A5108672295- Ear Surgery and Otitis Media
- Antibiotic Use and Resistance
- Hearing Loss and Rehabilitation
- Viral gastroenteritis research and epidemiology
- Clostridium difficile and Clostridium perfringens research
- Nosocomial Infections in ICU
- Hearing, Cochlea, Tinnitus, Genetics
- Respiratory and Cough-Related Research
- Antibiotic Resistance in Bacteria
- Obstructive Sleep Apnea Research
- Noise Effects and Management
- Essential Oils and Antimicrobial Activity
- Microscopic Colitis
- Bacillus and Francisella bacterial research
- Phytochemicals and Antioxidant Activities
- Blood Coagulation and Thrombosis Mechanisms
- Management of metastatic bone disease
- Venous Thromboembolism Diagnosis and Management
- Streptococcal Infections and Treatments
- Asthma and respiratory diseases
- Delphi Technique in Research
- Fungal Plant Pathogen Control
- Phonocardiography and Auscultation Techniques
- Meningioma and schwannoma management
- Cardiovascular Disease and Adiposity
Grigore T. Popa University of Medicine and Pharmacy
2017-2024
Clinical Emergency Hospital Bucharest
2024
Institutul National de Sanatate Publica
2010-2011
Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed estimate the burden of infections caused by public concern in countries EU European Economic Area (EEA) 2015, measured number cases, deaths, disability-adjusted life-years (DALYs).We estimated incidence with 16 antibiotic resistance-bacterium combinations from Antimicrobial Resistance Surveillance Network...
Background Antimicrobial resistance has become a serious threat to public health undermining the efficacy of existing antimicrobials (including last-resort ones) while very few novel antimicrobial agents are in development pipeline. The interventions aimed contain need continuous surveillance new mechanisms emergence and spread ones. Romania participated since 2002 as member European Resistance Surveillance Network (EARS) for invasive infection; it is network which collects data most...
Aims:To investigate the epidemiology of Clostridium difficile infection in Romanian hospitals.Methods: A survey was conducted at nine hospitals throughout Romania between November 2013 and February 2014. Results:The identified 393 patients with infection.The median age 67 years (range: 2-94 years); 56% were aged >65 years.The mean prevalence 5.2 cases per 10.000 patient-days.The highest prevalences 24.9 20 patient-days specializing gastroenterology infectious diseases,...
The perceived impact of hearing loss varies considerably among those affected due to the heterogeneous types loss, their diverse etiologies, and different rehabilitation possibilities. Therefore, assessing listening skills in a daily context using questionnaires is essential. This study aimed investigate validity reliability adapted version Speech, Spatial Qualities Hearing Scale 12 (SSQ12) Romanian language. SSQ12 12-item self-reporting questionnaire that assesses range everyday situations....
Background The use of antimicrobials is the main cause for development antimicrobial resistance. Many countries increasingly implement actions to control resistance through rational use. information on national and local consumption can be an important source planning interventions monitoring progress towards a more prudent antibiotics. In Romania, particularities were never analyzed before 2012. We aimed identify specific features in calculate quality indicators community antibiotic usage.
Inflammatory mediators play an important role in the pathogenesis of otitis media by initiating and maintaining inflammatory response to infection. The presence may be one reasons, some patients, for acute transforming into chronic media. present study included 60 patients admitted Clinical Rehabilitation Hospital, Iasi, Romania, surgery. control group comprised 30 healthy individuals. Serum levels interleukin 1α (IL‑1α), 6 (IL‑6) 8 (IL‑8) were measured prior surgery compared among with...
Methods We collected data for all 398 confirmed or probable cases of CDI admitted during 15 November 2013-28 February 2014 in 11 hospitals: 5 from Bucharest, and 7 Cluj, Iasi, Timisoara, Târgu Mures Brasov. PCR ribotyping was performed at Cantacuzino Institute E-test (for moxifloxacin metronidazole) binary toxin gene identification (PCR) were Matei Bals Institute. The hospitals sent a maximum 20 feces samples each test.
Background/Objectives: Understanding speech in background noise is a challenging task for listeners with normal hearing and even more so individuals impairments. The primary objective of this study was to develop Romanian material assess perception diverse auditory populations, including those various types loss. goal create versatile tool that can be used different configurations expanded future studies examining performance across populations rehabilitation methods. Methods: This outlines...
Chronic tympanic membrane perforation represents a prevalent otological condition, necessitating reliable animal model for the validation and safety assessment of surgical techniques materials employed in myringoplasty. This prospective study involved establishment chronic models 16 chinchillas. A thermic myringotomy was conducted on right ear (study group), followed by cold instrument myringotomy, coupled with topical application mitomycin C dexamethasone solution left (control group)....
Oxidative stress plays an important role in multiple diseases by disturbing the oxidant-antioxidant balance.The aim of this study was to evaluate antioxidative status patients with chronic suppurative otitis media (CSOM).We conducted a prospective that included 60 diagnosed and without cholesteatoma.The catalase (CAT) superoxide dismutase (SOD) activities were determined erythrocytes respectively serum patients.We noticed antioxidant enzyme SOD activity CSOM cholesteatoma had statistically...
Quality of life is a widely used concept that tends to become an important part clinical management. The present study performs analysis the impact suppurative chronic otitis media with and without cholesteatoma on quality life, using COMQ-12 questionnaire. It was applied group 40 healthy people patients before surgery, answers questions were analyzed correlated socioeconomic factors. After confirmation diagnosis based imaging information, completed observed ear problems had negative impacts...
Abstract This study investigated the antibiotic susceptibility patterns and genetic resistance markers of 35 C. difficile strains isolated from patients with infection. Vancomycin, metronidazole, tigecycline, teicoplanin, rifampicin, moxifloxacin, cefotaxime, tetracycline, erythromycin, clindamycin, chloramphenicol, linezolid imipenem MICs were determined for toxigenic belonging to PCR ribotypes (PR) 012 (2), 014 (4), 017 (3), 018 027 (17), 046 087 (3) 115 (2). Results showed vancomycin,...
Abstract A prolonged outbreak of Healthcare-Associated Infections (HCAIs) evolved since December 2013, in a Newborns Unit from Hospital A, sited the North-Eastern development region, Romania. first cluster consisted 19 cases, which 18 infections newborns and 1 labour infectious complication mother. Except for five cases declared treated Neonatology as hospital-acquired infections, other were discharged further required rehospitalisation treatment. Eight these innitialy readmitted to...
The oxidative stress is linked to many chronic diseases.The aim of the study was assess in suppurative otitis media. prospective included a group 60 patients with different forms media (CSOM), cholesteatoma recidivism and control 30 healthy people. total antioxidant capacity (TAC) malondialdehyde (MDA) concentrations were determined serum thepatients. We noticed significant lower mean TAC levels (p[ 0.001) (CSOM) without compared group. MDA had significantly higher values group.The imbalance...
first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Size: Aa Line Spacing: Column Width: Background: Open AccessExtended Abstract Formulation and Evaluation of an Antimicrobial Cream Containing Cinnamon Oil for Topical Application † by Fawzia Sha'at 1,2,*, Ramona-Daniela Pavaloiu 1,2, Cristina Hlevca 1, Adela Staras Iuksel Rasit Erand Mati 3, Mihaela Voicu Roxana Serban 3 Lucia Pirvu 1 National Institute Chemical-Pharmaceutical Research & Development—ICCF,...