- Endometrial and Cervical Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- RNA Interference and Gene Delivery
- Indoor and Outdoor Localization Technologies
- AI in cancer detection
- Radio Wave Propagation Studies
- Smart Parking Systems Research
- Intraocular Surgery and Lenses
- Viral gastroenteritis research and epidemiology
- Mycobacterium research and diagnosis
- Immunotherapy and Immune Responses
- Viral Infections and Immunology Research
- Diagnosis and treatment of tuberculosis
- Retinal Imaging and Analysis
- Animal Virus Infections Studies
- Retinal and Macular Surgery
- Animal Disease Management and Epidemiology
- Tuberculosis Research and Epidemiology
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Shanghai Library
2023
Shanghai Jiao Tong University
2023
First Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
The First People’s Hospital of Lianyungang
2018
Capital Medical University
2017
Beijing Chest Hospital
2017
Human papillomavirus (HPV) infections account for several human cancers. There is an urgent need to develop therapeutic vaccines targeting preexisting high-risk HPV (such as 16 and 18) lesions, which are insensitive preventative vaccines. In this study, we developed a lipid nanoparticle–formulated mRNA-based vaccine (mHTV), mHTV-02, the E6/E7 of HPV16 HPV-18. mHTV-02 dramatically induced antigen-specific cellular immune response robust memory T-cell immunity in mice, besides significant CD8...
Gynecological malignancies, particularly lymph node metastasis, have presented a diagnostic challenge, even with traditional imaging techniques such as CT, MRI, and PET/CT. This study was conceived to explore and, subsequently, bridge this gap through more holistic innovative approach. By developing comprehensive framework that integrates both non-image data detailed MRI image analyses, harnessed the capabilities of multimodal federated-learning model. Employing composite neural network...
Enterovirus-A71 (EV-A71) is the second most common causative agent after coxsackievirus A16 of hand, foot, and mouth disease. The capsids EV-A71 consist 60 copies each four viral structural proteins (VP1-VP4). VP1 highly exposed surface accessible, playing a central role in virus particle assembly, attachment, entry. To gain insight into conserved residues at positions 75, 78, 88 capsid protein these processes, an alanine-scanning analysis was performed using infectious cDNA clone EV-A71....
This study aimed to evaluate the diagnostic efficacy of CT, MRI, and PET/CT in detecting lymph node metastasis (LNM) patients with gynecologic malignancies. A total 567 diagnosed cervical carcinoma (CC) endometrial (EC) were included this study. The results indicated that demonstrated higher levels sensitivity but lower specificity compared CT MRI. Additionally, a deep learning-based multimodal federated learning model was implemented, which integrated non-image MRI data, improve accuracy...
This paper presents the experience in implementation and application of a large-scale Indoor Location-Based Service (LBS) an academic library. We deployed indoor positioning system within school library that leverages 550 Bluetooth beacons, covering area approximately 12,000 square meters. allows users to engage with location-aware book navigation services via web interface on their mobile devices. Upon locating interest, enters mode, updating guiding based current location Utilizing users’...
This study examined the effects of respiratory targeted care on pulmonary rehabilitation and nutritional status in elderly patients with chronic obstructive disease complicated failure. From February 2018 to May 2023, 72 failure were randomized into an experimental group (n = 36) for a control routine care. The non-invasive ventilation time, duration critical illness, total time shorter than (P < 0.05). Besides, showed better quality sleep, Activities Daily Living scores, nursing...