Hanchen Chen

ORCID: 0009-0004-5323-6989
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About
Contact & Profiles
Research Areas
  • CRISPR and Genetic Engineering
  • Plant Virus Research Studies
  • Photosynthetic Processes and Mechanisms
  • Immune Response and Inflammation
  • Plant-Microbe Interactions and Immunity
  • Peptidase Inhibition and Analysis
  • Toxoplasma gondii Research Studies
  • DNA Repair Mechanisms
  • S100 Proteins and Annexins
  • Genomics, phytochemicals, and oxidative stress
  • RNA modifications and cancer
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Sanya University
2024-2025

Key Laboratory of Guangdong Province
2023

Agricultural Genomics Institute at Shenzhen
2023

Chinese Academy of Agricultural Sciences
2023

Huazhong Agricultural University
2021-2023

Shanghai Zhangjiang Laboratory
2023

Harbin Medical University
2018

Second Affiliated Hospital of Harbin Medical University
2018

Platelet-neutrophil interaction is well known for its role in inflammatory diseases; however, biological atherosclerosis (AS) progression remains unclear. Human peripheral blood neutrophils were obtained to compare toll-like receptor 4 (TLR4), tumor necrosis factor α (TNF-α), interleukin (IL)-1β and myeloid-related proteins 8/14 (Mrp8/14) levels 22 AS patients with those 18 healthy controls using quantitative real-time polymerase chain reaction (qRT-PCR) enzyme-linked immunosorbent assay...

10.1002/jcb.27844 article EN Journal of Cellular Biochemistry 2018-10-09

Abstract DNA replication stress threatens genome stability and is a hallmark of cancer in humans. The evolutionarily conserved kinases ATR (ATM RAD3-related) WEE1 are essential for the activation responses. Translational control an important mechanism that regulates gene expression, but its role responses largely unknown. Here we show ATR–WEE1 translation SUPPRESSOR OF GAMMA RESPONSE 1 (SOG1), master transcription factor required Arabidopsis thaliana. Through genetic screening, found loss...

10.1093/plcell/koad126 article EN The Plant Cell 2023-05-09
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