A5001368213- Cancer-related molecular mechanisms research
- Environmental Toxicology and Ecotoxicology
- Circular RNAs in diseases
- Biomarkers in Disease Mechanisms
- Acute Ischemic Stroke Management
- Heavy metals in environment
- Mycobacterium research and diagnosis
- RNA Research and Splicing
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA modifications and cancer
- Cytokine Signaling Pathways and Interactions
- Neurological Disease Mechanisms and Treatments
- Epigenetics and DNA Methylation
- Reproductive Biology and Fertility
- Vitamin D Research Studies
- S100 Proteins and Annexins
- Testicular diseases and treatments
- Sarcoma Diagnosis and Treatment
- Animal Nutrition and Physiology
- Vitamin C and Antioxidants Research
- Lipid metabolism and disorders
Shiraz University of Medical Sciences
2021-2024
Institute of Zoology
2019-2024
Chinese Academy of Sciences
2019-2024
University of Chinese Academy of Sciences
2024
Abstract Background RP5-833A20.1, DYNLRB2-2, and APOA1 antisense are pivotal in atherosclerotic plaque pathogenesis. This study examined whether changes these circulating lncRNAs could serve as biomarkers for high-risk ischemic stroke (IS) patients with intracranial disease (ICAD). Methods Sixty-three IS patients, presenting within the first 24 h after onset, 60 controls were included study. The levels of assessed using real-time polymerase chain reaction (RT-PCR). Results Significant...
Abstract Background Long non-coding RNAs, known as LncRNAs, have demonstrated a robust association with the pathogenesis of stroke. NRON and SNHG are among most extensively studied lncRNAs in context atherosclerosis inflammatory conditions. Given absence current pathophysiological hypothesis regarding potential relevance family ischemic stroke (IS), this study aimed to investigate altered expression SNHG11 following atherosclerotic (AIS) their risk AIS. Methods Blood samples were collected...
Background: Inflammation is the major contributor to pathophysiology of ischemic stroke (IS). Long non-coding ribonucleic acids (lncRNAs) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and tumor necrosis factor heterogeneous nuclear ribonucleoprotein L-related immunoregulatory (THRIL) have been demonstrated be up-regulated in inflammation atherosclerosis. Therefore, we aimed study expression profile these lncRNAs after IS. Methods: This observational case-control was...
Summary A study was conducted to determine whether dietary chromium (1200Â μg Cr/kg diet) and vitamin C (300Â mg/kg) attenuate the adverse effects of heat stress on external internal egg quality traits in Japanese quails. total 160 female 64 male quails were randomly assigned 4 treatment groups (4 replicates with 14 birds each; 10 females males) a completely randomized design 2 × factorial arrangement. Dietary treatments were: 1) basal diet (control; NRC recommendation), 2) supplemented...
The initial inflammatory reaction starts following occlusion in ischemic stroke (IS). Interleukin-1β (IL-1β) is a pro-inflammatory cytokine with crucial role the pathogenesis of neurodegenerative disorders.To investigate levels IL-1β and vitamin D (VitD) patients IS compared controls their correlation.The serum level 25-OH VitD was assessed 102 (0-24 h after stroke) an enzyme-linked immunosorbent assay (ELISA) kit.We found significant increase (80.14±6.8 vs. 60.32±4.1 pg/ml, p<0.05) decrease...
The cover image is based on the Letter to Editor mRNA isoform switches during mouse zygotic genome activation by Fan Li et al., https://doi.org/10.1111/cpr.13655 .
Background:Previous studies have demonstrated the strong association of inflammatory cytokines and vitamin D (VitD) deficiency ischemic stroke (IS) pathogenesis. Due to negative correlation between long non-coding RNA (lncRNA) Malat1 pro-inflammatory factors we decided investigate associations expression with serum interleukin-1β (IL-1β), VitD levels in IS patients. Materials Methods:In this cross-sectional study, 63 patients were included. We used enzyme-linked immunosorbent assays...
Previous studies have demonstrated the strong association of inflammatory cytokines and vitamin D (VitD) deficiency ischemic stroke (IS) pathogenesis. Due to negative correlation between long non-coding RNA (lncRNA) Malat1 pro-inflammatory factors we decided investigate associations expression with serum interleukin-1β (IL-1β), VitD levels in IS patients.
Abstract Background Long non-coding RNA (lncRNA) has the main role in gene regulation and it might serve as a potential biomarker clinical practice. Malat1 THRIL LncRNAs have been demonstrated to play key roles inflammation atherosclerosis. It was hypothesized that expression increase patients with atherosclerotic ischemic stroke (IS) significant diagnostic value for discriminating IS from controls. Methods We evaluated on days 1,3, 5 after 59 cases small-vessel disease (SVD) large artery...