Megan Mrubata

ORCID: 0009-0003-4919-7756
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About
Contact & Profiles
Research Areas
  • HIV/AIDS Research and Interventions
  • Mobile Health and mHealth Applications
  • ICT in Developing Communities
  • HIV-related health complications and treatments
  • HIV/AIDS drug development and treatment
  • Global Maternal and Child Health
  • Cervical Cancer and HPV Research
  • Reproductive tract infections research
  • Adolescent Sexual and Reproductive Health
  • Hepatitis B Virus Studies
  • Focus Groups and Qualitative Methods

University of Cape Town
2014-2024

Desmond Tutu HIV Foundation
2014

BackgroundLate initiation of antiretrovirals in pregnancy is associated with increased risk perinatal transmission and higher infant mortality. We report the final 72-week postpartum results for efficacy safety dolutegravir-based compared efavirenz-based regimens mothers infants.MethodsDolPHIN-2 was a randomised, open-label trial. Pregnant women South Africa Uganda aged at least 18 years, untreated but confirmed HIV infection an estimated gestation 28 weeks, initiating antiretroviral therapy...

10.1016/s2352-3018(22)00173-4 article EN cc-by The Lancet HIV 2022-07-26

Mobile health interventions are common in public settings Africa, and our preliminary work showed that smartphones increasing South Africa. We developed a novel smartphone app-CareConekta-that used GPS location data to characterize personal mobility improve engagement HIV care among pregnant postpartum women living with The app also the user's map nearby clinics.

10.2196/44945 article EN cc-by JMIR mhealth and uhealth 2023-04-21

Background. HIV-infected adolescents may be at higher risk for high-grade cervical lesions than HIV-uninfected adolescents. The purpose of this study was to compare the prevalence high-risk HPV (HR-HPV) infections and Pap smear abnormalities between these two groups. Methods. In cross-sectional study, we compared DNA results 35 50 in order determine HR-HPV genotypes cytological abnormalities. Comparisons were made using Pearson<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1155/2014/498048 article EN cc-by Infectious Diseases in Obstetrics and Gynecology 2014-01-01

Purpose Pregnant and postpartum women living with HIV in South Africa are at high risk of dropping out care, particularly after delivery. Population mobility may contribute to disruptions known be especially mobile. To improve engagement care during the peripartum period, we developed CareConekta, a smartphone application (app) that uses GPS coordinates characterise allow for real-time intervention. We conducted randomised controlled pilot study assess feasibility, acceptability initial...

10.1136/bmjopen-2022-064946 article EN cc-by-nc BMJ Open 2022-11-01

Mobile health (mHealth) initiatives are increasingly common in low-resource settings, but the appropriateness of smartphone interventions care settings is uncertain. More research needed to establish and feasibility integrating new mHealth modalities (novel apps social media apps) South African context.In this study, inform future interventions, we describe ownership, preferences, usage patterns among pregnant women living with HIV Gugulethu, Africa.We screened from December 2019 February...

10.2196/43855 article EN cc-by JMIR Formative Research 2023-04-24

This prospective cohort study investigated the mobility patterns of 200 pregnant and postpartum women living with HIV in South Africa. Participants were enrolled during their third trimester from routine antenatal care near Cape Town, Africa, followed for six months postpartum. Quantitative data collected at enrollment follow-up. Mobility (self-reported) was common among participants, despite brief period concurrent COVID-19 pandemic. While most reported stability current residence, 71% had...

10.1080/09540121.2023.2299745 article EN AIDS Care 2024-01-04

<sec> <title>BACKGROUND</title> Mobile health (mHealth) initiatives are increasingly common in low-resource settings, but the appropriateness of smartphone interventions care settings is uncertain. More research needed to establish and feasibility integrating new mHealth modalities (novel apps social media apps) South African context. </sec> <title>OBJECTIVE</title> In this study, inform future interventions, we describe ownership, preferences, usage patterns among pregnant women living with...

10.2196/preprints.43855 preprint EN 2022-10-27

Abstract Background Mobile health (mHealth) initiatives are increasingly common in low-resource settings, but the appropriateness of smartphone interventions is uncertain. To inform future mHealth interventions, we describe ownership, preferences and usage patterns among women living with HIV (WLHIV) Gugulethu, South Africa. Methods We screened pregnant WLHIV from December 2019 - February 2021 for CareConekta trial. sociodemographic characteristics mobile phone ownership all (n=639), use...

10.1101/2022.09.29.22280417 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-09-30

<sec> <title>BACKGROUND</title> Mobile health interventions are common in public settings Africa, and our preliminary work showed that smartphones increasing South Africa. We developed a novel smartphone app—CareConekta—that used GPS location data to characterize personal mobility improve engagement HIV care among pregnant postpartum women living with The app also the user’s map nearby clinics. </sec> <title>OBJECTIVE</title> aimed describe feasibility, acceptability, initial efficacy of...

10.2196/preprints.44945 preprint EN 2022-12-09
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