A5054471785- Global Maternal and Child Health
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Child Nutrition and Feeding Issues
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Global Health Care Issues
- Emergency and Acute Care Studies
- Agriculture and Rural Development Research
- Influenza Virus Research Studies
- Food Security and Health in Diverse Populations
- Respiratory viral infections research
- Delphi Technique in Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Animal Diversity and Health Studies
- Nutrition and Health in Aging
- HIV/AIDS Impact and Responses
- Respiratory Support and Mechanisms
- Biomedical and Engineering Education
- Non-Invasive Vital Sign Monitoring
- Ultrasound in Clinical Applications
- Healthcare Systems and Reforms
- Nosocomial Infections in ICU
Centre de recherche en Epidémiologie et Santé des Populations
2023-2024
Université de Toulouse
2023-2024
Terre des Hommes
2024
Université Toulouse III - Paul Sabatier
2022-2024
Inserm
2022-2024
Hôpital Bonnet
2024
Institut Pasteur de Dakar
2018-2021
With the growing success of controlling malaria in Sub-Saharan Africa, incidence fever due to is decline, whereas proportion patients with non-malaria febrile illness (NMFI) increasing. Clinical diagnosis NMFI hampered by unspecific symptoms, but early a key factor for both better patient care and disease control. The aim this study was determine arboviral aetiologies low resource settings, using mobile laboratory based on recombinase polymerase amplification (RPA) assays. panel tests...
Abstract Background Influenza is a major cause of morbidity and mortality in Africa. However, lack epidemiological data remains for this pathology, the performances influenza-like illness (ILI) case definitions used sentinel surveillance have never been evaluated Senegal. This study aimed to i) assess performance three different ILI definitions, adopted by WHO, USA-CDC (CDC) European-CDC (ECDC) ii) identify clinical factors associated with positive diagnosis order develop an algorithm fitted...
Introduction Hypoxemia is an important contributor to child mortality, particularly in low-resource settings where diagnostic tools are scarce. The AIRE project introduced pulse oximeters (POs) into 202 primary healthcare centres (PHCs) Burkina Faso, Guinea, Mali, and Niger, integrating them the Integrated Management of Childhood Illness (IMCI) guidelines. This initiative aimed strengthen capacities for identifying hypoxemia improve care management critically ill children under five. study...
Background: The Integrated Management of Childhood Illness (IMCI) guidelines guide the healthcare workers (HCW) referral decision under-5 children at primary health centres (PHCs). AIRE project has implemented routine Pulse Oximeter (PO) use into IMCI consultations PHCs in West Africa (Burkina Faso, Guinea, Mali and Niger) to improve diagnosis severe cases. We analysed frequency correlates missed opportunities for hospitalisation (MOH) pneumonia Methods: All aged 2-59 months attending...
The AIRE operational project will evaluate the implementation of routine Pulse Oximeter (PO) use in integrated management childhood illness (IMCI) strategy for children under-5 primary health care centers (PHC) West Africa. introduction PO should promote accurate identification hypoxemia (pulse blood oxygen saturation Sp02 < 90%) among all severe IMCI cases (respiratory and non-respiratory) to prompt their effective case (oxygen, antibiotics other required treatments) at hospital. We seek...
Abstract The main objective of this project was to compare in the field conditions two strategies re‐nutrition children with moderate acute malnutrition (MAM) aged from 6 24 months, targeting microbiota comparison a standard regimen. A three‐arm, open‐label, pragmatic randomised trial conducted four countries (Niger, CAR, Senegal and Madagascar). Children received for 12 weeks either fortified blended flour (FBF control) = arm 1, or FBF + azithromycin (oral suspension 20 mg/kg/day daily...
ABSTRACT Background Despite the Integrated Management of Childhood Illness (IMCI) implemented at primary health centres (PHC) level, under-5 mortality remains high in sub-Saharan Africa. To improve diagnosis and management severe hypoxaemia, AIRE project systematic use pulse oximeters (PO) into IMCI consultations PHCs Burkina Faso, Guinea, Mali Niger. We described intervention sites, measure their capacity to offer IMCI-care prior implementation. Methods A cross-sectional quantitative survey...
Knowing the burden of influenza is helpful for policy decisions. Here we estimated contribution influenza-like illness (ILI) visits associated with laboratory-confirmed among all clinic in a Senegal sentinel network. ILI data from ten sites were collected January 2013 to December 2015. was defined as an axillary measured fever more than 37.5 °C cough or sore throat. Collected nasopharyngeal swabs tested viruses by rRT-PCR. Influenza-associated influenza. For disease estimation, used all-case...
The aim of this open-label, randomized controlled trial conducted in four African countries (Madagascar, Niger, Central Republic, and Senegal) is to compare three strategies renutrition for moderate acute malnutrition (MAM) children based on modulation the gut microbiota with enriched flours alone, prebiotics or coupled antibiotic treatment. To be included, aged between 6 months 2 years are preselected mid-upper-arm circumference (MUAC) included a weight-for-height Z-score (WHZ) − 3 standard...
<title>Abstract</title> <italic>Background</italic>. Under-five mortality remains high in West Africa, where sick children are expected to first attend the primary health care before being referred a hospital if necessary. However, little is known about how families navigate between home and higher levels of meet their children’s needs, despite multiple barriers (including social, financial, geographical accessibility). We analysed pathways aged 0-5 years they presented district with serious...
Introduction: To better identify illnesses with severe hypoxemia in children aged under-5 years, the AIRE project has implemented routine use of a Pulse Oximeter (PO) into Integrated Management Childhood Illness (IMCI) guidelines at primary health centers (PHC) Burkina Faso, Guinea, Mali, and Niger. We aimed to measure understand acceptability among healthcare worker.s (HCW) children.s families (CF) using PO these contexts. Methods: Based on an original conceptual framework, we conducted...
Abstract Introduction Out-of-pocket payments persist, limiting access to care in Africa. The AIRE project evaluated the implementation of pulse oximetry integrated with Integrated Management Childhood Illness (IMCI) at Primary Healthcare Centres (PHCs) Burkina Faso and Niger (total exemption policy) Mali Guinea (partial policy). We measured households’ out-of-pocket expenditures for children under-5 years analyzed associated factors. Methods Between 06/2021-05/2022, five non-severe severe...
To describe antibiotic prescribing practices using the WHO AWaRe (
Dengue fever is the most common arboviral infection worldwide. Its epidemiology in Africa not yet fully understood due to lack of awareness, presence other dengue-like febrile diseases, and insufficient laboratory capabilities. This paper reports on import dengue virus serotype 2 case from Côte d'Ivoire Senegal West Africa. Phylogenetic analysis based full-length genome sequence revealed that isolate clustered with strains cosmopolitan genotypes Burkina Faso outbreak 2016 those ongoing...
ABSTRACT Fever is one of the most common reasons for pediatric consultation in Africa. Malaria incidence has now dropped considerably, yet etiologies non-malarial febrile diseases are poorly documented. This pilot study aimed to 1) identify pathogens potentially associated with fever children younger than 10 years suburbs Dakar and 2) describe epidemiological characteristics these patients. During period, all eligible (< age, body temperature ≥ 38°C, negative result malaria rapid...
Abstract Background The Integrated Management of Childhood Illness (IMCI) guidelines is a symptom-based algorithm guiding healthcare workers in resource-limited countries to identify critically ill children under-5 primary centre (PHC). Hypoxemia, life-threatening event, often clinically underdiagnosed. AIRE project has implemented the routine use Pulse Oximeter (PO) IMCI consultations improve diagnosis severe hypoxemia (SpO 2 < 90%) and management cases at PHC level Burkina Faso, Guinea,...
Abstract Background The AIRE project has implemented routine Pulse Oximeter (PO) use in Integrated Management of Childhood Illness (IMCI) consultations to improve the diagnosis and care management severe illnesses primary health centre (PHC) Burkina Faso, Guinea, Mali Niger. We analysed cases according hypoxemia, determinants their Day-14 mortality. Methods All children under-5 attending IMCI using PO classified as (severe or with hypoxemia: SpO2<90%) were enrolled at 16 research PHCs...