A5090733558- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Mesoporous Materials and Catalysis
- Zeolite Catalysis and Synthesis
- Metal complexes synthesis and properties
- Synthesis and Characterization of Heterocyclic Compounds
- Bioactive Natural Diterpenoids Research
- Enhanced Oil Recovery Techniques
- Catalytic Processes in Materials Science
- MicroRNA in disease regulation
- Cell death mechanisms and regulation
- Polyoxometalates: Synthesis and Applications
- Extracellular vesicles in disease
- Organometallic Compounds Synthesis and Characterization
- Ferroptosis and cancer prognosis
- Magnetism in coordination complexes
Bengbu Medical College
2022-2024
Zeolites are microporous silicates with a large variety of applications as catalysts, adsorbents, and cation exchangers. Stable silica-based zeolites increased porosity in demand to allow adsorption processing molecules but challenge our synthetic ability. We report new, highly stable pure silica zeolite called ZEO-3, which has multidimensional, interconnected system extra-large pores open through windows made by 16 14 silicate tetrahedra, the least dense polymorph known so far. This was...
Oridonin (Ori) is a naturally existing diterpenoid substance that mainly exists in the Chinese medicinal plant Rabdosia rubescens. It was previously found to possess intriguing biological properties; however, quick clearance from plasma and limited solubility water restricts its use as drug. Several metal–organic frameworks (MOFs), having big surfaces large pores, have recently been considered promising drug transporters. The zeolitic imidazolate framework-8 (ZIF-8), form of MOF consisting...
Ferroptosis is a new form of cell death that relies on iron and involves an imbalance intracellular reactive oxygen species (ROS), which expected to help alleviate bottlenecks in tumor treatment. Herein, sorafenib‐loaded folic acid‐armored iron‐based nMOF was designed for synergistic inducing ferroptosis tumors. The particle size the synthesized SM@F about 210nm, drug loading rate 24.74%. can be degraded releases sorafenib ions slowly, resulting release overload after being highly uptaken by...
Three metal complexes [CuL(NO3)]n (1), [Cd(HL)(NO3)2]n (2) and [EuL(HCOOH)(H2O)(NO3)2] (3) were synthesized with a pyridyl Schiff ligand L (N'-[(1E)-pyridin-2-ylmethylidene]pyridine-4-carbohydrazide). A crystallographic study revealed that 1 2 have chain structure, complex 3 is zero-dimensional monomer. In vitro cytotoxicity studies showed had the best antiproliferative activity against SMMC-7721 cells MDA-MB-231 single-digit IC50 values, both exceeding those of control drug cisplatin by...
Three metal complexes [CuL(NO 3 )] n (1) , [Cd(HL)(NO ) 2 ] (2) and [EuL(HCOOH)(H O)(NO (3) were synthesized with a pyridyl Schiff ligand L (N'-[(1E)-pyridin-2-ylmethylidene]pyridine-4-carbohydrazide). Crystallographic study reveals 1 have chain structure, complex is zero-dimensional monomer. In vitro cytotoxicity studies showed that had the best antiproliferative activity against SMMC-7721 cells MDA-MB-231 single-digit IC 50 values, both exceeding those of control drug cisplatin by far. The...
Zeolites are microporous silicates that find an ample variety of applications as catalysts, adsorbents, and cation exchangers. Stable silica-based zeolites with increased porosity in demand to allow adsorption processing large molecules, but challenge our synthetic ability. Here we report a novel, highly stable pure silica zeolite, ZEO-3, multidimensional, interconnected system extra-large pores open through windows made by 16 14 SiO4 tetrahedra, which is the less dense polymorph known so...
Oridonin (Ori) is a natural active component with superior anticancer properties; however, its clinical application severely limited by the inherent properties of short half‐life, bioavailability, and low water solubility. Some metal–organic frameworks (MOFs) materials have unique porous structure appropriate nanometer particle size that are attractive in drug delivery. Herein, folic acid (FA)‐functionalized Fe‐MOF was designed to efficiently incorporate Ori for targeting delivery cancer...
Zeolites are microporous silicates that find an ample variety of applications as catalysts, adsorbents, and cation exchangers. Natural synthetic zeolites possess a fully connected three-dimensional network corner-sharing SiO4 tetrahedra (i.e. they tectosilicates or framework silicates, with Si occasionally substituted by other atoms). Stable silica-based increased porosity interest to allow processing large molecules, but challenge our ability. Here we report novel zeolite, ZEO-3,...
Stable silica-based zeolites with increased porosity are in demand to allow adsorption and processing of large molecules, but challenge our synthetic ability. Here we report a novel, highly stable pure silica zeolite, ZEO-3, multidimensional, interconnected system extra-large pores open through windows made by 16 14 SiO4 tetrahedra, which is the less dense polymorph known so far. This zeolite formed an unprecedented 1D-to-3D topotactic condensation approach from chain silicate. With specific...