A5013661024- Electromagnetic Compatibility and Noise Suppression
- Complement system in diseases
- Radio Frequency Integrated Circuit Design
- Blood groups and transfusion
- Microwave Engineering and Waveguides
- Acute Myeloid Leukemia Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Vascular Tumors and Angiosarcomas
- Hematological disorders and diagnostics
Sungkyunkwan University
2011-2024
Samsung Medical Center
2011-2022
Background Decitabine was evaluated for its efficacy and safety in Korean patients with myelodysplastic syndrome IPSS score of 0.5 or over.Design Methods 20 mg/m2/day given intravenously over one hour five consecutive days every four weeks. The primary end point overall response rate.Results A total 101 were analyzed. International Prognostic Scoring System risk category Intermediate-2/High 47.5%. median 5 courses (range 1–18) delivered. rate 55.4% (13 complete responses, partial response,...
In this paper, we propose a method for measuring the third-order intermodulation distortion (IMD3) components of circuits in D-band (110~170 GHz) on wafers. Two independent signal sources were combined using directional coupler to generate two-tone signal. Frequency downconversion mixers and attenuators used minimize impact setup IMD3 measurements device under test. The powers both fundamental frequency prototype power amplifier chip measured which enhanced reliability by comparing with...
Background: SB12, a proposed eculizumab biosimilar, is humanized monoclonal antibody that blocks complement C5 cleavage, thereby inhibits terminal complement-mediated intravascular hemolysis. Aims: The randomized, double-blind, multicenter, cross-over study was aimed to demonstrate comparable clinical efficacy by evaluating the lactate dehydrogenase (LDH), safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of SB12 reference (ECU) in paroxysmal nocturnal hemoglobinuria...