Xian-Jin Xu

ORCID: 0009-0004-5322-884X
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About
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Research Areas
  • Brucella: diagnosis, epidemiology, treatment
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • RNA and protein synthesis mechanisms
  • Bacteriophages and microbial interactions
  • Alzheimer's disease research and treatments
  • Galectins and Cancer Biology
  • Biomedical Research and Pathophysiology
  • Ferroptosis and cancer prognosis
  • Reproductive System and Pregnancy
  • RNA Research and Splicing
  • Autophagy in Disease and Therapy
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Burkholderia infections and melioidosis
  • Cancer Immunotherapy and Biomarkers

University of Science and Technology of China
2023-2024

Anhui University of Traditional Chinese Medicine
2018

Huazhong Agricultural University
2012-2016

MicroRNA (miRNA) is small non-coding RNA with approximate 22 nt in length.Recent studies indicate that miRNAs play significant roles pathogen-host interactions.Brucella organisms are Gram-negative facultative intracellular bacteria cause Brucellosis.Brucella strains infect macrophages and establish chronic infection by altering host life activities including apoptosis autophagy.Here, we report a comprehensive analysis of miRNA expression profiles mock-and Brucella-infected RAW264.7 cells...

10.7150/ijbs.3836 article EN cc-by-nc International Journal of Biological Sciences 2012-01-01

Context Qi Teng Xiao Zhuo granule (QTXZG) is a traditional Chinese medicine (TCM) used for therapeutic effects on chronic glomerulonephritis (CGN). However, the underlying mechanism remains unclear.Objective To investigate molecular of QTXZG CGN by proteomics.Materials and methods The model was induced in Sprague–Dawley rats injecting adriamycin (3.5 mg/kg, Day 1; 3.0 14) twice through tail vein. Urine samples were collected 21st day; divided randomly into control, adriamycin, administration...

10.1080/13880209.2023.2233998 article EN cc-by-nc Pharmaceutical Biology 2023-07-21

Abstract Purpose As the field of gynecological immunology increasingly focuses on reproduction, importance recurrent spontaneous abortion (RSA) is growing. The complex mechanisms underlying interaction between RSA and cancer are still not well understood. This study seeks to identify a new prognostic biomarker for cancer. Methods Weighted Gene Co-Expression Network Analysis (WGCNA), single-cell RNA sequencing (scRNA-seq), machine learning algorithms were utilized analysis decidua samples...

10.21203/rs.3.rs-3481541/v1 preprint EN cc-by Research Square (Research Square) 2023-10-28
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