Donnamae Klocek

ORCID: 0009-0004-9066-005X
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About
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Research Areas
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Viral Infections and Vectors
  • Plant Virus Research Studies
  • Plant and Fungal Interactions Research
  • Insect-Plant Interactions and Control
  • Insect and Pesticide Research
  • Plant Disease Resistance and Genetics
  • Vector-Borne Animal Diseases

University of Ostrava
2022-2024

RNA viruses play an important role in Leishmania biology and virulence. Their presence was documented three (out of four) subgenera. Sauroleishmania reptiles remained the only underinvestigated group. In this work, we analyzed viral occurrence spp. detected out seven isolates under study. These were two families-Narnaviridae Totiviridae. Phylogenetic inferences demonstrated that totiviruses from L. adleri tarentolae group together within a larger cluster LRV2s, while narnavirus gymnodactyli...

10.1007/s00436-023-07928-x article EN cc-by Parasitology Research 2023-07-25

Abstract Trypanosomatids (Euglenozoa) are a diverse group of unicellular flagellates predominately infecting insects (monoxenous species) or circulating between and vertebrates plants (dixenous species). Monoxenous trypanosomatids harbor wide range RNA viruses belonging to the families Narnaviridae, Totiviridae, Qinviridae, Leishbuviridae, putative tombus-like viruses. Here, we focus on subfamily Blastocrithidiinae, previously unexplored divergent monoxenous comprising two related genera:...

10.1093/ve/veae037 article EN cc-by Virus Evolution 2024-01-01

Abstract Background Trypanosomatids are parasitic flagellates well known because of some representatives infecting humans, domestic animals, and cultural plants. Many trypanosomatid species bear RNA viruses, which, in the case human pathogens Leishmania spp., influence course disease. One close relatives leishmaniae, Leptomonas pyrrhocoris , has been previously shown to harbor viruses groups not documented other trypanosomatids. At same time, this a worldwide distribution high prevalence...

10.1186/s12915-023-01687-y article EN cc-by BMC Biology 2023-09-12

Leishmania spp. represent human pathogens that cause leishmaniasis, a widespread parasitic disease with mild to fatal clinical manifestations. Some strains of leishmaniae bear leishmaniaviruses (LRVs), and this has been shown aggravate course.

10.1128/msphere.00335-22 article EN cc-by mSphere 2022-08-09

Leishmania RNA virus 1 (LRV1) is commonly found in South American parasites belonging to the subgenus Viannia, whereas 2 (LRV2) was previously thought be restricted Old-World pathogens of Leishmania.In this study, we investigated presence LRV2 strains (L.) infantum, causative agent visceral leishmaniasis (VL), originating from different hosts, clinical forms, and geographical regions.A total seventy-one isolates were screened for using semi-nested reverse transcription-polymerase chain...

10.1590/0074-02760230071 article EN cc-by Memórias do Instituto Oswaldo Cruz 2023-01-01

Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing variety vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures visceral organs. disease exacerbated if parasite harbors RNA viruses (LRVs) Pseudototiviridae . Screening novel isolate L braziliensis , we revealed it possesses not toti-, but bunyavirus Leishbuviridae To best our knowledge, this very first...

10.1371/journal.pntd.0012767 article EN cc-by PLoS neglected tropical diseases 2024-12-27
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