Kai Liao

ORCID: 0009-0003-2673-255X
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Research Areas
  • Welding Techniques and Residual Stresses
  • Metal Forming Simulation Techniques
  • Advanced Surface Polishing Techniques
  • Advanced Welding Techniques Analysis
  • Fatigue and fracture mechanics
  • Non-Destructive Testing Techniques
  • Metallurgy and Material Forming
  • Laser and Thermal Forming Techniques
  • Lubricants and Their Additives
  • Tribology and Lubrication Engineering
  • Advanced Measurement and Metrology Techniques
  • Traditional Chinese Medicine Studies
  • Perovskite Materials and Applications
  • High-Velocity Impact and Material Behavior
  • Healthcare and Venom Research
  • High-Temperature Coating Behaviors
  • Acupuncture Treatment Research Studies
  • Vehicle emissions and performance
  • Head and Neck Cancer Studies
  • Erosion and Abrasive Machining
  • Optical Systems and Laser Technology
  • Surface Treatment and Residual Stress
  • Advanced Measurement and Detection Methods
  • Nanoplatforms for cancer theranostics
  • Cancer-related molecular mechanisms research

Guangzhou Medical University Cancer Hospital
2024-2025

Guangzhou Medical University
2021-2025

First Affiliated Hospital of Jinan University
2023-2024

Chengdu University
2024

Jiangxi University of Traditional Chinese Medicine
2024

Central South University
2008-2024

Central South University of Forestry and Technology
2013-2024

Changsha University of Science and Technology
2024

Institute of High Energy Physics
2023

University of Chinese Academy of Sciences
2023

Radiotherapy is the primary treatment for nasopharyngeal carcinoma (NPC); nonetheless, radioresistance remains leading cause of localized recurrence. Our study demonstrates a significant increase in N6-methyladenosine (m6A) methylase METTL3 NPC and other tumors. Mechanistically, acts as an m6A methylase, enhancing modification solute carrier family 7 member 11 (SLC7A11) transcript, which increases its stability expression, thereby inhibiting radiation-induced ferroptosis ultimately inducing...

10.7150/ijbs.100518 article EN cc-by-nc International Journal of Biological Sciences 2025-02-10

In the clinical practice, resistance of Candida albicans to antifungal agents has frequently emerged. Silver-nanoparticles (Ag-NPs) have been demonstrated property. We investigated potential for synergy between polyvinylpyrrolidone (PVP)-coated Ag-NPs and azole antifungal, such as fluconazole or voriconazole, against drug-resistant C. strain CA10. When agent was examined alone, voriconazole did not kill albicans, PVP-coated had only moderate killing ability. contrast, combinational treatment...

10.1166/jnn.2016.10934 article EN Journal of Nanoscience and Nanotechnology 2016-02-10

This study proposes a new strategy for achieving rapid volumetric heating of moldable low-dielectric-loss glass over wide temperature range using only microwave sources. As proof concept, both multi-physics modeling and experimental demonstration (MWH) Pyrex 7740 are performed. The results reveal that there is an activation threshold 400 °C this glass, i.e., below the mainly heated by SiC molds through interfacial heat transfer, while above it can be directly 2.45-GHz MWs dielectric loss....

10.1016/j.csite.2024.104364 article EN cc-by Case Studies in Thermal Engineering 2024-04-08

Abstract Polymerase 1 and transcript release factor (PTRF, encoding by Cavin-1 ) regulates interleukin 33 (IL-33) release, which is implicated in asthma development. Z-DNA binding protein (ZBP1)-sensing Z-RNAs induces necroptosis causes inflammatory diseases. House dust mite (HDM) the major source of allergen house strongly associated with development asthma. Whether PTRF via IL-33 ZBP1 mediates HDM-induced macrophage airway inflammation remains unclear. Here, we found that deficiency could...

10.1038/s41419-023-05971-1 article EN cc-by Cell Death and Disease 2023-07-15

Translocator protein 18 kDa (TSPO) positron emission tomography (PET) can be harnessed for the non-invasive detection of macrophage-driven inflammation. [18F]LW223, a newly reported TSPO PET tracer which was insensitive to rs6971 polymorphism, showed favorable performance characteristics in recent imaging study involving rat myocardial infarction model. To enable quantitative neuroimaging with we conducted kinetic analysis non-human primate (NHP) brain. Further, sought assess utility...

10.1016/j.phrs.2023.106681 article EN cc-by Pharmacological Research 2023-02-04

This study aimed to determine the optimal limiting dose reduce head and neck lymphedema in patients with early nasopharyngeal carcinoma (NPC) receiving intensity-modulated radiotherapy (IMRT) by setting rings at anterior posterior regions of neck. A total 15 NPC were included, 5 sets IMRT plans designed for each patient. Plan was a conventional plan without rings, while Plans B-E set gradients 20 Gy, 18 16 14 respectively, whose remaining parameters consistent A. Through Analysis Variance...

10.1038/s41598-025-96339-2 article EN cc-by-nc-nd Scientific Reports 2025-04-06

Practical challenges from both experiment and calculation sides were discussed for determining two piece twin land oil control ring friction. A floating liner engine was used study. Effects of system dynamics piston skirt friction addressed methods to mitigate them discussed. deterministic model calculation. Variation the surface roughness at different spots its effects on hydrodynamic boundary lubrication predictions multi-point correlation method introduced address variation model. Ring...

10.1177/1350650112465364 article EN Proceedings of the Institution of Mechanical Engineers Part J Journal of Engineering Tribology 2012-11-12

Aims: Preparation and evaluation of nanoparticles for tumor chemotherapy immunotherapy mild photothermal therapy oxaliplatin. Methods: The double emulsion method was used nanoparticle preparations. Polydopamine deposited on the surface, which further modified with folic acid. Cytotoxicity assays were carried out by cell counting kit-8. In vivo antitumor 4T1 tumor-bearing mice. Results: exhibited a 190 nm-diameter pomegranate-like sphere, could increase temperature to 43–46°C. distribution...

10.2217/nnm-2023-0335 article EN Nanomedicine 2024-03-04

Abstract Background Many methods have been proposed to increase cup coverage by host bone during primary total hip arthroplasty (THA) in osteoarthritis secondary developmental dysplasia of the (DDH). However, there was no study comparing results controlled fracture medial wall with a structural autograft bulk femoral head. Methods Sixty-seven hips classified as Crowe II/III were retrospectively included this cohort study, which consisted 33 fractures (group A) and 34 autografts B). The...

10.1186/s13018-020-02088-5 article EN cc-by Journal of Orthopaedic Surgery and Research 2020-11-26

10.1007/s11771-011-0692-8 article EN Journal of Central South University 2011-04-01

<div class="section abstract"><div class="htmlview paragraph">A twin-land oil control ring (TLOCR) model is used to evaluate TLOCR friction and the results are compared experiment measurement in a single cylinder floating liner engine under motoring condition. The based on correlation between hydrodynamic pressure film thickness, which generated using deterministic model. well-known three-regime lubrication predicted with for different tensions various running conditions. A good match found...

10.4271/2012-01-1321 article EN SAE technical papers on CD-ROM/SAE technical paper series 2012-04-13

In this study, thermal barrier coatings (TBC) consisting of 3.5 mol% Yb2O3-stabilized ZrO2 co-doped with 1 Gd2O3 and Yb2O3 (referred to as GdYb-YSZ) were fabricated by means air plasma spraying. The as-fabricated exhibited a metastable tetragonal (t′) structure. hot-corrosion behavior the GdYb–YSZ TBCs was investigated at 700, 800, 900, 1000 °C for 10 h in presence V2O5 molten salt. During corrosion tests, t′ phase transformed into monoclinic (m) phase; nevertheless, it still detected on...

10.3390/coatings13050886 article EN Coatings 2023-05-08

Carbon-based all-inorganic perovskite solar cells (C-PSCs) are promising alternatives compared with conventional organic–inorganic halide PSCs because of their good thermal stability. However, low carrier transport efficiency and energy level mismatch the upper interface device limit further improvement power conversion (PCE), perovskites extremely sensitive to oxygen humidity, which seriously damages long-term stability device. Upper modification is an effective solution improve PCE...

10.1021/acsami.4c17934 article EN ACS Applied Materials & Interfaces 2024-12-11

Background: Oil well cement retarder is an additive that can extend time for thickening slurry, which ensure the safety of cement. At present, oil mainly composed synthetic materials, are divided into three major categories: compound polymer, AMPS polymer and non-AMPS. Methods: In this paper, research status in recent years reviewed, its shortcomings development trends analyzed. It pointed out shortage lies problems, including large temperature sensitivity, small application range, abnormal...

10.2174/1872212114999200710144827 article EN Recent Patents on Engineering 2020-07-16

With large-scale electric vehicles (EVs) connected to the distribution network, charging demand of EVs aggravates peak-to-valley difference, which brings massive pressure power system. How environmentally optimize system considering features EVs' has become a mainstream issue. To tackle this challenge, low carbon economic dispatch model for integrated energy is proposed under an electric-traffic environment based on user equilibrium (UE) theory. This considers emission and multiple...

10.1016/j.egyr.2022.07.008 article EN cc-by-nc-nd Energy Reports 2022-07-14

Low/high temperature stress is one of the key abiotic factors restricting implementation microalgal large-scale production. Metabolism, involved in resistances, have been reported plants, but related research microalgae far behind. This study analyzed transcriptional changes Nannochloropsis oceanica under low and high stresses by RNA-seq technology. Results indicated that total differentially expressed gene (DEG) amount was much more than stress. GO enrichment analysis suggested DEGs were...

10.1016/j.aqrep.2022.101365 article EN cc-by-nc-nd Aquaculture Reports 2022-10-14

Purpose: To study the effect of overexpression Rac1 on radiosensitivity transplanted nasopharyngeal carcinoma (NPC) in nude mice, and mechanism involved. &#x0D; Methods: Forty Lucky SPF-grade male thymus-free mice were used. Mice divided into 4 groups: control, Rac1, inhibition, inhibition control groups, each with 10 mice. The prepared cell lines treated 6 MV x-ray. Before after radiation, growth tumors group was monitored. Histomorphological images obtained using hematoxylin eosin...

10.4314/tjpr.v22i4.11 article EN cc-by Tropical Journal of Pharmaceutical Research 2023-05-11
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