- Corrosion Behavior and Inhibition
- Advanced Polymer Synthesis and Characterization
- Block Copolymer Self-Assembly
- Lignin and Wood Chemistry
- Pickering emulsions and particle stabilization
- Metal-Organic Frameworks: Synthesis and Applications
- Polymer Surface Interaction Studies
- ZnO doping and properties
- Ferroptosis and cancer prognosis
- Ionic liquids properties and applications
- Mesoporous Materials and Catalysis
- Chemical Synthesis and Reactions
- Genomics, phytochemicals, and oxidative stress
- Covalent Organic Framework Applications
- Concrete Corrosion and Durability
- Enzyme-mediated dye degradation
- Advanced Cellulose Research Studies
- Catalytic Processes in Materials Science
- Autophagy in Disease and Therapy
- Luminescence and Fluorescent Materials
- Metal and Thin Film Mechanics
- Surfactants and Colloidal Systems
- Polymer composites and self-healing
- Anodic Oxide Films and Nanostructures
- Sirtuins and Resveratrol in Medicine
China University of Petroleum, East China
2013-2025
Zhejiang University
2023-2024
South China University of Technology
2013-2024
Anhui University of Science and Technology
2024
Shaoxing People's Hospital
2023
Qingdao Center of Resource Chemistry and New Materials
2017-2018
Doxorubicin (DOX) is a commonly used chemotherapy drug widely applied in various cancers such as breast cancer, leukemia, and sarcomas. However, its usage limited by cardiotoxicity. Additionally, the cardiac toxicity of DOX accumulates with dose duration, making it imperative to identify therapeutic targets for DOX-induced cardiomyopathy (DIC). It has been reported that miRNAs are involved progression DIC. Mir-34a-5p identified an early diagnostic marker While studies have shown involvement...
This study demonstrated for the first time that paeoniflorin (PA) exerts protective effects in diabetic cardiomyopathy mice by alleviating myocardial damage, resisting ferroptosis, and changing community composition structure of intestinal microbiota, 11,12-epoxyeicosatrienoic acid (11,12-EET) may serve as a key contributor its therapeutic efficacy.
Three chitosan ionic liquid type Schiff bases (CS-IL-SBs) were synthesized by grafting three aldehydes (vanillin, cinnamaldehyde, and pyridine-4-carboxaldehyde) on CS-IL (chitosan grafted with p -toluene sulfonic acid) through a base reaction.
This study demonstrated for the first time protective effect of emodin against DIC and verified by FMT that its cardioprotective was achieved remodeling gut microbiota composition, resulting in attenuation ferroptosis. Furthermore, we these effects were mediated redox-related gene Nrf2.
Diabetic heart damage can lead to cardiomyocyte death, which endangers human health. Baicalin (BAI) is a bioactive compound that plays an important role in cardiovascular diseases. Sentrin/SUMO-specific protease 1 (
A new multi-shelled hollow mesoporous organosilica (M-HPMO) bearing thiol moieties on dual surfaces of the pore has been prepared.
Using dissipative particle dynamics simulation, we probe the tunable permeability of cross-linked microcapsules made from pH-sensitive diblock copolymers poly(ethylene oxide)-b-poly(N,N-diethylamino-2-ethyl methacrylate) (PEO-b-PDEAEMA). We first examine self-assembly non-cross-linked and their pH-responsive collapse then explore effects cross-linking block interaction on swelling or deswelling microcapsules. Our results reveal a preferential loading hydrophobic dicyclopentadiene (DCPD)...
We demonstrated first that the nuclear factor erythroid 2-related 2 (Nrf2) activator RTA 408 has a protective effect against diabetic cardiomyopathy. found could stimulate entry of Nrf2 protein, regulate mitochondrial fission-fusion balance, and redistribute p65, which significantly alleviated oxidative stress level in cardiomyocytes, thereby reducing apoptosis inflammation, protecting systolic diastolic functions heart.
Carbon dots as eco-friendly corrosion inhibitors still face challenges due to their propensity agglomerate and undefined structure-activity relationship in corrosive environment. Here, we intend address these by fusing ionic liquids (IL) with N-doped carbon (i.e., IL-NCD) which effectively solves the agglomeration issue strong acidic solution, exhibiting superior water-solubility. Weight loss electrochemical evaluations indicate IL-NCD's (at 60 mg/L) remarkable inhibition efficiency 97.34%...
<title>Abstract</title> Dibenzyltoluene (DBT) is one of the most promising hydrogen storage media liquid organic carriers (LOHCs), but it difficult to solve problems low catalyst selectivity and deactivation caused by high by-products dehydrogenation. This study designed Pt<sub>2.0</sub>Cu<sub>0.1</sub>/Al<sub>2</sub>O<sub>3</sub>-900 ℃ that could balance activity, stability dehydrogenation perhydrodibenzyltoluene (18H-DBT). method involved appropriate acid pretreatment Pt-Cu synergistic...
Multigeometry nanoparticles with high complexity in composition and structure have attracted significant attention for enhanced functionality. We assess a simple but versatile strategy to construct hybrid subdivided geometries through the cooperative assembly of diblock copolymer blends asymmetric architectures. report formation multicompartmental, vesicular, cylindrical, spherical structures from pure AB systems. Then, we explore assemblies binary AB/AC blends, where two incompatible,...
Dissipative particle dynamics (DPD) simulation is used to study the effect of pH on morphological transition in micelles assembled from dirhamnolipids (diRLs), and analyze pH-driven mechanism influence factors micellar surface patterns. At < 4.0, various multilayer structures with homogeneous patterns are observed, whereas diRLs can self-assemble into novel anisotropic morphologies phase-separated at > 7.4, such as patchy spherical micelles, rod-like helical a lamellar phase The change...
Multicompartment nanostructures, such as microcapsules with clearly separated shell and core, are not easily accessible by conventional block copolymer self-assembly.
Controlling the self-assembly and polymorphic transition of surfactants is a challenging but meaningful topic for chemists materials scientists, which significant preparation advanced nanomaterials. We presented coarse-grained (CG) molecular dynamics (MD) simulations on confined within carbon nanotube (CNT) arrays. Under effect confinement, an intriguing "rod-double helix-hexagon-worm" was observed with varying size confining space. The also showed that confinement CNT arrays does not break...
In this study, the degradation performance of Fe–Nb–Cu–Si–B amorphous alloy powders towards methyl orange in an ultrasonic Fenton-like process is reported. EPR experiments proved that ˙OH and ˙O 2 − were main reactive radicals.
Observational studies indicate that serum sex hormone-binding globulin (SHBG) levels are inversely correlated with blood lipid and coronary heart disease (CHD) risk. Given dyslipidemia is an established risk factor for CHD, we aim to employ Mendelian randomization (MR) in conjunction mediation analysis confirm the mediating role of association between SHBG CHD. First, assessed causality five cardiovascular diseases using univariable MR. The results revealed reduced myocardial infarction, as...
In order to explore the potential application of green solvent ionic liquids (ILs) in kraft pulping process, eucalyptus wood was pretreated by [Mmim]DMP before normal pulping. The results showed that materials shortly liquid had a higher yield and viscosity coupled with lower potassium permanganate value residual lignin content pulp, as result cooking process. It also inferred alkaline pretreatment could dissolve effectively from fiber stronger binding force more entangled properties. Paper...