A5092376127- Wound Healing and Treatments
- Tryptophan and brain disorders
- Dermatology and Skin Diseases
- Diabetic Foot Ulcer Assessment and Management
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Bacterial Genetics and Biotechnology
- Enzyme Structure and Function
- Immune Cell Function and Interaction
- Lysosomal Storage Disorders Research
- T-cell and B-cell Immunology
- Periodontal Regeneration and Treatments
- Glycogen Storage Diseases and Myoclonus
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Pressure Ulcer Prevention and Management
- Protist diversity and phylogeny
- Antimicrobial Peptides and Activities
- CRISPR and Genetic Engineering
- Microbial Community Ecology and Physiology
- Reproductive System and Pregnancy
- Parkinson's Disease Mechanisms and Treatments
University of Pennsylvania
2023-2025
Duke University
2018-2024
Chronic wounds are a common and costly complication of diabetes, where multifactorial defects contribute to dysregulated skin repair, inflammation, tissue damage, infection. We previously showed that aspects the diabetic foot ulcer microbiota were correlated with poor healing outcomes, but many microbial species recovered remain uninvestigated respect wound healing. Here, we focused on
Microbial cells must continually adapt their physiology in the face of changing environmental conditions. Archaea living extreme conditions, such as saturated salinity, represent important examples resilience. The model salt-loving organism Haloferax volcanii exhibits remarkable plasticity its morphology, biofilm formation, and motility response to variations nutrients cell density. However, mechanisms regulating these lifestyle transitions remain unclear. In prior research, we showed that...
The host-microbiota relationship has evolved to shape mammalian physiology, including immunity, metabolism, and development. Germ-free models are widely used study microbial effects on host processes such as immunity. Here, we find that both germ-free T cell-deficient mice exhibit a robust sebum secretion defect persisting across multiple generations despite colonization cell repletion. These phenotypes inherited by progeny conceived during in vitro fertilization using sperm eggs,...
Chronic wounds are a common and costly complication of diabetes, where multifactorial defects contribute to dysregulated skin repair, inflammation, tissue damage, infection. We previously showed that aspects the diabetic foot ulcer microbiota were correlated with poor healing outcomes, but many microbial species recovered remain uninvestigated respect wound healing. Here we focused on
ABSTRACT Colonization of human skin and nares by methicillin-resistant Staphylococcus aureus (MRSA) leads to the community spread MRSA. This is exacerbated transfer MRSA between humans livestock, particularly swine. Here, we capitalized on shared features porcine skin, including colonization, study novel bacterial mediators colonization resistance. We focused poorly studied species Desemzia incerta , which found exert antimicrobial activity through a secreted product exhibited resistance...
Microbial cells must continually adapt their physiology in the face of changing environmental conditions. Archaea living extreme conditions, such as saturated salinity, represent important examples resilience. The model salt-loving organism Haloferax volcanii exhibits remarkable plasticity its morphology, biofilm formation, and motility response to variations nutrients cell density. However, mechanisms regulating these lifestyle transitions remain unclear. In prior research, we showed that...