A5044721259- Nanoplatforms for cancer theranostics
- Metal-Organic Frameworks: Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Boron and Carbon Nanomaterials Research
- Advanced Control Systems Optimization
- Scheduling and Optimization Algorithms
- Process Optimization and Integration
- Dendrimers and Hyperbranched Polymers
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Radiation Dose and Imaging
- Diet and metabolism studies
- Graphene research and applications
- Covalent Organic Framework Applications
- Advanced X-ray and CT Imaging
- Conducting polymers and applications
- Carbon and Quantum Dots Applications
- Traffic control and management
- Electrical and Thermal Properties of Materials
- Diabetes Management and Research
- RNA Interference and Gene Delivery
- High-Temperature Coating Behaviors
- Advanced Nanomaterials in Catalysis
First Affiliated Hospital Zhejiang University
2025
Hunan University
2020-2024
China Agricultural University
2024
Harbin Veterinary Research Institute
2024
Chinese Academy of Agricultural Sciences
2024
Shandong University of Technology
2023-2024
Second Xiangya Hospital of Central South University
2024
Guangzhou University of Chinese Medicine
2024
China-Japan Friendship Hospital
2024
Beijing University of Chinese Medicine
2024
A cascade amplification release nanoparticle (CARN) is constructed by the coencapsulation of β-lapachone and a reactive-oxygen-species (ROS)-responsive doxorubicin (DOX) prodrug, BDOX, in polymeric nanoparticles. Releasing first from CARNs selectively increases ROS level cancer cells via NAD(P)H:quinone oxidoreductase-1 (NQO1) catalysis, which induces DOX overcomes multidrug resistance (MDR) cells, producing remarkably improved therapeutic efficacy against MDR tumors with minimal side effects.
Abstract Hexagonal boron nitride (h‐BN) nanomaterials are a rising star in the field of biomedicine. This review presents an overview progress h‐BN for biological applications. It begins with general introduction structural characteristics h‐BN, followed by brief its physical and chemical properties, including thermal, band mechanical reactivity, biodegradability biocompatibility, then emphasizes on recent biomedical applications drug delivery, neutron capture therapy (BNCT), bioimaging...
Abstract Fuel cell vehicles powered by hydrogen are particularly attractive and competitive among rapidly developing new energy‐driven automobiles. One critical problem for this type of is the high cost storage due to lack efficient low‐pressure technologies. In frame development physisorption‐relied materials, attention has mostly been paid textural designs porous including specific surface area, pore volume, size. However, based on physisorption mechanism, adsorption energy a material...
Nanomaterials having enzyme-like activities are recognized as potentially important self-therapeutic nanomedicines. Herein, a peroxidase-like artificial enzyme is developed based on novel biodegradable boron oxynitride (BON) nanostructures for highly efficient and multi-mode breast cancer therapies. The BON nanozyme catalytically generates cytotoxic hydroxyl radicals, which induce apoptosis of 4T1 cells significantly reduce the cell viability by 82% in 48 h. In vivo experiment reveals high...
Abstract Wireless charging energy storage devices eliminate bulky wires of wearable electronics. However, rigid shape and specific restrict their applications in space‐limited portable Herein, an all‐carbon fiber supercapacitor is presented that features shape‐adjustable, packable, energy‐controllable wireless functions. With the unique on‐dimensional circuit structure, maximum transfer efficiency from electrical received by unit to output can reach up ≈60.8%, meanwhile this integrated...
Covalent organic frameworks (COFs) have emerged as promising drug carriers due to their structural variability, inherent porosity, and customizable functions. However, most COFs used in delivery suffer from low cellular bioavailability poor luminescence properties. In this study, we designed a series of size-tunable, crystalline, red-fluorescent COF nanospheres (COFNSs) for trackable anticancer delivery. The semiconducting COFNSs were prepared by condensations 1,3,5-triformylbenzene (TFB)...
<h2>Summary</h2><h3>Background</h3> The sequential anti-osteoporotic treatment for women with postmenopausal osteoporosis (PMO) is important, but the order in which different types of drugs are used confusing and controversial. Therefore, we performed a network meta-analysis to compare efficacy safety available treatments explore most efficacious strategy long-term management osteoporosis. <h3>Methods</h3> In this meta-analysis, searched PubMed, EMBASE, Web Science, Cochrane Library,...
Introduction Glioblastoma (GBM) represents the most aggressive and prevalent form of primary malignant brain tumor in adults, with surgical intervention being treatment modality. To enhance outcomes extend patient survival, we have engineered a dual-modality MRI/FI contrast agent known as PL002 to aid management GBM. Methods In this study, an orthotopic glioma model was established mice via intracranial injection U-87 MG cells. Subsequently, animals were intravenously injected placed 7.0T...
Implantable devices hold promise for revolutionizing personalized healthcare, but the inherent invasiveness of implantation surgeries, among other obstacles, hinders their widespread application. In this work, we present an implantable wireless glucose monitor made with on shape-memory electronic device (SMED) that can be implanted minimal invasiveness. The is fabricated by printing inductive-capacitive (LC) circuit and a poly(3-aminophenylboronic acid) (PAPBA)/glucose oxidase (GOx)/graphene...
Abstract Background The genus Providencia includes species of ecological and clinical significance, with some acting as opportunistic pathogens in hospital-acquired infections such urinary tract infection (UTI). However, overlapping phenotypic traits genetic similarities pose challenges for accurate characterization. This study exemplifies this challenge by identifying a novel isolate through genomic analysis. Results In study, strain PAZ2 was isolated from the urine sample hospitalized...
Current treatment guidelines for Mycobacterium abscessus complex (MAB) infections recommend macrolides (clarithromycin/CAM and azithromycin/AZM) as cornerstone therapies, considering them clinically interchangeable without distinction. This study evaluated the comparative in vitro activity of clarithromycin (CAM) azithromycin (AZM) against 146 clinical isolates organisms. MIC distributions revealed significantly higher resistance to AZM (94.5% resistant at ≥8 μg/mL) compared CAM (77.4%...
ABSTRACT Current treatment guidelines for Mycobacterium abscessus complex (MAB) infections recommend macrolides (clarithromycin/CAM and azithromycin/AZM) as cornerstone therapies, considering them clinically interchangeable without distinction. This study evaluated the comparative in vitro activity of clarithromycin (CAM) azithromycin (AZM) against 146 clinical isolates organisms. MIC distributions revealed significantly higher resistance to AZM (94.5% resistant at ≥8 μg/mL) compared CAM...
Purpose: To identify the population susceptible to reactive hypoglycemia and explain possible reasons for their susceptibility. Methods: Ninety-four patients were divided into normal weight, overweight obese groups before a 75-gram prolonged oral glucose tolerance test (POGTT). The incidence of (blood ≤ 3.1 mmol/L or 55 mg/dL at points 0– 4 hours) was compared among three groups, blood insulin levels monitored simultaneously from 0 - hours assess level resistance sensitivity. Furthermore,...
A hyaluronic acid-coated and albumin-templated MnO<sub>2</sub>and polydopamine hybrid nanoparticle for tumor-targeting imaging therapy.
Therapeutic nanoplatforms are widely used in the diagnosis and treatment of breast cancer due to merits enabling high soft-tissue resolution availability numerous therapeutic nanoparticles. It is thus vital develop multifunctional theranostic nanoparticles for visualization dynamic monitoring tumor therapy. In this study, we designed a manganese-based hypericin-loaded polyester dendrimer nanoparticle (MHD) magnetic resonance imaging (MRI) hypericin-based photodynamic therapy (PDT)...