A5028909828- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Malaria Research and Control
- Viral Infections and Outbreaks Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Cervical Cancer and HPV Research
- Zoonotic diseases and public health
- Parasites and Host Interactions
- Fire effects on ecosystems
- Influenza Virus Research Studies
- Respiratory viral infections research
- Irrigation Practices and Water Management
- Digital Imaging for Blood Diseases
- Dengue and Mosquito Control Research
- Food Drying and Modeling
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- Hepatitis B Virus Studies
- Genital Health and Disease
- Gene expression and cancer classification
- Vector-Borne Animal Diseases
- Garlic and Onion Studies
- Vibrio bacteria research studies
Institut Pasteur de Dakar
2016-2025
Hôpital Européen
2023
Hôpital Européen Georges-Pompidou
2023
Ministère de la Santé Publique et Action Sociale
2023
Université Gaston Berger
2014
Institut Pasteur
2014
An urban epidemic of dengue in Senegal during 2009 affected 196 persons and included 5 cases hemorrhagic fever 1 fatal case shock syndrome. Dengue virus serotype 3 was identified from all patients, Aedes aegypti mosquitoes were as the primary vector virus.
Rift Valley fever virus (RVFV; Phlebovirus, Bunyaviridae) is a mosquito–borne, zoonotic pathogen. In Senegal, RVFV was first isolated in 1974 from Aedes dalzieli (Theobald) and thereafter Ae. fowleri (de Charmoy), ochraceus Theobald, vexans (Meigen), Culex poicilipes (Theobald), Mansonia africana Ma. uniformis (Theobald). However, the vector competence of these local species has never been demonstrated making hypothetical transmission cycle proposed for West Africa based on serological data...
Yellow fever (YF) virus is a mosquito-borne belonging to the Flaviviridae family that circulates in tropical and subtropical areas of Africa South America. Despite availability an effective vaccine, YF remains threat travelers, residents endemic areas, unvaccinated populations. vaccination natural infection both induce production neutralizing antibodies. Serological diagnostic methods detecting virus-specific antibodies demonstrate high levels cross-reactivities with other flaviviruses. To...
In the progress towards malaria elimination, accurate diagnosis of low-density asymptomatic infections is critical. Low-density submicroscopic may act as silent reservoirs that maintain low-level residual transmission in community. Light microscopy, gold standard lacks sensitivity to detect parasitaemia. this study, presence and prevalence Plasmodium carriage were investigated estimate parasites reservoir among individuals living low areas Dielmo Ndiop, Senegal during dry season.A total...
Dramatic changes in transmission intensity can impact Plasmodium population diversity. Using samples from 2 distant time-points the Dielmo/Ndiop longitudinal cohorts Senegal, we applied a molecular barcode tool to detect parasite genotypes and complexity of infection that corresponded intensity. We observed striking statistically significant difference genetic diversity between populations. Furthermore, identified genotype Dielmo Ndiop previously Thiès, potentially implicating imported...
Dengue fever (DEN) is the most common arboviral disease in world and dengue virus (DENV) causes 390 million annual infections around world, of which 240 are inapparent 96 symptomatic. During past decade a changing epidemiological pattern has been observed Africa, with DEN outbreaks reported all regions. In Senegal, DENV serotypes have reported. These important changes profile occurring context where there no qualified vaccine against DEN. Further significant gap knowledge on vector bionomics...
Background When vaccines against the novel COVID-19 were available in Senegal, many questions raised. How long should non-pharmaceutical interventions (NPIs) be maintained during vaccination roll-out? What are best strategies? Methods In this study, we used an age-structured dynamic mathematical model. This model uses parameters based on SARS-CoV-2 virus, information different types of NPIs, epidemiological and demographic data, some relating to hospitalisations Senegal. Results all...
A nationwide cross-sectional epidemiological survey was conducted to capture the true extent of coronavirus disease 2019 (COVID-19) exposure in Senegal. Multi-stage random cluster sampling households performed between October and November 2020, at end first wave COVID-19 transmission. Anti-severe acute respiratory syndrome 2 (SARS-CoV-2) antibodies were screened using three distinct ELISA assays. Adjusted prevalence rates for design calculated each test separately, thereafter combined. Crude...
Historically low levels of seasonal influenza circulation were reported during the first years COVID-19 pandemic and mainly attributed to implementation nonpharmaceutical interventions. In tropical regions, influenza's seasonality differs largely, data on this topic are scarce. We analyzed from Senegal's sentinel syndromic surveillance network before after start assess changes in circulation. found that shows year-round Senegal has 2 distinct epidemic peaks: January-March rainy season...
The temporal distribution and spatial pattern of abundance mosquito vectors Rift Valley fever (RVf) West Nile (WNf) were studied during the 2005 2006 rainy seasons at Barkedji, Senegal. Mosquitoes collected every two weeks with CDC light traps dry ice 79 sites including temporary ponds, barren, shrubby savannah, wooded steppes, villages different distances (between 0 600 m) from nearest pond. distributions these varied between positively correlated rainfall for Aedes (Aedimorphus) vexans...
Abstract Background Influenza is a major cause of morbidity and mortality in Africa. However, lack epidemiological data remains for this pathology, the performances influenza-like illness (ILI) case definitions used sentinel surveillance have never been evaluated Senegal. This study aimed to i) assess performance three different ILI definitions, adopted by WHO, USA-CDC (CDC) European-CDC (ECDC) ii) identify clinical factors associated with positive diagnosis order develop an algorithm fitted...
Despite significant progress in malaria control over the past twenty years, remains a leading cause of child morbidity and mortality Tropical Africa. As most patients do not consult any health facility much uncertainty persists about true burden disease range individual differences susceptibility to malaria.
Dengue virus is becoming a major public health threat worldwide, principally in Africa. From 2016 to 2020, 23 outbreaks were reported Africa, West In Senegal, dengue have been yearly since 2017. Data about the circulating serotypes and their spatial temporal distribution limited that occurred between 2017 2018. Herein, we describe up-to-date molecular surveillance of DENV Senegal 2019 2023 around country. For this purpose, suspected DENV-positive samples collected subjected detection...
Given the growing threat posed by viral hemorrhagic fevers, development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well effective sustainable ensure downstream communication preparedness. A serological approach that offers high precision throughput, cost efficiency, multiplexing capacity critical. In this work, we evaluated a Luminex‐based multiplex microsphere immunoassay for five fever viruses (HFVs) among...
Rift Valley Fever and Crimean-Congo Hemorrhagic are two infections classified among the emerging diseases to be monitored with highest priority. Studies undertaken in human animals have shown endemicity of these arboviruses several African countries. However, most investigations were carried out on domestic cattle studies conducted populations either outdated or limited a small number well-known endemic areas. It is then critical better evaluate burden viruses Senegal at national scale.This...
Rift Valley fever is an emerging mosquito-borne disease that represents a threat to human and animal health. The exophilic exophagic behavior of the two main vector in West Africa (Aedes vexans Culex poicilipes), adverse events post-vaccination, lack treatment, render ineffective control. Therefore it essential develop information system facilitates decision-making implementation adaptation strategies. In East Africa, RVF outbreaks are linked with abnormally high rainfall, can be predicted...
The novel coronavirus disease 2019 (COVID-19) pandemic has spread from China to the rest of world. Africa seems less impacted with lower number cases and deaths than other continents. Senegal recorded its first case on March 2, 2020. We present here data collected 2 October 31, 2020 in Senegal.Socio-demographic, epidemiological, clinical virological information were suspected cases. To determine factors associated diagnosed infection, symptomatic death, multivariable binary logistic...
Abstract We characterized 01 autochthonous chikungunya virus (CHIKV) case from (The Gambia) through a newly implemented local arboviruses surveillance program in the, highlighting the first notification of Country. Identified is closely related to CHIKV West African genotype detected Kédougou (Senegal) 2023 and responsible large outbreak with up 300 confirmed cases. This work describes genomic proof subregional spread Africa.
Climatic and environmental variables were used successfully by using models to predict Rift Valley fever (RVF) virus outbreaks in East Africa. However, these are not replicable the West African context due a likely difference of dynamic emergence. For reasons specific mainly oriented risk mapping have been developed. Hence, areas high vector pressure or activity commonly predicted. factors impacting their occurrence poorly investigated still unknown. In this study, we examine impact climate...
Introduction Asymptomatic carriage of P. falciparum is frequent in areas endemic for malaria and individual diagnosis clinical attacks still difficult. We investigated the impact changes endemicity on diagnostic criteria an area seasonal transmission. Methods analyzed longitudinal data collected over 20 years from a daily survey all inhabitants Ndiop, rural community central Senegal, logistic regression model to investigate relationship between level Plasmodium parasitemia risk fever, with...
Knowing the burden of influenza is helpful for policy decisions. Here we estimated contribution influenza-like illness (ILI) visits associated with laboratory-confirmed among all clinic in a Senegal sentinel network. ILI data from ten sites were collected January 2013 to December 2015. was defined as an axillary measured fever more than 37.5 °C cough or sore throat. Collected nasopharyngeal swabs tested viruses by rRT-PCR. Influenza-associated influenza. For disease estimation, used all-case...
As of today, little data is available on COVID-19 in African countries, where the case management relied mainly a treatment by association between hydroxychloroquine (HCQ) and azithromycin (AZM). This study aimed to understand main clinical outcomes hospitalized patients Senegal from March October 20202. We described characteristics analysed status (alive discharged versus or died) at 15 days after Isolation Treatment Centres (ITC) admission among adult who received HCQ plus AZM those did...
The Oven drying kinetics mathematical modelling of four Senegalese onion varieties is carried out in the temperature range from 50 °C to 70 °C. R2 (dispersion test) and χ2 (fit between experimental data values predicted by models show that whatever variety, Verma et al. model one best fits oven kinetics. average for Galmi Violet, Safari, Gandiol F1 Orient are respectively 0.9848 0.9961 0.0010 0.006. This validated on solar greenhouse at variable temperatures during process. Drying...