Yimin Zhao

ORCID: 0009-0003-5474-702X
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About
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Research Areas
  • Inflammasome and immune disorders
  • Gout, Hyperuricemia, Uric Acid
  • Heme Oxygenase-1 and Carbon Monoxide

Air Force Medical University
2023

Type 2 diabetes mellitus (T2DM) exacerbates irreversible bone loss in periodontitis, but the mechanism of impaired regeneration caused by abnormal metabolic process T2DM remains unclear. Exosomes are regarded as critical mediator diabetic impairment via organ or tissue communication. Here, we find that abnormally elevated exosomes derived from metabolically liver significantly enriched periodontal region and induced pyroptosis ligament cells (PDLCs). Mechanistically, fatty acid synthase...

10.1016/j.bioactmat.2023.10.022 article EN cc-by-nc-nd Bioactive Materials 2023-11-09
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