A5103052922- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Toxoplasma gondii Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Congenital Anomalies and Fetal Surgery
- IL-33, ST2, and ILC Pathways
Ningxia Medical University
2023-2025
Huazhong University of Science and Technology
2017
Tongji Hospital
2017
Introduction Eg.P29 is a specific protein of E.granulosus metacestod, and has been able to induce high levels protection in mice sheep against challenge with protoscolex . Therefore, plays crucial role the growth development E. granulosus metacestode. However, function remains unknown. During process life, commonly other proteins form complex network interactions play function. In this study, we identified interacting molecules for foundation exploring Methods Some basic information about...
Adiponectin is a multifunctional adipokine that has several oligomeric forms in the blood stream, which broadly regulates innate and acquired immunity. Therefore, this study, we aimed to observe differentiation of T helper (Th) cells expression costimulatory signaling molecules affected by adiponectin. The mRNA protein levels adiponectin its receptors oxidized low density lipoprotein cholesterol-treated endothelial were assayed real time PCR immunofluorescence. then treated with or without...
Introduction The Notch signaling pathway is involved in the development of many diseases; it regulates dendritic cells (DCs), and affects immune response DC-mediated T cells. We previously found that ferritin malate dehydrogenase (mMDH) Echinococcus granulosus (E.granulosus) induced different responses through sensitized DCs. Therefore, study we explored whether differentiation DCs, causing changes DCs with E. antigens, clarified E.granulosus infection. Methods used inhibitor...
Different subtypes of dendritic cells (DCs) can induce different types immune responses. Our previous study found that Echinococcus granulosus (E. granulosus) antigens (Eg.ferritin, Eg.mMDH and Eg.10) stimulated DC differentiation to produced responses.To further understand whether Eg.ferritin, Eg.10 affect the DC-mediated response by promoting monocytes DCs.Bone marrow-derived were exposed three E. on days 0, 3, 5, 7. The percentage monocyte-derived DCs (moDCs), subsets, expression surface...