161-8689
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About
Contact & Profiles
Research Areas
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Cancer Research and Treatments
  • Cancer, Stress, Anesthesia, and Immune Response
  • Thin-Film Transistor Technologies
  • ZnO doping and properties
  • Immune Cell Function and Interaction
  • Advanced Memory and Neural Computing
  • Transition Metal Oxide Nanomaterials
  • Thermochemical Biomass Conversion Processes
  • Immunotherapy and Immune Responses
  • CCD and CMOS Imaging Sensors
  • Microbial Fuel Cells and Bioremediation
  • Reinforcement Learning in Robotics
  • Membrane Separation Technologies
  • Ferroelectric and Negative Capacitance Devices
  • Bone Metabolism and Diseases
  • Neuroscience and Neural Engineering
  • Copper-based nanomaterials and applications
  • Anaerobic Digestion and Biogas Production
  • Semiconductor materials and devices
  • Advanced oxidation water treatment
  • Cancer Cells and Metastasis
  • MicroRNA in disease regulation
  • Algal biology and biofuel production

Nanjing Tech University
2023-2025

Inner Mongolia Medical University
2025

East China Normal University
2023-2025

Zhejiang University
2018-2024

Shanghai Cancer Institute
2024

Fudan University Shanghai Cancer Center
2023-2024

State Key Laboratory of Genetic Engineering
2023-2024

Fudan University
2020-2024

Cancer Institute (WIA)
2024

Shanghai Medical College of Fudan University
2024

Abstract Artificial synapse devices are dedicated to overcoming the von Neumann bottleneck. Adopting light signals in visual information processing and computing is vital for developing next‐generation artificial neuromorphic systems. A strategy construct all‐optically controlled synaptic based on full oxides with amorphous ZnAlSnO/SnO heterojunction a two‐terminal planar configuration proposed. All behaviors operated visible optical pathway, excitatory under red (635 nm) inhibitory green...

10.1002/adfm.202312444 article EN Advanced Functional Materials 2023-11-27

ZnO is a significant semiconductor material with the characteristics of direct band gap, large exciton binding energy, and easy growth high-quality nanostructures, it widely used in various fields. However, obtaining p-type has become obstacle to wide application ZnO. The research on p-ZnO started several decades ago regarded as focus. Many researchers have obtained by chemical vapor deposition (CVD) physical (PVD). To obtain p-ZnO, some "better" techniques improve crystal quality mobility...

10.1021/acsaelm.3c00515 article EN ACS Applied Electronic Materials 2023-08-07

Triple-negative breast cancer (TNBC) is an aggressive subtype of with limited therapeutic options. IL1 receptor type 2 (IL1R2) promotes tumor-initiating cell (BTIC) self-renewal and tumor growth in TNBC, indicating that targeting it could improve patient treatment. In this study, we observed IL1R2 blockade strongly attenuated macrophage recruitment the polarization tumor-associated macrophages (TAM) to inhibit BTIC CD8+ T-cell exhaustion, which resulted reduced burden prolonged survival TNBC...

10.1158/0008-5472.can-23-3429 article EN Cancer Research 2024-04-24

Tumor-resident microbiota in breast cancer promotes initiation and malignant progression. However, targeting to improve the effects of therapy has not been investigated detail. Here, we evaluated composition tumors found that enterotoxigenic Bacteroides fragilis (ETBF) was highly enriched patients who did respond taxane-based neoadjuvant chemotherapy. ETBF, albeit at low biomass, secreted toxic protein BFT-1 promote cell stemness chemoresistance. Mechanistic studies showed directly bound...

10.1093/procel/pwae005 article EN cc-by Protein & Cell 2024-02-29

Neuromorphic computing, which mimics brain function, can address the shortcomings of "von Neumann" system and is one critical components next-generation computing. The use light to stimulate artificial synapses has advantages low power consumption, latency, high stability. We demonstrate amorphous InAlZnO-based light-stimulated synaptic devices with a thin-film transistor structure. exhibit fundamental properties, including excitatory postsynaptic current, paired-pulse facilitation (PPF),...

10.1021/acsami.2c14029 article EN ACS Applied Materials & Interfaces 2022-10-04

Amorphous Nb2O5 is proposed as the resistive switching layer for conductive bridge random access memory. The device fabricated with top Cu and bottom Au electrodes, which at a fully room temperature process, exhibiting excellent performance an on/off ratio of up to 105 ultralow operating voltage. multilevel characteristic can be rationally demonstrated by changing compliance current in device. Each level resistance state uniform distinguishable read windows. reset voltage reduces...

10.1021/acsmaterialslett.2c01218 article EN ACS Materials Letters 2023-04-04

We present JueWu-SL, the first supervised-learning-based artificial intelligence (AI) program that achieves human-level performance in playing multiplayer online battle arena (MOBA) games. Unlike prior attempts, we integrate macro-strategy and micromanagement of MOBA-game-playing into neural networks a supervised end-to-end manner. Tested on Honor Kings, most popular MOBA at present, our AI performs competitively level High King players standard 5v5

10.1109/tnnls.2020.3029475 article EN IEEE Transactions on Neural Networks and Learning Systems 2020-11-04

As a systemic skeletal dysfunction, osteoporosis (OP) is characterized by low bone mass and microarchitectural damage. The global incidences of OP are high.Data were retrieved from databases like Gene Expression Omnibus (GEO), GeneCards, Search Tool for the Retrieval Interacting Genes/Proteins (STRING), Profiling Interactive Analysis (GEPIA2), other databases. R software (version 4.1.1) was used to identify differentially expressed genes (DEGs) perform functional analysis. Least Absolute...

10.3389/fimmu.2022.987937 article EN cc-by Frontiers in Immunology 2022-10-13

The gradual switching in a-ZATO indicates that the filaments generated by reorganization of oxygen vacancies are more conductive than initial LRS. special relaxation model reveals diffusion these orthogonal directions.

10.1039/d3mh01035j article EN Materials Horizons 2023-01-01

Abstract Amorphous oxide semiconductors (AOS) have unique advantages in transparent and flexible thin film transistors (TFTs) applications, compared to low-temperature polycrystalline-Si (LTPS). However, intrinsic AOS TFTs are difficult obtain field-effect mobility ( μ FE ) higher than LTPS (100 cm 2 /(V·s)). Here, we design ZnAlSnO (ZATO) homojunction structure = 113.8 /(V·s). The device demonstrates optimized comprehensive electrical properties with an off-current of about 1.5 × 10 –11 A,...

10.1088/1674-4926/44/5/052101 article EN Journal of Semiconductors 2023-05-01
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