A5054953813- Additive Manufacturing Materials and Processes
- Cancer-related molecular mechanisms research
- High Entropy Alloys Studies
- MicroRNA in disease regulation
- Bone Tissue Engineering Materials
- Circular RNAs in diseases
- CRISPR and Genetic Engineering
- Cellular and Composite Structures
- High-Temperature Coating Behaviors
- Biosensors and Analytical Detection
- RNA modifications and cancer
- Bone and Dental Protein Studies
- RNA Research and Splicing
- Innovative Microfluidic and Catalytic Techniques Innovation
- Aluminum Alloys Composites Properties
- Extracellular vesicles in disease
- Identification and Quantification in Food
- Systemic Lupus Erythematosus Research
- High Temperature Alloys and Creep
- Antibiotic Resistance in Bacteria
- Additive Manufacturing and 3D Printing Technologies
- Polysaccharides and Plant Cell Walls
- Advanced Welding Techniques Analysis
- Nanoporous metals and alloys
- dental development and anomalies
Affiliated Hospital of Youjiang Medical University for Nationalities
2015-2025
Baise University
2022-2024
Guangxi Center for Disease Prevention and Control
2024
Shanghai Jiao Tong University
2021-2023
Guilin Medical University
2019-2020
Youjiang Medical College for Nationalities
2017-2020
Guangxi University
2018-2019
China Pharmaceutical University
2014-2016
Background Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a severe nosocomial threat, prompting need for efficient detection methods. Traditional approaches, such as bacterial culture and PCR, are time-consuming cumbersome. The CRISPR-based gene editing system offered potential approach point-of-care testing of CRAB. Methods We integrated recombinase polymerase amplification (RPA) CRISPR-Cas12a to swiftly diagnose CRAB-associated genes, OXA-51 OXA-23 . This multiplex...
Introduction: Salmonella was one of the most common bacteria that caused foodborne illness, with S. typhimurium ( ) and enteritidis infections accounting for more than 75% human salmonella infections. Methods: In this study, we developed a method dual recombinase polymerase amplification (RPA) combined lateral flow dipstick rapid detection in clinical specimens (stool). Results: The entire reaction process, including result reading, could be completed within 65 min. limits pure culture...
The pore strategy is one of the important factors affecting biomedical porous scaffold at same porosity. In this work, scaffolds were designed based on triply periodic minimal surface (TPMS) structure under porosity and different strategies (pore size continuous gradient distribution) successfully prepared using a novel Ni46.5Ti44.5Nb9 alloy selective laser melting (SLM) technology. After that, effects microstructure, mechanical properties, permeability systematically investigated. results...
Background: The incidence of obesity-associated decline in male fertility has increased over the years. Lycium barbarum polysaccharide (LBP), a natural plant extracted from Chinese herb L. shown promising therapeutic effects overcoming same. Aim: This study aimed to investigate protective effect LBP on testes obese mice. Methods: Following administration high-fat diet-induced mice for 35 days, serum, sperm, and testis samples were obtained subsequent experiments. Biochemical analysis sex...
Abstract Growth arrest‐specific 5 (GAS5) is a kind of long non‐coding RNAs (lncRNAs). Previous studies showed that down‐regulation LncRNA‐GAS5 was involved in the development systemic lupus erythematosus (SLE). However, regulatory mechanism down‐expressed SLE remains obscure. In this study, we aimed to investigate association polymorphism with risk. And further explore how occurrence SLE. Here, evaluated relationship between risk for and 5‐base pair (AGGCA/‐) insertion/deletion (I/D)...
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Introduction: Ischemic stroke (IS) is a global health concern, often tied to dyslipidemia and vascular endothelial dysfunction. MicroRNA-34a (miR-34a) was reported be up-regulated in the blood samples of patients with IS, but specific role miR-34a methylenetetrahydrofolate reductase (MTHFR) IS remains elucidated. Methods: We studied 143 subjects: 71 patients, 72 healthy controls. Human umbilical vein cells (HUVECs) were cultured transfected mimic, inhibitor, or negative control. The...
Carbapenem resistant Klebsiella pneumoniae (CRKP) can cause serious hospital- and community-acquired infections. Treatment for CRKP infection is limited, resulting in prolonged hospitalization high consultation costs. The KPC genotype has the highest detection rate of CRKP, its mortality higher than overall CRKP. However, traditional testing methods have disadvantages such as long time reliance on complex sophisticated instruments, which are not conducive to rapid screening Therefore, this...
Background: Lycium barbarum polysaccharide (LBP) has been reported to contribute the recovery of male hypogonadism and infertility. Aim: The aim current study was investigate underlying mechanisms LBP on infertility recovery. Methods: Recently, it is that cell apoptosis mediated by endoplasmic reticulum stress (ERS) distinguished from death reporters mitochondria pathway, which could induce independently. possible signaling were investigated using diversified molecular biology techniques,...
The expression of miR-127 has been reported to be decreased in the breast tissue patients with cancer (BRC). However, mechanism involvement pathogenesis BRC is still unclear and requires urgent clarification.To explore role BRC.In this study, we measured blood samples 60 controls, investigated influence on viability apoptosis MCF-7 MDA-231 cells, identified a target gene, determined level gene controls.We found that was significantly plasma compared controls. Additionally, upregulation cells...