- Neurogenetic and Muscular Disorders Research
- Sarcoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Neuroendocrine Tumor Research Advances
- Bone Tumor Diagnosis and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cardiomyopathy and Myosin Studies
- Vascular anomalies and interventions
- Icing and De-icing Technologies
- Peripheral Nerve Disorders
- Robotics and Automated Systems
- MRI in cancer diagnosis
- Tuberous Sclerosis Complex Research
- Fatty Acid Research and Health
- Radical Photochemical Reactions
- Industrial Automation and Control Systems
- IgG4-Related and Inflammatory Diseases
- High-Energy Particle Collisions Research
- Spinal Dysraphism and Malformations
- Air Quality and Health Impacts
- Environmental Changes in China
- Air Quality Monitoring and Forecasting
- Ferroptosis and cancer prognosis
- Aerodynamics and Fluid Dynamics Research
- Quantum Mechanics and Non-Hermitian Physics
Xidian University
2025
The First Affiliated Hospital, Sun Yat-sen University
2018-2025
Sun Yat-sen University
2018-2025
Tianjin Chest Hospital
2023-2025
Tianjin University
2025
Tianjin Medical University
2024
Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital
2019-2023
Wuxi No.2 People's Hospital
2023
University of Benin
2023
Wuhu Hit Robot Technology Research Institute
2022
Spinal muscular atrophy (SMA) is one of the most common monogenic neuromuscular diseases, and pathogenesis mechanisms, especially brain network topological properties, remain unknown. This study aimed to use individual-level morphological analysis explore neural mechanisms in SMA.
Purpose: Clinical studies have demonstrated the intricate association between onset and progression of obstructive sleep apnea (OSA) activation inflammatory cascade reaction. This study delves into investigating causal links 91 circulating proteins (CIPs) OSA through application Mendelian randomization (MR) techniques. Methods: Utilizing genetic data on sourced from Finnish Biobank (FinnGen) Genome-wide Association Studies (GWAS) European population, alongside summary-level GWAS CIPs 14,824...
Cancer stem cells (CSCs) possess the ability to self-renew and exhibit high differentiation potential, they have been proven be responsible for maintenance, growth, metastasis of tumors. As such, accurate identification targeted therapy CSCs are great importance in clinical treatment. Here, a dual-targeted light-responsive nanoprobe is presented, utilizing reconstructed mesoporous SiO2 binary fatty acid eutectic mixture gold porous shell. The shell sustains large absorption cross-section,...
Several studies have shown that spinal muscular atrophy (SMA) is not limited to lower motor neurons. This cross-sectional study aimed quantitatively investigate the gray matter (GM) alterations in patients with SMA types 2 and 3. a study. T1 T2 maps were extracted from synthetic magnetic resonance imaging (SyMRI) compared between healthy controls (HC). Between-group comparisons made type The association brain regions significantly altered values clinical measurements evaluated Pearson...
Background: As urbanization progresses, the resulting air pollution has become an increasingly severe public health issue, known to exacerbate respiratory and cardiovascular diseases. Recent studies suggest that it may also affect blood coagulation mechanisms. In this study, Mendelian randomization (MR) analysis was used explore causal relationship between pulmonary embolism (PE). Methods: This study employs MR techniques, using genetic variants associated with exposure assess their impact...
The co-occurrence of type 1 autoimmune pancreatitis (AIP) and pancreatic tumor (PaT) has been previously reported. Pure AIP cases have favorable prognosis are primarily treated with steroids, while PaT associated poor where the primary management is resection. However, it's a challenge to timely identify concurrent in because their similar clinical radiological manifestations.We retrospectively reviewed data two medical centers from January 2010 April 2019. inclusion criteria were as...
An efficient, simple and versatile synthesis of biologically valuable benzo[c]chromen-6-ones is achieved using a tandem photo-thermal-photo reaction sequence starting from 3,4-dichlorocoumarins 1,3-butadiene. In this concise one-pot protocol, neither metal catalyst nor peroxide promoter needed the products can be purified through recrystallization in most cases. The consists photo-induced [4 + 2] [2 cycloadditions, silica gel promoted elimination HCl electrocyclic cyclobutene ring opening...
In this study, Au+Au collisions with the impact parameter of $0 \leq b 12.5$ fm at $\sqrt{s_{NN}} = 200$ GeV are simulated by AMPT model to provide preliminary final-state information. After transforming these information into appropriate input data (the energy spectra charged hadrons), we construct a deep neural network (DNN) and convolutional (CNN) connect observables parameters. The results show that both DNN CNN can reconstruct parameters mean absolute error about $0.4$ behaving slightly...
In this paper, we introduce a new definition of fractional derivative which contains factor, and its physical meanings are given. When studying the Schrödinger equation (FSE) with form derivative, result shows that under description time FSE probability finding particle in whole space is still conserved. By using to construct FSE, achieve continuous transition from standard one. applying an infinite symmetrical square potential well, find density distribution loses spatial symmetry kind...
The aim of the study is to investigate value computed tomography (CT) radiomics features discriminate liver metastases (LMs) digestive system neuroendocrine tumors (NETs) from carcinoma (NECs).Ninety-nine patients with LMs neoplasms 2 institutions were included. Radiomics extracted portal venous phase CT images by Pyradiomics and then selected using t test, Pearson correlation analysis, least absolute shrinkage selection operator method. score (Rad score) for each patient was constructed...
As a new entity included in the 4th edition of WHO classification tumours soft tissue and bone 2013, hybrid peripheral nerve sheath are benign composite neoplasms that demonstrate features more than one type tumour, with wide age distribution predilection for superficial location. Those involving deep sites relatively rare. To best our knowledge, only case primary intraosseous has been documented. In this article, we report another occurring different clinical, radiological pathological from...
The study investigated brain structure changes in type 2 and 3 SMA patients their correlation with the severity of clinical symptoms. MRI examinations were performed on 3.0T scanner 3D T1W data analyzed using FreeSurfer. result showed had extensive, multifocal, symmetrical gray white matter degeneration. postcentral gyrus is strongly associated symptom patients. It might be explained by fact that motor neurons exhibit functional alterations, leading to selective neuron loss. So it crucial...
Motivation: The exercise-tailored diffusion-weighted imaging (DWI) protocol has never been implemented to assess sex differences in age-related muscle quality the healthy population. Goal(s): To investigate feasibility of kinetics on DWI during exercise for assessing quality. Approach: This study recruited 87 participants with 174 legs imaged and assessed Results: Males females showed different pattern plantar flexion. Impact: An MR can be
Herein, we first reported a case of undifferentiated sarcoma with epithelioid features harboring TFE3 amplification. A 66-year-old woman history chronic lymphocytic leukemia and chemotherapy presented 4 cm palpable nodule in the left lower leg. Microscopically, large tumor cells remarkable pleomorphism small round intermingled each other diffuse sheet or hemangiopericytoma-like vascular growth pattern. Atypical mitotic figures lymph node metastasis were found while necrosis was absent....
Design content includes the choice of controller, design external wiring, PLC programming.According to movement process, write program.The program has four components, initialization program, manual operation automatic return origin and working program.Simulating debugging work piece on stepping conveyor was moved processing machine tool worktable.The device can in succession, improve environment, reduce labor intensity, level automation.