A5007071340- COVID-19 and healthcare impacts
- Epigenetics and DNA Methylation
- COVID-19 epidemiological studies
- Antibiotic Use and Resistance
- Cervical Cancer and HPV Research
- Antibiotic Resistance in Bacteria
- Climate Change and Health Impacts
- COVID-19 Clinical Research Studies
- Global Health Care Issues
- Parasitic Infections and Diagnostics
- Global Cancer Incidence and Screening
- Urinary Tract Infections Management
- Pneumonia and Respiratory Infections
- Colorectal Cancer Screening and Detection
- COVID-19 Pandemic Impacts
- Birth, Development, and Health
- Cancer Risks and Factors
- COVID-19 and Mental Health
- Nutritional Studies and Diet
- Amoebic Infections and Treatments
- Folate and B Vitamins Research
- Tuberculosis Research and Epidemiology
- Gestational Diabetes Research and Management
- Influenza Virus Research Studies
- Parasites and Host Interactions
University of Nicosia
2020-2025
University of Cyprus
2024
University of Catania
2011-2019
Health Protection Surveillance Centre
2019
European Centre for Disease Prevention and Control
2018-2019
Università Cattolica del Sacro Cuore
2015
University of Trieste
2014
Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed estimate the burden of infections caused by public concern in countries EU European Economic Area (EEA) 2015, measured number cases, deaths, disability-adjusted life-years (DALYs).We estimated incidence with 16 antibiotic resistance-bacterium combinations from Antimicrobial Resistance Surveillance Network...
Specific foods and nutrients help prevent the progression of persistent high-risk human papillomavirus (hrHPV) infection to cervical cancer (CC). The aim this study was investigate dietary patterns which may be associated with hrHPV status risk high-grade intraepithelial neoplasia (CIN2+). Overall, 539 eligible women, including 127 CIN2+, were enrolled in a cross-sectional study, tested for infection. Food intake estimated using food frequency questionnaire. Logistic regression models...
Abstract Background This study aimed to investigate overall and sex-specific excess all-cause mortality since the inception of COVID-19 pandemic until August 2020 among 22 countries. Methods Countries reported weekly or monthly from January 2015 end June 2020. Weekly deaths were for Excess was calculated by comparing (observed deaths) against a baseline obtained 2015–2019 data same week month using two methods: (i) difference in observed rates between average (ii) expected deaths. Results...
Abstract Background The COVID-19 pandemic and the widespread adoption of virus control measures have inevitably disrupted efforts to address lifestyle risk factors for non-communicable diseases (NCD). This study aimed explore effects lockdown on all medicine pillars, namely diet, physical activity, sleep, stress, social support use risky substances. Methods was a cross-sectional convenient sample adults who resided in Cyprus during Spring 2020 lockdown. Participants completed an anonymous...
To examine the impact of COVID-19 pandemic on mortality, we estimated excess all-cause mortality in 24 countries for 2020 and 2021, overall stratified by sex age.
Several dietary agents, such as micronutrient and non-nutrient components, the so-called bioactive food have been shown to display anticancer properties influence genetic processes. The most common epigenetic change is DNA methylation. Hypomethylation of long interspersed elements (LINE-1) has associated with an increased risk several cancers, although conflicting findings also observed. aim present study was test hypothesis that a low adherence Mediterranean diet (MD) folate deficiency may...
Abstract Background Understanding the impact of burden COVID-19 is key to successfully navigating pandemic. As part a larger investigation on mortality impact, this study aims estimate Potential Years Life Lost (PYLL) in 17 countries and territories across world (Australia, Brazil, Cape Verde, Colombia, Cyprus, France, Georgia, Israel, Kazakhstan, Peru, Norway, England & Wales, Scotland, Slovenia, Sweden, Ukraine, United States [USA]). Methods Age- sex-specific death numbers from primary...
Emerging evidence suggests that air pollution increases the risk of cardiovascular disease (CVD) and metabolic disorders, adding to global burden attributable lifestyle behavioral factors. Although long interspersed nucleotide elements 1 (LINE-1) methylation has been associated with these no studies have simultaneously examined effects diet exposure on DNA methylation. Herein, we evaluated association particulate matter (PM aerodynamic diameters less than 10 mm) adherence Mediterranean Diet...
Bioactive food compounds have different effects on global DNA methylation, an epigenetic mechanism associated with chromosomal stability and genome function. Since the diet is characterized by a mixture of foods, we aimed to identify dietary patterns in women, evaluate their association long interspersed nuclear elements (LINE-1) surrogate marker methylation. We conducted observational cross-sectional study 349 women from Southern Italy, no history severe diseases. Dietary were derived...
Abstract Background To understand the impact of COVID-19 pandemic on mortality, this study investigates overall, sex- and age-specific excess all-cause mortality in 20 countries, during 2020. Methods Total, weekly for 2015–2020 was collected from national vital statistics databases. Excess 2020 calculated by comparing observed against expected estimated historical data (2015–2019) accounting seasonality, long- short-term trends. Crude age-standardized rates were analysed total sex-specific...
Antimicrobial resistance (AMR) is one of the biggest issues facing global public health. In 2017, Italy adopted its first National Action Plan on Resistance 2017-2020, which works through synergy between national, regional, and local levels. framework a Regional healthcare-associated infections AMR prevention, Sicilian Health Authority Region, Southern Italy, has implemented surveillance system antibiotic consumption in hospitals, community, rates (RRs) hospital settings. Data RRs have been...
The overuse of antimicrobials is one the main factors responsible for development and spread antimicrobial resistance, together with other causes, such as intra- inter-hospital resistant microorganisms infection control policies practices. objective present study to report trends Klebsiella pneumoniae Acinetobacter baumannii resistance indicators in an Italian intensive care unit (ICU) during a six-year period, from 2008 2013. Susceptibility data annual antibiotic consumptions ICU were...
Specific foods and nutrients help prevent the progression from persistent high-risk human papillomavirus (hrHPV) infection to cervical cancer (CC). We aimed focus on dietary patterns which may be associated with hrHPV status risk of high-grade intraepithelial neoplasia (CIN2+). Overall, 539 eligible women, including 127 CIN2+, were enrolled in a cross-sectional study, tested for infection. Food intakes estimated using food frequency questionnaire. Logistic regression models applied. Using...
Long Interspersed Nuclear Elements-1 (LINEs-1) methylation from white blood cells (WBCs) DNA has been proposed as biomarker associated with different types of cancer. The aim the present study was to investigate degree WBCs LINE-1 methylation, according high-risk Human Papilloma Virus (hrHPV) status in a healthy population, and association high-grade Cervical Intraepithelial Neoplasia (CIN2+) hrHPV positive women.Women abnormal cervical were enrolled classified by histological diagnosis...
Coronavirus disease 2019 (COVID-19) has significantly affected the well-being of individuals worldwide. We herein describe epidemiology COVID-19 in Republic Cyprus during first epidemic wave (9 March–3 May 2020). analyzed surveillance data from laboratory-confirmed cases, including targeted testing and population screening. Statistical analyses included logistic regression. During period, 64,136 tests (7322.3 per 100,000) were performed, 873 cases diagnosed, 20 deaths reported (2.3%)....
Objectives The aim of this cross-sectional study was to identify key factors associated with patient delay (PD), health system (HSD) and total (TOTD) in patients tuberculosis (TB) inform control programmes. Setting conducted four Italian regions 2014–2016. Data were obtained using a questionnaire including: sociodemographic lifestyle data, TB comorbidities, knowledge attitudes towards TB, stigma, access care health-seeking behaviours. Participants Patients’ inclusion criteria being diagnosed...