Meghan Leonard
- Neural dynamics and brain function
- Animal Genetics and Reproduction
- RNA and protein synthesis mechanisms
- Neurobiology and Insect Physiology Research
- RNA Research and Splicing
- Insect and Arachnid Ecology and Behavior
- interferon and immune responses
- RNA regulation and disease
- Animal Behavior and Reproduction
- Genomics and Chromatin Dynamics
- CCD and CMOS Imaging Sensors
- Advanced Memory and Neural Computing
Janelia Research Campus
2024-2025
Howard Hughes Medical Institute
1990-2025
Northwestern University
1990-1991
Children's Hospital
1990
Research Institute of Molecular Pathology
1990
Harvard University
1990
NF-E1, a DNA-binding protein that recognizes the general consensus motif WGATAR, is first tissue-specific factor to be identified in erythroid cells. Using probe from murine GF-1 (NF-E1) cDNA clone, we isolated three homologous chicken cDNAs: One of these corresponds an mRNA (NF-E1a) abundantly and exclusively expressed cells; second (NF-E1b) also all developmental stages cells but additionally found limited subset other tissues; representative third gene (NF-E1c) only definitive (adult)...
Vision provides animals with detailed information about their surroundings, conveying diverse features such as color, form, and movement across the visual scene. Computing these parallel spatial requires a large network of neurons, that in distant flies humans, regions comprise half brain's volume. These brain often reveal remarkable structure-function relationships, neurons organized along maps shapes directly relate to roles processing. To unravel stunning diversity complex system, careful...
Abstract Vision provides animals with detailed information about their surroundings and conveys diverse features such as colour, form movement across the visual scene. Computing these parallel spatial requires a large network of neurons. Consequently, from flies to humans, regions in brain constitute half its volume. These often have marked structure–function relationships, neurons organized along maps shapes that directly relate roles processing. More than century anatomical studies...
A family of transcriptional activators has recently been identified in chickens; these recognize a common consensus motif (WGATAR) through conserved C4 zinc finger DNA-binding domain. One the members this multigene family, cGATA-3, is most abundantly expressed T-lymphocyte cell lineage. Analysis human and murine GATA-3 factors shows striking degree amino acid sequence identity similar patterns tissue specificity expression three organisms. The are variety T-cell lines can activate...