A5056420188- Cancer-related molecular mechanisms research
- Cancer-related gene regulation
- RNA modifications and cancer
- Mitochondrial Function and Pathology
- Epigenetics and DNA Methylation
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
- Adipose Tissue and Metabolism
- Redox biology and oxidative stress
- Acute Ischemic Stroke Management
Nicolaus Copernicus University
2024-2025
Islamic Azad University, Tehran
2023-2024
Islamic Azad University Kazeron
2018
Cellular stressors have been demonstrated to exert a substantial influence on the functionality of organelles, thereby impacting cellular homeostasis and contributing development disease pathogenesis. This review aims examine impact diverse stressors, including environmental, chemical, biological, physical factors, critical organelles such as cell membrane, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, membrane-less organelles. The intricate molecular mechanisms underlying...
Abstract Background Long non-coding RNAs, known as LncRNAs, have demonstrated a robust association with the pathogenesis of stroke. NRON and SNHG are among most extensively studied lncRNAs in context atherosclerosis inflammatory conditions. Given absence current pathophysiological hypothesis regarding potential relevance family ischemic stroke (IS), this study aimed to investigate altered expression SNHG11 following atherosclerotic (AIS) their risk AIS. Methods Blood samples were collected...
Abstract Background: Aberrant promoter methylation of CpG islands is an important mechanism for regulation gene expression. Recent data suggest that epigenetic abnormalities may occur very early in lung carcinogenesis. Systemic changes be a diagnostic marker tumor development or prognosis. In this study, the expression and KMT2D IGF2 genes were investigated cancer tissue compared to adjacent normal tissue. Methods: The status 30 patients with NSCLC after genomic DNA extraction using...
Long non-coding ribonucleic acids (lncRNAs) have been implicated as possible circulating stroke indicators. This study focused on the expression status of antisense acid in INK4 locus (ANRIL) and myocardial infarction associated transcript (MIAT) patients with cerebral venous thrombosis (CVT).
Background: Aberrant promoter methylation of CpG islands is an important mechanism for regulation gene expression. Recent data suggest that epigenetic abnormalities may occur very early in lung carcinogenesis. Systemic changes be a diagnostic marker tumor development or prognosis. In this study, the expression and KMT2D IGF2 genes were investigated cancer tissue compared to adjacent normal tissue.Methods: The status 30 patients with NSCLC after genomic DNA extraction using bisulfite...
Abstract Background: Long non-coding RNAs (LncRNAs) have been implicated as possible circulating stroke indicators. This study focused on the expression status of ANRIL and MIAT in cerebral venous thrombosis (CVT) patients. Methods: In this study, fifty CVT patients one hundred age/gender-matched individuals controls were included. The levels first 24 hours after admission evaluated using quantitative real-time polymerase chain reaction (RT-PCR) method. We compared between independent...
Background: Breast cancer is a clinically heterogeneous disease. Molecular classification of breast has been proposed based on gene expression profiles human tumors. Luminal, basal-like, normal-like, and erbB2+ subgroups were identified shown to have different prognoses. the most common among women worldwide, with 1.3 million diagnosed each year about 500,000 deaths per from Recently molecular studies conducted early diagnosis cancer. In this study, levels Mir-210 Mir-141 reported in...