A5017953687- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Risk Factors
- Cardiovascular Effects of Exercise
- Aortic Disease and Treatment Approaches
- Superconducting Materials and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Education and Admissions
- Apelin-related biomedical research
- Global Health Workforce Issues
- Diversity and Career in Medicine
- Cardiac tumors and thrombi
- Cardiac Structural Anomalies and Repair
- Cardiac Fibrosis and Remodeling
- Sarcoma Diagnosis and Treatment
- Aortic aneurysm repair treatments
Stanford University
2022-2024
BACKGROUND: Pathogenic concepts of right ventricular (RV) failure in pulmonary arterial hypertension focus on a critical loss microvasculature. However, the methods underpinning prior studies did not take into account 3-dimensional (3D) aspects cardiac tissue, making accurate quantification difficult. We applied deep-tissue imaging to pressure-overloaded RV uncover 3D properties microvascular network and determine whether deficient adaptation contributes failure. METHODS: Heart sections...
Background and aims There are a limited number of pharmacologic therapies for coronary artery disease, few rodent models occlusive atherosclerosis consequent myocardial infarction with which one can rapidly test new therapeutic approaches. Here, we characterize novel, fertile, easy-to-use HDL receptor (SR-B1)-based model atherogenic diet-inducible, fatal atherosclerosis, the SR-B1ΔCT/LDLR KO mouse. Additionally, intramyocardial injection Stromal Cell-Derived Factor-1 alpha (SDF-1α), potent...
Despite a growing number of women entering medical school, small proportion pursue surgical specialties, including pediatric surgery. This multi-center study assesses gender-based differences in measures scholarly productivity and distribution faculty positions.
Introduction: Right ventricular (RV) failure is the leading cause of death in patients with pulmonary arterial hypertension (PAH). Capillary rarefaction has been proposed as hallmark RV failure, yet our understanding capillary architecture limited by 2D image analysis. Three-dimensional (3D) confocal deep tissue imaging offers unparalleled opportunity to characterize architectural microvascular changes relationship cardiomyocytes pressure-overloaded failure. Methods and Results: 250 μm heart...
Central MessageAutotransplantation can be used as a technique to allow for safe tumor resection when cardiac involves both the left atrium and ventricle. Autotransplantation The patient provided written informed consent publication of this report. A previously healthy 25-year-old male presenting with sharp pleuritic chest pain was found have an intracardiac mass. transthoracic echocardiogram (TTE) revealed 3- × 2-cm echolucent structure within posterolateral myocardium at level mitral...
Introduction: With more people working from home after the COVID pandemic, it is of utmost importance to further understand impact social isolation on outcomes patients with coronary atherosclerosis. Our preliminary studies have shown that novel diet-inducible, fatal mouse model atherosclerosis, SR-BIΔCT/LDLR KO , tend die average around 4-6 weeks starting a high-fat Paigan diet (HFD). This can be used effect cardiovascular disease. We hypothesize will decrease survival and worsen cardiac...