A5055811997- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Synthesis and Characterization of Heterocyclic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Synthesis and biological activity
- Extracellular vesicles in disease
- Magnetism in coordination complexes
- Electron Spin Resonance Studies
- MicroRNA in disease regulation
- Organometallic Compounds Synthesis and Characterization
- Synthesis and Biological Evaluation
- Ferroptosis and cancer prognosis
- Energetic Materials and Combustion
- Thermal and Kinetic Analysis
Bengbu Medical College
2022-2024
Qufu Normal University
2024
Ferroptosis is a new form of cell death that relies on iron and involves an imbalance intracellular reactive oxygen species (ROS), which expected to help alleviate bottlenecks in tumor treatment. Herein, sorafenib‐loaded folic acid‐armored iron‐based nMOF was designed for synergistic inducing ferroptosis tumors. The particle size the synthesized SM@F about 210nm, drug loading rate 24.74%. can be degraded releases sorafenib ions slowly, resulting release overload after being highly uptaken by...
Three metal complexes [CuL(NO3)]n (1), [Cd(HL)(NO3)2]n (2) and [EuL(HCOOH)(H2O)(NO3)2] (3) were synthesized with a pyridyl Schiff ligand L (N'-[(1E)-pyridin-2-ylmethylidene]pyridine-4-carbohydrazide). A crystallographic study revealed that 1 2 have chain structure, complex 3 is zero-dimensional monomer. In vitro cytotoxicity studies showed had the best antiproliferative activity against SMMC-7721 cells MDA-MB-231 single-digit IC50 values, both exceeding those of control drug cisplatin by...
1 shows low sensitivity and high stability with an intense exothermic process at 295.1 °C 3 is a lanthanide-based energetic metal–organic framework.
Three metal complexes [CuL(NO 3 )] n (1) , [Cd(HL)(NO ) 2 ] (2) and [EuL(HCOOH)(H O)(NO (3) were synthesized with a pyridyl Schiff ligand L (N'-[(1E)-pyridin-2-ylmethylidene]pyridine-4-carbohydrazide). Crystallographic study reveals 1 have chain structure, complex is zero-dimensional monomer. In vitro cytotoxicity studies showed that had the best antiproliferative activity against SMMC-7721 cells MDA-MB-231 single-digit IC 50 values, both exceeding those of control drug cisplatin by far. The...