A5101278055- Nanoparticle-Based Drug Delivery
- Enzyme Catalysis and Immobilization
- Metal complexes synthesis and properties
- Layered Double Hydroxides Synthesis and Applications
- Inorganic Chemistry and Materials
- Analytical Chemistry and Chromatography
- RNA Interference and Gene Delivery
- Metal-Organic Frameworks: Synthesis and Applications
- Superconducting Materials and Applications
- Electrochemical sensors and biosensors
- Cancer-related molecular mechanisms research
- Pharmacological Effects of Natural Compounds
- Mesoporous Materials and Catalysis
- Advanced Biosensing Techniques and Applications
- Magnesium Oxide Properties and Applications
- Photonic Crystals and Applications
- Optical Coatings and Gratings
- Advanced Drug Delivery Systems
- Drug Transport and Resistance Mechanisms
- Nanoplatforms for cancer theranostics
- Magnetism in coordination complexes
- Circular RNAs in diseases
- Drug Solubulity and Delivery Systems
- Polyoxometalates: Synthesis and Applications
- solar cell performance optimization
Zhengzhou University
2024-2025
Wuhan National Laboratory for Optoelectronics
2025
Huazhong University of Science and Technology
2024-2025
Nanjing Tech University
2023-2024
Mudanjiang Medical University
2024
China Three Gorges University
2024
Henan University
2005-2023
Beijing University of Posts and Telecommunications
2023
Beijing University of Chemical Technology
2004-2021
Planar 1D photonic crystals (1DPhCs), owing to their bandgaps (PBGs) formed by unique structural interference, are widely utilized in light protection applications. Multifunctional coatings that integrate various management functions highly desired. In this study, we present the fabrication of dual-PBG 1DPhCs with high reflectance both blue and near-infrared (NIR) regions. The were constructed through alternating stacking hollow SiO2 (HS) nanoparticles hybridized poly(vinyl alcohol) (PVA),...
L-Tyrosine has been intercalated into NiAl, MgAl and ZnAl layered double hydroxides by coprecipitation. The structure composition of the materials have characterized X-ray diffraction (XRD) elemental analysis. It is found that intercalation can inhibit racemization L-tyrosine under influence sunlight, high temperature or ultraviolet light. Therefore, this material may potential application as a “molecular container” for storing transporting unstable chiral biomolecules pharmaceutical agents....
Esterification is one of the most important reactions in organic synthesis and industrial applications. The applications lipases esterification are increasingly widespread have high cumulative values. Mostly, catalytic cycle lipases, tunnel connecting active site to surface a protein plays significant role ligand transport. As unique conformational structure protein, could regulate performance via transportation. Therefore, lipase can be designed accordingly speed up transportation ligand,...
l-Aspartic acid (l-Asp) has been intercalated into magnesium−aluminum layered double hydroxides by coprecipitation. The structure and composition of the material have studied X-ray diffraction, inductively coupled plasma emission spectroscopy, elemental analysis. A schematic model proposed. Furthermore, thermal decomposition hybrid characterized in situ powder Fourier transform infrared thermogravimetry, differential analysis, 13C solid-state magic-angle spinning nuclear magnetic resonance,...
Abstract Recent scientific studies have highlighted the importance of long-chain noncoding RNAs (lncRNAs) in a variety metabolic diseases, but specific functions and mechanisms lncRNAs aberrant lipid synthesis associated with aging are unknown. In this work, we inspected effects on metabolism mice, as substantial evidence suggests that disturbs metabolism. The results revealed expression lncRNA Gm15232 was significantly elevated epididymal white adipose tissue mice compared to adult mice....
Poor interfacial quality and low refractive index contrast (Δn) are critical challenges for the development of high-performance one-dimensional photonic crystals (1DPhCs) via solution methods that impede their optical efficiency. Herein, we introduce an innovative approach by hybridizing hollow SiO2 with poly(vinyl alcohol), referred to as PHS, followed alternate assembly TiO2 spin-coating, achieving a 1DPhC Δn = 0.76 at wavelength 550 nm. This method circumvents need high-temperature...
Exploring a suitable immobilization strategy to improve catalytic efficiency and reusability of cellulase is great importance lowering the cost promoting industrialization cellulose-derived bioethanol. In this work, layered structure with thin PEG hydrogel as inner layer sodium polyacrylate (PAANa) brush outer was fabricated on low density polyethylene (LDPE) film by visible-light-induced graft polymerization. Two enzymes, β-glucosidase (BG) cellulase, were separately coimmobilized onto...
Cancerous tumors are still a major disease that threatens human life, with tumor multidrug resistance (MDR) being one of the main reasons for failure chemotherapy. Thus, reversing MDR has become research focus medical scientists.
Background: Improving poorly soluble drugs into druggability was a major problem faced by pharmaceutists. Nanosuspension can improve the of insoluble improving solubility, chemical stability and reducing use additives, which provided new approach for development application formulation. Paclitaxel (PTX) is well-known BCS class IV drug with poor solubility permeability. Also, many studies have proved that paclitaxel substrate membrane-bound efflux pump P-glycoprotein (P-gp), therefore it...
The pharmacokinetic profile of a drug can be different when delivered as nanosuspension compared with true solution, which may in turn affect the therapeutic effect drug. goal this study was to prepare itraconazole nanosuspensions (ITZ-Nanos) stabilized by an amphipathic polymer, polyethylene glycol-poly (benzyl aspartic acid ester) (PEG-PBLA), precipitation-homogenization, and ITZ-Nanos. particle size morphology were determined Zetasizer field emission scanning electron microscope (SEM),...
Hepatoma is the leading cause of death among liver diseases worldwide. Modern pharmacological studies suggest that some natural monomeric compounds have a significant effect on inhibiting tumor growth. However, poor stability and solubility, side effects are main factors limiting clinical application compounds.In this paper, drug-co-loaded nanoself-assemblies were selected as delivery system to improve chemical solubility Tanshinone II A Glycyrrhetinic acid, produce synergetic anti-hepatoma...
Glucose esters, heralded for their emulsifying and solubilizing properties, have found increasing application in food, pharmaceutical, cosmetic sectors. However, the environmental impact of chemical synthesis problem enzyme inactivation enzymatic hindered application. To this end, deep eutectic solvents (DESs) with stabilized activity better solubility properties are considered a promising solution. In study, 12 kinds hydrophilic DESs 22 hydrophobic were screened, we examined efficiency...