- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Literacy and Information Accessibility
- Genetics and Neurodevelopmental Disorders
- Neurological Disease Mechanisms and Treatments
- Heavy Metals in Plants
- Diet and metabolism studies
- Heavy metals in environment
- Garlic and Onion Studies
- Nutritional Studies and Diet
- Cholinesterase and Neurodegenerative Diseases
- Noise Effects and Management
- Air Quality and Health Impacts
- Child Nutrition and Water Access
- Osteoarthritis Treatment and Mechanisms
- Heavy Metal Exposure and Toxicity
- Pharmacological Effects of Natural Compounds
Bengbu Medical College
2024-2025
Northwest A&F University
2024
Shenzhen Bay Laboratory
2022-2023
One of the most prevalent chronic diseases, osteoarthritis (OA), may work in conjunction with
Abstract Background To better assist with the design of future clinical trials for Alzheimer’s disease (AD) and aid in our understanding disease’s symptomatology, it is essential to clarify what roles β-amyloid (Aβ) plaques tau tangles play longitudinal accumulation inside outside medial temporal lobe (MTL) as well how age, sex, apolipoprotein E (APOE) ε4 (APOE-ε4), Klotho-VS heterozygosity (KL-VS het ) modulate these relationships. Methods We divided 325 Aβ PET-positive (A+) participants...
Depression and anxiety carry an important public health burden. Indoor air pollution is associated with depression anxiety. Ventilation can reduce the concentration of indoor improve quality. This study explored relationship between ventilation frequency in older adults using data from 2018 Chinese Longitudinal Healthy Longevity Survey. Compared people low frequency, those high had 51% lower odds ( <math xmlns="http://www.w3.org/1998/Math/MathML"...
Diabetes mellitus (DM) is a major public health problem worldwide. Numerous traditional plants are used for preventing DM. However, limited evidence supports the association between garlic consumption and Data in this study was from 2008-2018 Chinese Longitudinal Healthy Longevity Survey. on obtained by questionnaire, DM self-reported diagnosis. A multivariate adjusted Cox regression model to estimate haz-ard ratios (HR) 95% confidence intervals (CI) determine incidence of total 1927...
To explore the associations between nutrition literacy (NL) and possible sarcopenia in older Chinese adults. A cross-sectional study was conducted. NL assessed using a twelve-item short-form scale. Possible identified SARC-CALF. Logistic regression used to calculate OR 95 % CI for incidence of sarcopenia. total 1338 individuals, aged 71·41 (sd 6·84) years, were enrolled this study. After confounders adjusted for, adults upper quartile found be 52 less likely have than those lower (OR = 0·48,...
Background: Body mass index (BMI) changes may be related to Alzheimer’s disease (AD) alterations, but it is unclear how the apolipoprotein E ɛ4 (APOE ɛ4) allele affects their association. Objective: To explore association of BMI with AD pathologies in APOE carriers and non-carriers. Methods: In 862 non-demented ADNI participants with≥2 measurements, we investigated relationships between slopes longitudinal amyloid-β (Aβ) accumulation, neurodegeneration cognition, follow-up tau deposition...
Abstract Objectives To explore the association between drinking water sources and cognitive functioning among older adults residing in rural China. Methods Data were extracted from 2008–2018 Chinese Longitudinal Healthy Longevity Survey. Drinking categorized according to whether purification measures employed. The version of Mini‐Mental State Examination was used for assessment, score <24 considered as having dysfunction. Cox regression analyses conducted derive hazard ratios (HRs) 95%...
Abstract Background High and low body mass index (BMI) may increase the risk of Alzheimer’s disease (AD) in mid‐life (age<65) late‐life (age≥65) respectively. However, it is still not fully understood about associations BMI changes with AD progression as well how APOE‐ε4 allele modulates their relationships late‐life. In this study, we aimed to determine relate longitudinal β‐amyloid (Aβ) accumulation, tau aggregation, neurodegeneration cognitive decline Method We examined 325 cognitively...
Abstract Background Clarifying the relative roles of β-amyloid (Aβ) plaques and tau tangles in longitudinal replication propagation inside outside medial temporal lobe (MTL) as well how age, sex, APOE-4, Klotho-VS heterozygosity (KL-VS het ) modulate their relationships Alzheimer’s disease (AD) may help with designing therapeutic clinical trials for AD aid our understanding disease’s symptoms. Methods We divided 325 Aβ PET positive (A+) participants this study into two groups, A+/T- (143)...