Yangyang Zheng

ORCID: 0009-0004-3826-4586
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Bacterial Infections and Vaccines
  • Esophageal Cancer Research and Treatment
  • Metastasis and carcinoma case studies
  • Gastric Cancer Management and Outcomes
  • Gallbladder and Bile Duct Disorders
  • Neuroblastoma Research and Treatments
  • Escherichia coli research studies
  • Ubiquitin and proteasome pathways
  • Microbial Natural Products and Biosynthesis
  • Renal and related cancers
  • Bacterial Genetics and Biotechnology
  • Genomics and Phylogenetic Studies
  • Esophageal and GI Pathology

Chinese Academy of Medical Sciences & Peking Union Medical College
2025

Hangzhou First People's Hospital
2024

Zhejiang Chinese Medical University
2024

Westlake University
2024

Ministry of Education of the People's Republic of China
2024

Nankai University
2024

China Agricultural University
2023

Abstract Ubiquitination is an important modification process in eukaryotic organisms, and ubiquitin ligase (E3) the most diversified component of this system. APIP6 (AvrPiz-t interacting protein 6) one E3s rice, involved recognition AvrPiz-t, effector from pathogen Magnaporthe oryzae , for initiation host defense against M. . However, structural detail how performs its function remains elusive. Here, we present crystal structure RING domain (i.e., E2-interaction domain) (APIP6-RING)....

10.1186/s42483-023-00186-w article EN cc-by Phytopathology Research 2023-07-11

Escherichia coli K1 is the leading cause of neonatal gram-negative bacterial meningitis, but pathogenesis E meningitis remains unclear. Blood-brain barrier (BBB) penetration a crucial step in development. Here, we uncovered role CsiR, GntR family regulator, virulence. During infection, csiR expression was induced due to derepression by Fur blood and human brain microvascular endothelial cells (HBMECs). CsiR positively regulated ilvB expression, which associated with branched chain amino acid...

10.1093/infdis/jiae157 article EN cc-by The Journal of Infectious Diseases 2024-03-26
Coming Soon ...