A5113887530- Head and Neck Surgical Oncology
- Oral and Maxillofacial Pathology
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer Immunotherapy and Biomarkers
- Immune cells in cancer
- Cancer-related molecular mechanisms research
- Endometriosis Research and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Second Language Learning and Teaching
- Corneal Surgery and Treatments
- Melanoma and MAPK Pathways
- Airway Management and Intubation Techniques
- EFL/ESL Teaching and Learning
- Sarcoma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Tracheal and airway disorders
- Ultrasound in Clinical Applications
- Radiomics and Machine Learning in Medical Imaging
- Dermatologic Treatments and Research
- Reconstructive Facial Surgery Techniques
- Tumors and Oncological Cases
- Congenital Heart Disease Studies
- Cancer Diagnosis and Treatment
- Uterine Myomas and Treatments
- Facial Nerve Paralysis Treatment and Research
National Clinical Research Center for Digestive Diseases
2025
Sichuan University
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
West China Hospital of Sichuan University
2024
Xi'an Jiaotong University
2024
Zhoushan Hospital
2024
National Clinical Research
2024
State Key Laboratory of Oral Diseases
2024
The malignant transformation of odontogenic keratocysts (OKC) into cancerous (COKC) is exceedingly rare, and its mechanisms remain poorly understood. Studies exploring the cellular heterogeneity, molecular pathways, clinical features COKC are limited. In this study, we performed single-cell RNA sequencing (scRNA-seq) on three samples integrated data with a public OKC dataset, identifying 22,509 single cells. Two COKC-specific epithelial subpopulations, Basal-C0-EXT1 Basal-C3-HIST1H3B, were...
Abstract The tumor immune microenvironment plays a critical role in progression and immunotherapy response, with the abundance composition of infiltrating cells serving as key determinants therapeutic outcomes. Given limitations direct experimental methods, computational deconvolution algorithms are widely applied to infer cell infiltration from bulk RNA-seq data. While such estimates have proven valuable for studying tumor–immune interactions, large-scale, systematic analyses across...
6090 Background: The effectiveness of neoadjuvant immunochemotherapy (NAIC) in treating resectable locally advanced oral squamous cell carcinoma (LAOSCC) remains uncertain, with a notable lack precise prognostic markers for NAIC outcomes. Methods: A single-arm prospective phase II trial was performed to assess the efficacy and safety NAIC, consisting 2 cycles intravenous camrelizumab (200 mg), albumin paclitaxel (260 mg/m²), cisplatin (75 mg/m²) administered every 3 weeks prior radical...
Oral mucosal malignant melanoma (OMMM) arises from melanocytes, and the most affected age, sex, site are 20 to 83 years, male, mucosa of hard palate maxillary gingiva, respectively. Despite several cases OMMM have been published in literature, arising around dental implant rarely reported.
This study investigated the etiology, clinical features, and management of acute hydrogen sulfide (H
Objective: To investigate the discharge outcome of external ventricular drainage(EVD) and conservative treatment in patients with severe intraventricular hemorrhage (SeIVH). Methods: From January 2011 to December 2016, SeIVH admitted General Hospital PLA Rocket Force Army received EVD were classified as group. According volume age, pair matched control Then we compared clinical moderate disability or less degree (mRS ≤3) death incidence 6) between two groups. Results: A total 361 IVH treated...
Lipomas occurring in the hard palate are extremely rare, and treating lipomas this area presents challenges due to thinness of soft tissue risk postoperative bony surface exposure. We present a case lipoma that was successfully removed using partial thickness flap dissection technique. In addition, we reviewed clinicopathological features 20 reported cases worldwide retrospectively analyzed clinical characteristics pathological types 68 oral China. The use demonstrates potential...
To describe the cases of oral and maxillofacial tumors (OMFT) resection defects reconstruction under submandibular intubation (SMI) performed in our institution; secondly, to systematically review analyze characteristics studies about SMI surgery estimate incidence rate complication. Data related all 6 patients included this study were prospectively collected from November 2016 2023. The tract for endotracheal tube was created by bluntly dissection area floor mouth. We an exhaustive search...
This study aims to evaluate the association between hysterectomy with bilateral salpingo-oophorectomy (HBSO) and depressive symptoms, exploring impact of different surgical approaches on severity depression. Data from 2006-2017 National Health Nutrition Examination Survey (NHANES) were used analyze relationship methods symptoms.This analyzed data 10,780 women aged 20-80 years, a diverse racial composition: 44.2% non-Hispanic White, 20.4% Black, 14.7% Mexican American, 11.0% Other Hispanic,...
This study reports an autoethnography of how the first author grappled with her EFL teacher identity crises in transformative periods. The sociocultural concept dramatic perezhivanie, i.e., one experiences a crisis through emotion-cognition dialectic, is employed as unit analysis. Through thematic analysis and perezhivanie semi-structured interviews other data including teaching portfolios, chatting records on WeChat (a local social media), emails, drafts manuscripts, reveals four...
Objective: To investigate the offline clinical effect of external diaphragm pacemaker (EDP) combination with High-flow nasal cannula oxygen therapy in postoperative severe cerebral hemorrhage patients. Methods: A total 123 patients tracheotomy and mechanical ventilation (MV) were selected, who admitted NICU PLA Rocket Force Characteristic Medical Center from October 2016 to December 2019. These randomly divided into (HFNC) group (n=63) HFNC+EDP (n=60). In HFNC group, was given off...