A5025835758- Cardiac electrophysiology and arrhythmias
- Liver Disease Diagnosis and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Renin-Angiotensin System Studies
- Cardiovascular Function and Risk Factors
- Corneal surgery and disorders
- Cardiac Ischemia and Reperfusion
- Apelin-related biomedical research
- Hormonal Regulation and Hypertension
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Gastric Cancer Management and Outcomes
- Receptor Mechanisms and Signaling
- Peroxisome Proliferator-Activated Receptors
- Adipose Tissue and Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Adipokines, Inflammation, and Metabolic Diseases
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Laser Design and Applications
- Blood Coagulation and Thrombosis Mechanisms
- Biliary and Gastrointestinal Fistulas
- Metastasis and carcinoma case studies
Future University Hakodate
2024
Guilford Press (United States)
2024
Aichi Cancer Center
2011-2015
Hiroshima Institute of Technology
2015
Royal North Shore Hospital
2013
Azabu University
2010
Showa University
1997-2008
Osaka University
1990-2006
Ibaraki University
2002
Tohoku University
2002
OBJECTIVE—Recent studies have demonstrated that the treatment with thiazolidinediones reduces in-stent restenosis. The aim of this study was to elucidate mechanism efficacy pioglitazone for preventing restenosis in type 2 diabetic patients. RESEARCH DESIGN AND METHODS—We conducted a prospective, randomized trial involving 54 patients referred coronary stenting who were randomly assigned either control or group. Quantitative angiography performed at entry and 6 months follow-up. Endothelial...
The appearance of cough in association with angiotensin-converting enzyme (ACE) inhibitors is thought to be related bradykinin, and it has been speculated that the elicitation adverse effects genetically predetermined. Several polymorphisms human bradykinin B(2) receptor gene may involved ACE inhibitor-related cough. To investigate this possibility, we identified -58 thymine (T)/cytosine (C) polymorphism subjects We classified study population into 4 groups: without were treated (n=30/30),...
Abstract: We report two cases of hypertriglyceridemic necrotizing pancreatitis treated by plasma exchange (PE). The outcome each case was quite different according to the timing PE. A 36 year old man presented with abdominal pain, and a diagnosis severe acute made. His serum triglyceride (TG) level 6,460 mg/dl. He did not undergo PE at first, however, his condition never improved performed 20 days after onset illness. Finally, he died multiple organ failure sepsis. In contrast, 52 referred...
A single nucleotide polymorphism of mitochondrial 5178A/C, causing a Met to Leu replacement within the NADH dehydrogenase subunit, is reported be associated with longevity. The purpose present study was assess contribution polymorphisms, particularly 5178A/C genotype, susceptibility acute myocardial infarction (AMI) in Japanese population. There were 4 groups: 150 patients AMI, essential hypertension, 100 diabetes mellitus, and subjects matched for age sex who served as control group....
Abstract. Nishio K, Mukae S, Aoki Itoh Konno N, Ozawa Satoh R, Katagiri T (School of Medicine Showa University, Hatanodai, Shinagawa‐ku, Tokyo, Japan). Congestive heart failure is associated with the rate bone loss. J Intern Med 2003; 253: 439–446. Aims. To characterize relationships between mineral homeostasis, turnover, mass, and congestive (CHF), we evaluated 75 women mild to moderate CHF. Methods results. We examined association in annual change spinal density (BMD) polymorphism vitamin...
The present study examined the genetic contribution of human β2 bradykinin receptor gene in Japanese subjects with essential hypertension, and identified a -58T/C polymorphism core promoter that might be responsible for hypertension Japanese. consisted 100 hypertensive age- sex-matched controls. allelic frequencies were 0.575 C allele 0.425 T subjects, 0.465 0.535 normotensive subjects. Hardy-Weinberg equilibrium. Significant differences between seen genotypes distribution (p=0.049)...
AIMS/BACKGROUND: To evaluate epithelial wound healing and visual outcome of excimer laser photorefractive keratectomy (PRK) performed on high myopic eyes with contact lens intolerance due to dry eye. METHODS: PRK was two groups patients non-Sjogren9s eye: group A (-6 D -9.5 D, 11 patients, 17 eyes) B (-11.5 -19.5 16 in an attempt eliminate the use lenses (CL). The intended correction full 10 B. RESULTS: Uncorrected acuity better than 20/40 12 (80.0%) 15 at 6 months (90.9%) 1 year. Fourteen...
The renin-angiotensin system is believed to play important roles in the development of acute myocardial infarction, and gene polymorphisms may also be involved. To investigate genetic background patients with we performed a case control study Japanese population. included 150 infarction healthy, age- sex-matched controls. We examined angiotensin II type 1 receptor (1 166 A / C), 2 (3123 C A), bradykinin B2 (-58 T C) these subjects. allelic frequencies I were significantly higher subjects...
Text input in MR(Mixed Reality) provides options for users to model details instead of just placing objects, however, 3D modeling with text costs computation and takes time. To overcome this hurdle, we let the text-image judge layout furniture parts. Since vanilla can not stability, tested two approaches: 1. combine geometric loss, 2. fine-tuning model. We report comparison these approaches discuss further development MR integration our system.
This study assessed the contribution of polymorphisms angiotensin II (AngII) receptors and bradykinin B2 (BK-B2) receptor to hypertension acute myocardial infarction (AMI) in a Japanese population: 150 subjects with essential hypertension, AMI with/without healthy, age- sex-matched controls. Polymorphisms AngII type 1 (1166 A/C) 2 (3123 C/A), BK-B2 (-58T/C, exon 1) were analyzed significant differences genotypes allelic frequencies C/A -58T/C found between control subjects. Further,...
Both the (17R)- and (17S)-isomers of volicitin, which is contained in oral secretion beet armyworm induces corn seedlings to emit a blend volatile compounds attract natural enemy herbivore, were synthesized via semi-hydrogenation an intermediary diyne (Z)-selective olefination as key steps. They both obtained crystalline compounds.
The protective effect and mechanism of action the angiotensin-converting enzyme inhibitor (ACE-I) captopril was investigated in organelles from ischemic myocardial cells a canine coronary ligation model. Sarcoplasmic reticulum (SR) mitochondrial fractions were extracted nonischemic captopril- saline-treated (control) hearts. Heart rate, cardiac output, right ventricular systolic blood pressure similar captopril-treated control groups. Left (LVPs) decreased gradually to 89% baseline value...
The aim of this study was to evaluate the effect pioglitazone on nitric oxide in patients with type 2 diabetes and coronary artery disease. Twenty‐seven disease mellitus who had received stenting were eligible for study. They assigned no insulin resistance (NIR) group, (IR) group (30 mg once a day). Endothelial synthase (eNOS), inducible (iNOS), tumor necrosis factor α (TNF‐α), interleukin‐6, leptin, adiponectin measured. In eNOS, iNOS, leptin significantly lower higher than those IR group....
Athabasca bitumen was sudjected to thermal cracking at temperatures of 430-520°C in the presence hydrogen 50atm. A significant decrease viscosity and that average molecular weight were attained without excessive coke formation. The reaction mechanism discussed based on detailed structural analyses oil cracked by visbreaking use various methods including GPC, NMR, elemental analysis.