A5062732456- Inflammatory Bowel Disease
- Chronic Lymphocytic Leukemia Research
- Cutaneous Melanoma Detection and Management
- MRI in cancer diagnosis
- Immunodeficiency and Autoimmune Disorders
- Microscopic Colitis
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Monoclonal and Polyclonal Antibodies Research
- Nonmelanoma Skin Cancer Studies
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Biliary and Gastrointestinal Fistulas
- Aortic aneurysm repair treatments
- Tracheal and airway disorders
- Obstructive Sleep Apnea Research
- Psoriasis: Treatment and Pathogenesis
- Viral Infections and Immunology Research
- Vascular Tumors and Angiosarcomas
- Systemic Sclerosis and Related Diseases
- Cancer Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Infectious Diseases and Tuberculosis
European Institute of Oncology
2025
Istituto De Angeli (Italy)
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2023
Policlinico San Matteo Fondazione
1993-2023
Vita-Salute San Raffaele University
1992-2021
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2019
University of Sassari
2016-2019
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2008-2017
Azienda Ospedaliera San Gerardo
1999-2016
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2014-2016
A prospective study was designed to determine the sensitivity and specificity of nonenhanced T2-weighted contrast material-enhanced T1-weighted magnetic resonance (MR) imaging in assessing depth myometrial invasion patients with proved endometrial cancer. In 56 consecutive clinically determined early-stage disease, findings two MR techniques were compared results histologic examination surgical specimens. Myometrial classified as absent (stage IA), superficial IB), or deep IC). assessment...
The accuracy of nonenhanced spin-echo (SE) T2-weighted and contrast material-enhanced SE T1-weighted magnetic resonance (MR) imaging in assessing the degree local tumor invasion was determined prospectively 53 consecutive patients with clinically established early-stage carcinoma cervix. With a 0.5-T superconducting unit, pulse sequences 2,000/90 (repetition time msec/echo msec) for images 500/20 were used. In all cases, findings two MR techniques compared results histologic examination...
Endogenous retroviruses (HERV) are believed to be pathogenic in several autoimmune diseases. Among them, HERV-K viruses have been reported recently involved the pathogenesis of rheumatoid arthritis (RA). In this study we explored role humoral immune response against as a potential pathogenetic mechanism RA. Four different peptides from extracellular portion env protein (env-su19-37 , env-su109-126 env-su164-186 env-su209-226 ) were selected by bioinformatic analysis on basis their putative...
Recent reports have revealed the therapeutic potential of cell-mediated immunity in neoplasms such as cutaneous squamous cell carcinoma (SCC).To define antigenic coexpression regulatory T cells (Tregs) and plasmacytoid dendritic (pDCs) assess CD8(+) /Foxp3(+) CD25(+) ratio at peritumoral intratumoral levels order to investigate a correlation with aggressiveness SCC tumours.We evaluated content distribution Foxp3(+) Treg CD123(+) pDC infiltration assessed 40 SCCs (20 well-differentiated, G1;...
Abstract Background Basal cell carcinoma (BCC) is a non‐melanocytic skin tumour with high risk of recurrence after incomplete treatment, especially the aggressive subtypes (basosquamous, micronodular and morphea BCC). The percentage also depends on anatomical site tumour. Nose–cheek fold, paranasal retroauricular fold internal canthus are considered to be critical sites. Objective aim this study was report rates for BCC treated Mohs micrographic surgery (MMS). Material Methods We...
TPS10625 Background: Breast cancer (BC) prevention in high-risk women is crucial. Tamoxifen, despite its efficacy, has limited use due to side effects. Low-dose tamoxifen (LDT) shown much better balance between BC risk reduction and adverse Additionally, lifestyle interventions (LI) like intermittent caloric restriction (ICR) physical activity may further reduce by modulating factors such as mammographic density (MD) sex hormone-binding globulin (SHBG) levels, which we showed correlated with...
To assess the potential role of magnetic resonance (MR) imaging in follow-up evaluation small hepatocellular carcinoma (HCC) treated with percutaneous ethanol injection (PEI), 31 patients a single HCC lesion less than 3.0 cm diameter underwent MR at 0.5 T before and after treatment. Posttreatment included contrast material-enhanced computed tomography (CT) fine-needle biopsy all cases. The most important characteristic lesions was hypointensity on T2-weighted images cases (27 31) which...
In recent years, vitamin D3 analogues have become one of the most widely prescribed topical treatments for mild or moderate chronic plaque psoriasis. These molecules are effective and safe, but their exact mechanism action is not completely understood. vitro studies shown that decrease proliferation induce differentiation keratinocytes, strong immunomodulating effects, there no conclusive data about apoptosis. The aim this study was to evaluate differences in apoptotic response between...
High hepatocyte proliferation has been recently proposed as a risk factor for the development of hepatocellular carcinoma (HCC). The aim this study was to assess whether is an independent HCC when considered together with clinical and demographic characteristics.We retrospectively evaluated 97 consecutive patients histological diagnosis cirrhosis preserved liver function, enrolled in surveillance program early HCC. Hepatocyte by flow-cytometric analysis samples collected at time cirrhosis....
Chronic venous leg ulcers represent an urgent and increasing problem for public health. The use of skin autografts results in a greater therapeutic success healing chronic ulcers.A simple method autografting that could permit wider grafts outpatients is needed. A new technique allowing one-step process, without complex surgical procedures or expensive technical supplies, presented.A small, full-thickness specimen taken from the patient finely minced spread on his ulcer bed to cover surface...
Cutaneous metastasis from neuroendocrine carcinomas of visceral origin is rarely described in indexed literature. The primary sites include: lung (Wick et al., J Am Acad Dermatol 1985; 13: 134), larynx (Zambruno Ann Venereol 1989; 116: 855; Schmidt Laryngol Otol 1994; 108: 272; Guerzider Pathol 1991; 11 (4): 253), mediastinum (Yoshimasu 2001; 28 (3): 168), uterus (Fogaca Cutan 1993; 20: 455), and thymus 134).In this report, the authors present clinical, histological, immunohistochemical,...
See also: Commentaire de travail E. Masci et al., pp. 1076Endoscopy 2007; 39(12): 85-86DOI: 10.1055/s-0032-1308892
Preclinical studies provided a strong rationale for pathophysiological link between cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) and secondary brain injury after subarachnoid hemorrhage (SAH-SBI). In single-center prospective observational clinical study, external ventricular drain (EVD) based CSF-Hb proved to be promising biomarker monitor SAH-SBI. The primary objective of HeMoVal study is prospectively validate association EVD SAH-SBI during first 14 days post-SAH. Secondary...
<i>Background/Aim:</i> The guidelines of the British Photodermatology Group for topical treatment with psoralen and ultraviolet light (PUVA) recommend starting UVA doses between 0.2 0.5 J/cm<sup>2</sup>, according to phototype. Our purpose was evaluate therapeutic efficacy tolerability bath PUVA, 8-methoxypsoralen (8-MOP), by using lower doses, regardless <i>Methods:</i> We compared 2 groups patients (group 1: n = 10, group 2: 20) chronic plaque-type...
We describe two nonconsanguineous white patients with multiple pigmented basal cell carcinomas (BCCs) that were histopathologically confirmed. The first patient had calcification of the cerebral falx, keratocysts in jaw, and other malformations cranial finger bones. second presented dermoid cysts, mandible, agenesis left kidney. Both palmar pits. denied any family history cutaneous tumours. On dermatoscopic examination 1, multiple, bluish, confluent large globules seen. blue ovoid globules,...