A5084566461- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Chemotherapy-induced organ toxicity mitigation
- RNA modifications and cancer
- Circular RNAs in diseases
- Body Composition Measurement Techniques
- Diet and metabolism studies
- Plant-derived Lignans Synthesis and Bioactivity
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- Nutritional Studies and Diet
- Phytochemical compounds biological activities
- Ubiquitin and proteasome pathways
- Multiple and Secondary Primary Cancers
- Ferroptosis and cancer prognosis
- Wnt/β-catenin signaling in development and cancer
- Radiology practices and education
- Epigenetics and DNA Methylation
- Microtubule and mitosis dynamics
- Long-Term Effects of COVID-19
- Hematopoietic Stem Cell Transplantation
- Genomics, phytochemicals, and oxidative stress
- Abdominal vascular conditions and treatments
- Polysaccharides and Plant Cell Walls
Second Affiliated Hospital of Xi'an Jiaotong University
2012-2025
Background Previous studies have shown inconsistent findings regarding the association of alcohol consumption with sarcopenia. Therefore, this study comprehensively investigated sarcopenia in a nationally representative sample US adults. Methods This population-based included adults aged 18 years and older from National Health Nutrition Examination Survey (NHANES) III. Alcohol exposure was defined as daily intake, drinking history, number days per week, frequency binge month. Weighted...
Background: As an important component of the NDC80 kinetochore complex, NUF2 is essential for kinetochore-microtubule attachment and chromosome segregation. Previous studies also suggested its involvement in development various kinds human cancers, however, expression functions hepatocellular carcinoma (HCC) are still unclear. Materials Methods: In present study, we aimed to test hypothesis that aberrant HCCs associated with cell growth. Results: Our results showed significantly elevated HCC...
Hepatocellular carcinoma (HCC) is a common abdominal cancer with dissatisfactory therapeutic effects. The discovery of cuproptosis lights on new approach for treatment and assessment. So far, there extremely limited research investigating the roles cuproptosis-related (CR) genes in cancers.A novel CR risk signature was constructed using Lasso regression analysis. Its prognostic value assessed via series survival analyses validated three GEO cohorts. effects tumor immune microenvironment...
Liver fibrosis is characterized by an exacerbated accumulation of deposition the extracellular matrix (ECM), and activation hepatic stellate cells (HSC) plays a pivotal role in development liver fibrosis. Periostin has been shown to regulate cell adhesion, proliferation, migration apoptosis; however, involvement periostin its transforming growth factor (TGF)-β1-induced HSC remains unclear. We used RT-PCR Western blot evaluate expression level tissues HSCs, respectively. Cell proliferation...
The nephrotoxicity of cisplatin limits its clinical application. Schizandrin B (SchB) has been demonstrated to have a variety potential cytoprotective activities. present study explored the molecular mechanisms by which SchB inhibits dichlorodiammine platinum (DDP)‑induced apoptosis HK‑2 proximal tubule epithelial cells. In vitro assays that increased viability cells, alleviated cis‑DDP‑induced activation caspase‑3, reduced and improved nuclear morphology Additionally, mechanism underlying...
Muscle quality index (MQI) is a novel indicator reflecting the of skeletal muscles. The association between MQI and development advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD) unknown. We investigated low among adults NAFLD using nationally representative sample US population. Adults who participated National Health Nutrition Examination Survey (NHANES) 2011–2014 were included. Sex-specific standard was used to define extremely MQI. Univariate multivariate...
Hepatocellular carcinoma (HCC) is one of the most common causes cancer-related deaths worldwide, especially in developing countries. Although advances surgical procedures and targeted medicine have improved overall survival patients with HCC, prognosis poor. Hence, there a need to identify novel therapeutic targets for HCC. Here, we report that expression RP11-909N17.2, novel, long, noncoding RNA (lncRNA), dysregulated HCC cell lines. Additionally, this study demonstrated RP11-909N17.2...
Abstract The protumor role of rhomboid domain‐containing 1 (RHBDD1) has been observed in multiple cancers. However, the relationship between RHBDD1 and pancreatic adenocarcinoma not addressed. This project focused on potential relevance adenocarcinoma. Bioinformatic analysis by publicly available data revealed that was abundantly expressed We further verified highly clinical specimens Kaplan–Meier curve demonstrated high‐RHBDD1 expression associated with poor prognosis patients. functional...
<title>Abstract</title> Muscle quality index (MQI) is a novel indicator reflecting the of skeletal muscles. The association between MQI and development advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD) unknown. We investigated low among adults NAFLD using nationally representative sample U.S. population. Adults who participated National Health Nutrition Examination Survey (NHANES) 2011–2014 were included. Sex-specific standard was used to define extremely MQI....