A5003751733- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Inflammatory Biomarkers in Disease Prognosis
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Adenosine and Purinergic Signaling
- Intensive Care Unit Cognitive Disorders
- Bone health and osteoporosis research
- Peroxisome Proliferator-Activated Receptors
- Immune cells in cancer
- Antiplatelet Therapy and Cardiovascular Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Acute Ischemic Stroke Management
- Health Literacy and Information Accessibility
- Lipid metabolism and disorders
- Lipoproteins and Cardiovascular Health
- Venous Thromboembolism Diagnosis and Management
- Acute Kidney Injury Research
- Cerebrovascular and Carotid Artery Diseases
- Health disparities and outcomes
- Cardiac electrophysiology and arrhythmias
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Health and Mental Health
Affiliated Hospital of Hebei University
2025
Nanjing University of Chinese Medicine
2025
Bengbu Medical College
2023-2024
Peking University
2024
Wannan Medical College
2021-2023
First Affiliated Hospital of Wannan Medical College
2021-2023
Soochow University
2016-2023
Deyang Stomatological Hospital
2020-2023
Lanzhou University
2023
Army Medical University
2023
Abstract Background The systemic immune-inflammation index (SII), based on peripheral platelet, neutrophil and lymphocyte counts, has been proven to be a promising prognostic indicator in various diseases. Hip fracture is common injury among the older adults, become global public health problem with high mortality disability rates. However, relationship between SII prognosis of hip not yet well-known. aim this study was explore predictive value adults undergoing surgery. Methods This...
New-onset atrial fibrillation (NOAF) is associated with worse prognostic outcomes in cases diagnosed ST-segment elevation myocardial infarction (STEMI) patients after percutaneous coronary intervention (PCI). The triglyceride-glucose (TyG) index, as a credible and convenient marker of insulin resistance, has been shown to be predictive for STEMI following revascularization. association between TyG index NOAF among PCI, however, not established date.To assess the utility predictor incidence...
To explore the association of diabetic retinopathy (DR) with TyG index and TyG-related parameters among United States population.This cross-sectional study is conducted in adults diabetes mellitus based on National Health Nutrition Examination Survey (NHANES) from 2005 to 2018. Multivariate logistic regression, restricted cubic spline, trend test, receiver operating characteristic curve subgroup analysis are adopted uncover DR parameter levels diabetics.An aggregate 888 eligible participants...
Abstract Background The excessive consumption of take-out food has increased the risk nutrition-related chronic diseases. Nutrition literacy (NL) is an important influencing factor choice. This study aimed to explore relationship between nutrition and consumption. Methods A cross-sectional was conducted on 2130 college students in Bengbu, China. self-reported questionnaire that included demographic information, lifestyle behavior, consumption, scale used. Ordinal logistic regression models...
Depression and anxiety carry an important public health burden. Indoor air pollution is associated with depression anxiety. Ventilation can reduce the concentration of indoor improve quality. This study explored relationship between ventilation frequency in older adults using data from 2018 Chinese Longitudinal Healthy Longevity Survey. Compared people low frequency, those high had 51% lower odds ( <math xmlns="http://www.w3.org/1998/Math/MathML"...
Background/Aims: Trastuzumab is an important treatment used for patients with Her-2-positive breast cancer, but increasing incidence of trastuzumab resistance has been observed clinically during the past decade. Aberrant microRNA (miR) expression levels are correlated prognosis and response to in cancer. MiR-129-5p downregulated trastuzumab-resistant human cancer cells (JIMT-1), its potential function underlying mechanism remain unclear. Methods: Quantitative RT-PCR (qRT-PCR) was determine...
Objective: To compare the hemodynamic stability of etomidate and remimazolam during painless gastroscopy evaluate safety in elderly patients undergoing gastroscopy. Methods: A total 100 aged 65–80 years, with American Society Anesthesiologists (ASA) physical status I–II, who underwent gastrointestinal endoscopy were included this study. The randomly assigned to receive either 0.2 mg/kg (Group R) or 0.3 (E group) combination alfentanil for anesthesia induction. Results: mean arterial pressure...
Abstract Background New-onset atrial fibrillation (NOAF) complicating with ST-elevated myocardial infarction (STEMI) patients following percutaneous coronary intervention (PCI) is associated worse prognosis. The systemic inflammatory response index (SIRI), serves as a novel indicator, found to be predictive of adverse outcomes. aim this study explore the association between NOAF and SIRI. Methods A retrospective data included 616 STEMI participants treated PCI in our cardiology department...
Elderly patients with lower-extremity fractures are at high risk of postoperative pneumonia (POP) after surgery due to longtime bed rest. This study aimed explore whether preoperative frailty is an independent factor for POP in elderly undergoing surgical treatment fractures. The adopted a cross sectional design 568 (≥60 years) admitted tertiary hospital China from January 1, 2021 June 30, 2022, intervention significant fracture. Preoperative was assessed using the CFS (Clinical Frailty...
Epithelial ovarian cancer (EOC) is a lethal form of gynecological malignancy. Some EOC patients experience relapse after standard primary debulking surgery (PDS) and adjuvant chemotherapy (ACT). Identifying molecular residual disease (MRD) by circulating tumor DNA (ctDNA) detection can timely signal the potential for relapse. However, research on usage ctDNA MRD in limited. Fifty-one who received PDS ACT were included. Targeted sequencing based panel 1021 cancer-related genes, along with...
Trichloroethylene (TCE) induced occupational medicamentosa-like dermatitis (OMLDT) in patients is accompanied, typically, by renal damage. But the role of C5b-9 and IL-1β TCE-sensitized mouse tubular damage unclear. This study aimed to investigate whether epithelial cell was NLRP3 inflammasome activated sublytic C5b-9. In total, 52 specific pathogen-free BALB/c female mice, 6- 8-week-old, were used for establishing model. Renal cells isolated determining level Kidney histological...
Background Myeloid-derived suppressor cell (MDSC) mobilisation is an important immune event in acute myocardial infarction (AMI). The A2B adenosine receptor (A2BAR) plays key role regulating MDSC function, but its specific involvement AMI remains unclear.Methods In patients, the circulating ratio and A2BAR mRNA expression were measured. A mouse model was established by left anterior descending coronary artery (LADCA) ligation. MDSCs analysed FACS immunofluorescence staining (of heart...
Nifedipine is widely used to treat high blood pressure and angina. Were nifedipine able promote the proliferation migration of breast cancer, it would pose a significant threat for patients. Thus, important determine effects on cancer mechanism involved. The present study identified that significantly promoted cells in vitro. different was investigated MCF‑7 were via protein kinase B‑endothelial constitutive nitric oxide synthase‑nitric axis, MDA‑MB‑231 activation extracellular...
The purpose of this study was to explore whether renal endothelial cell injury is associated with oxidative stress in trichloroethylene (TCE)-induced immune kidney damage by detecting adhesion molecules and indexes. In study, a mouse model skin sensitization the antioxidant Tempol used mechanism. Blood urea nitrogen (BUN), creatinine (Cre), histological examination were for function evaluation. Kidney homogenates nitric oxide (NO), synthase (NOS), superoxide dismutase (SOD) malondialdehyde...
Abstract Background To investigate whether hypocalcemia influenced total blood loss and transfusion rate in elderly patients with hip fracture. Methods From our fracture database, were consecutively included between January 2014 December 2020. Serum calcium level was corrected for albumin concentration, hypocalcaemia defined as < 2.11 mmol/L. Hemoglobin hematocrit obtained on admission day postoperative day, transfusions collected. According to the combination formulas of Nadler Gross,...
Background Severe burn injury can be a life-threatening experience and also lead to financial issues for suffers. The purpose of the current study was analyze direct hospitalization costs severe inpatients in Southwest China. Methods Data related all admitted with burns [total body surface area (TBSA) ≥30%] pooled from 2015 2021 were reviewed retrospectively at Institute Burn Research Army Medical University. Demographic parameters, medical economics, clinical data obtained records. Results...
The present investigation was developed for the exploration of association between IL-6 levels and acute coronary syndrome (ACS) findings upon angiographic evaluation.A retrospective review 346 patients suffering from chest discomfort that underwent angiography performed. SYNergy Percutaneous Coronary Intervention with TAXus cardiac surgery (SYNTAX) score (SS) SS II were used to gauge ACS severity, being stratified into two groups based on an value 22 median value. Associations or values...
Purpose Triglyceride-glucose (TyG) index is a reliable and inexpensive alternative indicator of insulin resistance. Previous studies have shown that elevated TyG increases the risk diabetes, coronary heart disease, other diseases, but relationship between cardiac hemodynamics in patients with type 2 diabetes mellitus (T2DM) not clear. This study was conducted T2DM to assess its predictive ability for T2DM. Methods A total 647 individuals (348 males 299 females) were enrolled this study,...
The present study explores the relationship between glycemic excursion and bone turnover markers.A total of 250 patients with type 2 diabetes mellitus (T2DM) (142 female 108 male patients) were enrolled in this study. All participants underwent 72 hours continuous monitoring to evaluate mean amplitude excursions (MAGE) each person. Bone markers other biochemical data measured for patient. Linear regression was performed explore excursion. A value P < 0.05 considered statistically...
Trichloroethylene (TCE) is known to induce skin disorders and multi-system dysfunction, but the mechanism of this multi-organ injury not entirely clear. It was shown in a previous study that levels pivotal end-products kallikrein-kinin system (KKS), i.e. bradykinin (BK) BK receptors B1R/B2R, kidneys were increased by TCE exposure. Unfortunately, how its acted etiology induced renal Thus, explored any correlation between immune TCE-sensitized mice blocking B1R/B2R. BALB/c sensitized (via...