Guanghui Chen

ORCID: 0009-0005-2956-4402
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Musculoskeletal pain and rehabilitation
  • Myofascial pain diagnosis and treatment
  • Spine and Intervertebral Disc Pathology
  • Cervical and Thoracic Myelopathy
  • Tea Polyphenols and Effects
  • Pain Management and Placebo Effect
  • S100 Proteins and Annexins
  • Lung Cancer Treatments and Mutations
  • Diet and metabolism studies
  • Metabolomics and Mass Spectrometry Studies
  • Plant and animal studies
  • Connective tissue disorders research
  • Cancer Mechanisms and Therapy
  • Heterotopic Ossification and Related Conditions
  • Tryptophan and brain disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Plant Parasitism and Resistance
  • Bioinformatics and Genomic Networks
  • Ecology and Vegetation Dynamics Studies
  • Neurological Complications and Syndromes
  • Virtual Reality Applications and Impacts
  • Cancer-related gene regulation
  • Liver Disease Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Acupuncture Treatment Research Studies

Guangxi University of Chinese Medicine
2022-2025

Guangxi University
2024-2025

Peking University Third Hospital
2021-2025

Peking University
2004-2025

Hubei University of Medicine
2012-2024

The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
2022-2024

Xiangyang Central Hospital
2024

Chongqing Medical University
2014

Xishuangbanna Tropical Botanical Garden
2001

Non-alcoholic fatty liver disease (NAFLD) poses a significant global public health concern. Liupao tea (LPT) is Chinese national geographical indication product renowned for its lipid-lowering properties. However, the precise mechanisms and active constituents contributing to efficacy of LPT against NAFLD remain unclear.

10.1016/j.phymed.2024.155834 article EN cc-by-nc-nd Phytomedicine 2024-06-20

Neck pain is a common condition that leads to neck motor dysfunction and subsequent disability, with significant global health care burden. As newly emerging tool, virtual reality (VR) technology has been employed address reduce disability among patients pain. However, there still lack of high-quality studies evaluating the efficacy VR therapy combined conventional rehabilitation for chronic pain, particularly in terms kinematic function.

10.2196/42829 article EN cc-by JMIR Serious Games 2024-04-24

Background Neuropathic pain (NP) can be induced by a variety of clinical conditions, such as spinal cord injury, lumbar disc herniation (LDH), stenosis, diabetes, herpes zoster, and tumors, inflammatory stimuli. The pathogenesis NP is extremely complex. Specifically, in LDH, the herniated nucleus pulposus exerts mechanical pressure on nerve roots, triggering local inflammation consequent NP. Anoikis, special form programmed cell death, closely related to progression In this study, we sought...

10.1371/journal.pone.0314773 article EN cc-by PLoS ONE 2025-02-27

ABSTRACT Purpose There are many causes of thoracic ossification the ligamentum flavum (TOLF), which mechanical stress factors have gained increasing attention. This study aimed to explore potential pathogenesis TOLF by comparing spinal sagittal alignment parameters between patients with and an asymptomatic population. Methods We retrospectively included who underwent surgical treatment for myelopathy caused OLF at Peking University Third Hospital from 2012 2022. Sagittal measured picture...

10.1111/os.70061 article EN cc-by-nc-nd Orthopaedic Surgery 2025-05-26

Individuals with mild cognitive impairment (MCI) are at increased risk for Dementia of Alzheimers type (DAT), vascular dementia (VaD), Lewy Body (LBD) and Fronto-temporal dementias (FTD). Risk factors conversion rates MCI to have not been thoroughly investigated in developing countries. Chinese English versions Mini-Mental State Examination were administered serially among well-matched subjects from two clinics located Xian, China Houston, USA. Subtle impairments weighed according criteria...

10.2174/1567205043480564 article EN Current Alzheimer Research 2004-02-01

Ethnopharmacological relevance: Hyperlipidemia as a major health issue has attracted much public attention. As geographical indication product of China, Liupao tea (LPT) is typical representative traditional Chinese dark that shown good potential in regulating glucose and lipid metabolism. LPT important medicinal value hyperlipidemia prevention. However, the active ingredients metabolic mechanisms by which alleviates remain unclear.Aim study: This study aimed to systematically investigate...

10.2139/ssrn.4728489 preprint EN 2024-01-01

Objective This study aimed to examine the levels of solute carrier family seven number 11 (SLC7A11) and glutathione peroxidase 4 (GPX4) in serum patients with acute ischaemic stroke (AIS) their relationship disease severity. Methods A total 148 AIS together healthy controls (HCs) were enrolled. The expression SLC7A11 GPX4 detected immediately as early possible. Radiographic severity was by Alberta Stroke Program Early CT Score (ASPECTS). Disease evaluated using modified Rankin Scale (mRS)....

10.1177/00045632241305927 article EN Annals of Clinical Biochemistry International Journal of Laboratory Medicine 2024-12-04

Objective To investigate the expression level and its clinical significance of multi drug resistance (MDR) associated protein in lung cancer specimens. Methods The levels Pgp, MRP, GST π TopoⅡ MDR were detected 60 samples 30 paracancerous tissues by S P immunohistochemistry method. Results positive rate Topo Ⅱ was 40.0% (24/60), 61.7% (37/60), 45.0% (27/60) 81.7% (49/60) respectively, which significantly higher than those (P0.01). No significant correlation observed among related TNM...

10.3779/j.issn.1009-3419.2002.01.10 article EN 2002-02-20

<sec> <title>BACKGROUND</title> Neck pain is a prevalent condition that causes an enormous health care burden due to the lack of efficient therapies. As promising technology, virtual reality (VR) has shown advantages in orthopedic rehabilitation. However, there no meta-analysis evaluating effectiveness VR neck management. </sec> <title>OBJECTIVE</title> This study aims review original randomized controlled trials (RCTs) for and provide evidence clinical application new alternative approach...

10.2196/preprints.38256 preprint EN 2022-03-25

<sec> <title>BACKGROUND</title> Neck pain is a common condition that leads to neck motor dysfunction and subsequent disability, with significant global health care burden. As newly emerging tool, virtual reality (VR) technology has been employed address reduce disability among patients pain. However, there still lack of high-quality studies evaluating the efficacy VR therapy combined conventional rehabilitation for chronic pain, particularly in terms kinematic function. </sec>...

10.2196/preprints.42829 preprint EN 2022-09-20
Coming Soon ...